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Nitric Oxide Physiology and Pathology

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Nitric Oxide

Part of the book series: Methods in Molecular Biology ((MIMB,volume 704))

Abstract

Nitric oxide (NO) is just one member of a new class of gaseous signalling molecules with fundamental actions in biology. In higher vertebrates it has key roles in maintaining haemostasis and in smooth muscle (especially vascular smooth muscle), neurons and the gastrointestinal tract. It is intimately involved in regulating all aspects of our lives from waking, digestion, sexual function, perception of pain and pleasure, memory recall and sleeping. Finally, the way it continues to function in our bodies will influence how we degenerate with age. It will likely play a role in our deaths through cardiovascular disease, stroke, diabetes and cancer. Our ability to control NO signalling and to use NO effectively in therapy must therefore have a major bearing on the future quality and duration of human life.

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Authors and Affiliations

  1. School of Pharmacy, Queen’s University Belfast, BT9 7BL, Belfast, UK

    David G. Hirst & Tracy Robson

Authors
  1. David G. Hirst
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  2. Tracy Robson
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Correspondence to David G. Hirst .

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Editors and Affiliations

  1. School of Pharmacy, Queen's University, Belfast, Lisburn Road 97, Belfast, BT9 7BL, United Kingdom

    Helen O. McCarthy

  2. School of Pharmacy, Queen's University, Belfast, Lisburn Road 97, Belfast, BT9 7BL, United Kingdom

    Jonathan A. Coulter

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© 2011 Springer Science+Business Media, LLC

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Hirst, D.G., Robson, T. (2011). Nitric Oxide Physiology and Pathology. In: McCarthy, H., Coulter, J. (eds) Nitric Oxide. Methods in Molecular Biology, vol 704. Humana Press. https://doi.org/10.1007/978-1-61737-964-2_1

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  • DOI: https://doi.org/10.1007/978-1-61737-964-2_1

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  • Publisher Name: Humana Press

  • Print ISBN: 978-1-61737-963-5

  • Online ISBN: 978-1-61737-964-2

  • eBook Packages: Springer Protocols

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