Abstract
This chapter describes the production and characterization of antibodies raised against neoepitopes in collagenase-cleaved collagen. It also details the development, validation, and use of immunoassays using such antibodies to measure specifically collagenase-mediated cleavage.
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References
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Acknowledgments
Financial support for these studies was provided by the Shriners Hospitals for Children, Canadian Institutes of Health Research, National Institutes of Health (to Robin Poole), and the Fonds de la Recherche en Sante du Quebec (to R. Clark Billinghurst).
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Billinghurst, R.C., Ionescu, M., Poole, A.R. (2010). Immunoassays for Collagenase-Mediated Cleavage of Type I and II Collagens. In: Clark, I. (eds) Matrix Metalloproteinase Protocols. Methods in Molecular Biology, vol 622. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60327-299-5_21
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DOI: https://doi.org/10.1007/978-1-60327-299-5_21
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