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Delivery of Therapeutic Genes to Brain and Intracerebral Tumors

  • Chapter
Gene Therapy for Neurological Disorders and Brain Tumors

Part of the book series: Contemporary Neuroscience ((CNEURO))

Abstract

Delivery is a major issue in the treatment of neurological disease and tumors affecting the central nervous system (CNS). Delivery of genetic material to target cells at the molecular level has been reviewed elsewhere (please see the preceding chapters for reviews of new vectors and toxic genes for tumor therapy). Here we will address the macroscopic problem of delivery of vectors to brain tumors.

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Authors
  1. Leslie L. Muldoon
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  2. Robert A. Kroll
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  3. Michael A. Pagel
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  4. Simon Roman-Goldstein
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  5. Edward A. Neuwelt
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Editor information

Editors and Affiliations

  1. Molecular Neuro-Oncology, Neurosurgical Service, Massachussetts General Hospital, Harvard Medical School, Boston, MA, USA

    E. Antonio Chiocca MD, PhD

  2. Neurogenetics Unit, Massachussetts General Hospital, Harvard Medical Center, Boston, MA, USA

    Xandra O. Breakefield PhD

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Muldoon, L.L., Kroll, R.A., Pagel, M.A., Roman-Goldstein, S., Neuwelt, E.A. (1998). Delivery of Therapeutic Genes to Brain and Intracerebral Tumors. In: Chiocca, E.A., Breakefield, X.O. (eds) Gene Therapy for Neurological Disorders and Brain Tumors. Contemporary Neuroscience. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-478-8_14

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  • DOI: https://doi.org/10.1007/978-1-59259-478-8_14

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4757-5314-1

  • Online ISBN: 978-1-59259-478-8

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