Skip to main content
SpringerLink
Log in

Introduction

Perspectives on Cingulate Cortex in the Limbic System

  • Chapter
Neurobiology of Cingulate Cortex and Limbic Thalamus

Abstract

Because of the brain’s extensive interconnections, it is sometimes said that it is impossible to establish limits on a system of structures and, therefore, makes no sense to speak of a “limbic” system. Based, however, on the comparative morphology of the mammalian brain and what is known about its functional neuroanatomy, one can, by the application of Occam-type rules of definition, arrive at an acceptable construct of what is meant by the term limbic system. The central unifying concept of the limbic system is that, in a modular sense, limbic cortex and its primary brainstem connections constitute a functionally integrated system.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Abbie AA (1942): Cortical lamination in a poly-protodont marsupial, Perameles nasuta. J Comp Neurol 76:509–536

    Article  Google Scholar 

  • Ariëns Kappers CU (1909): The phylogenesis of the palaeo-cortex and archi-cortex compared with the evolution of the visual neo-cortex. Arch Neurol Psychiatry 4:161–173

    Google Scholar 

  • Beyer CF, Anguiano GL, Mena FJ (1961): Oxytocin release in response to stimulation of cingulate gyrus. Am J Physiol 200:625–627

    Google Scholar 

  • Brink AS (1955): Note on a very tiny specimen of Thrinaxodon liorhinus. Palaeontol Afr 3:73–76

    Google Scholar 

  • Broca P (1878): Anatomie comparée des circonvolutions cérébrales. Le grand lobe limbique et la scissure limbique dans la série des mammifères. Rev Anthropol l:Ser 2:456–498

    Google Scholar 

  • Broca P (1879): Localisations cérébrales: Recherches sur les centres olfactifs. Rev Anthropol 2:385–455

    Google Scholar 

  • Brodmann K (1906): Beiträge zur histologischen Lokalisation der Grosshirnrinde. Fünfte Mitteilung: Über den allgemeinen Bauplan des Cortex pallii bei den Mammaliern und zwei homologe Rindenfelder im bensondern. Zugleich ein Beitrag zur Furchenlehre. J Psychol Neurol 6:275–400

    Google Scholar 

  • Clark WEL, Meyer M (1950): Anatomical relationships between the cerebral cortex and the hypothalamus. Br Med Bull 6:341–345

    Google Scholar 

  • Creutzfeldt OD (1956): Die Krampfausbreitung im Temporallappen der Katze. Die Krampfent-ladungen des Ammonshorns und ihre Beziehungen zum übrigen Rhinencephalon und Iso-cortex. Schweiz Arch Neurol Psychiatr 77:163–194

    Google Scholar 

  • Dart RA (1935): The dual structure of the neopallium: Its history and significance. J Anat 69:3–19

    Google Scholar 

  • Feindel W, Penfield W (1954): Localization of discharge in temporal lobe automatism. AMA Arch Neurol Psychiatry 72:605–630

    Article  Google Scholar 

  • Flanigan S, Gabrieli ER, MacLean PD (1957): Cerebral changes revealed by radioautography with S35-labeled L-methionine. AMA Arch Neurol Psychiatry 77:588–594

    Article  Google Scholar 

  • Friedman HM, Allen N (1969): Chronic effects of complete limbic lobe destruction in man. Neurology 19:679–690

    Article  Google Scholar 

  • Gibbs EL, Gibbs FA, Fuster B (1948): Psychomotor epilepsy. Arch Neurol Psychiatry 60:313–339

    Article  Google Scholar 

  • Gibbs FA, Gibbs EL, Lennox WG (1938): Cerebral dysrhythmias of epilepsy. Arch Neurol Psychiatry 39:298–314

    Article  Google Scholar 

  • Hiller JM, Pearson J, Simon EJ (1973): Distribution of stereospecific binding of the potent narcotic analgesic etorphine in the human brain: Predominance in the limbic system. Res Commun Chem Pathol Pharmacol 6:1052–1062

    Google Scholar 

  • Insel TR, Shapiro LE (1992): Oxytocin receptor distribution reflects social organization in monogamous and polygamous voles. Proc Natl Acad Sci USA 89:5981–5985

    Article  Google Scholar 

  • Jasper HH (1964): Some physiological mechanisms involved in epileptic automatisms. Epilepsia 5:1–20

    Article  Google Scholar 

  • Jones EG, Powell TPS (1970): An anatomical study of converging sensory pathways within the cerebral cortex of the monkey. Brain 93:793–820

    Article  Google Scholar 

  • Kaada BR (1951): Somato-motor, autonomic and electrocorticographic responses to electrical stimulation of ‘rhinencephalic’ and other structures in primates, cat and dog. A study of responses from the limbic, subcallosal, orbito-insular, piriform and temporal cortex, hippo-campus-fornix and amygdala. Acta Physiol Scand 23(Suppl 83): 1–285

    Google Scholar 

  • Kuhar MJ, Pert CB, Snyder SH (1973): Regional distribution of opiate receptor binding in monkey and human brain. Nature (London) 245:447–450

    Article  Google Scholar 

  • Lassek AM (1957): The Human Brain, From Primitive to Modern. Springfield, IL: Thomas

    Google Scholar 

  • LeDoux JE (1991): Neuroscience commentary: Emotion and the brain. J NIH Res 3:49–51

    Google Scholar 

  • Levitt P (1984): A monoclonal antibody to limbic system neurons. Science 223:299–301

    Article  Google Scholar 

  • Lorente de Nó R (1933): Studies on the structure of the cerebral cortex: I. The area entorhinalis. J Psychol Neurol 45:381–438

    Google Scholar 

  • MacLean PD (1949): Psychosomatic disease and the “visceral brain.” Recent developments bearing on the Papez theory of emotion. Psy-chosom Med 11:338–353

    Google Scholar 

  • MacLean PD (1952): Some psychiatric implications of physiological studies on frontotemporal portion of limbic system (visceral brain). Elec-troencephalogr Clin Neurophysiol 4:407–418

    Article  Google Scholar 

  • MacLean PD (1957): Chemical and electrical stimulation of hippocampus in unrestrained animals. I. Methods and electroencephalogra-phic findings. AMA Arch Neurol Psychiatry 78:113–127

    Article  Google Scholar 

  • MacLean PD (1959): The limbic system with respect to two basic life principles. In: Transactions of the Second Conference on the Central Nervous System and Behavior, Brazier MAB, ed. New York: Josiah Macy Jr Foundation, pp 31–118

    Google Scholar 

  • MacLean PD (1978): Challenges of the Papez heritage. In: Limbic Mechanisms, Livingston K, Hornkiewicz O, eds. New York: Plenum, pp 1–15

    Google Scholar 

  • MacLean PD (1990): The Triune Brain in Evolution. Role in Paleocerebral Functions. New York: Plenum

    Google Scholar 

  • MacLean PD, Arellano Z, AP (1950); Basal lead studies in epileptic automatisms. Electroen-cephalogr Clin Neurophysiol 2:1–16

    Article  Google Scholar 

  • MacLean PD, Newman JD (1988): Role of midline frontolimbic cortex in production of the isolation call of squirrel monkeys. Brain Res 45:111–123

    Article  Google Scholar 

  • Melis MR, Argiolas A, Gessa GL(1986): Oxytocin-induced penile erection and yawning: Site of action in the brain. Brain Res 398:259–265

    Article  Google Scholar 

  • Murphy MR, MacLean PD, Hamilton SC (1981): Species-typical behavior of hamsters deprived from birth of the neocortex. Science 213:459–461

    Article  Google Scholar 

  • Newman JD, Murphy MR, Harbaugh CR (1982): Naloxone-reversible suppression of isolation call production after morphine injections in squirrel monkeys. Soc Neurosci Abstr 8:940

    Google Scholar 

  • Pagni CA (1963): Étude électro-clinique des postdécharges amygdalo-hippocampiques chez l’homme par moyen d’électrodes de profondeur placées avec méthode steréotaxique. Confin Neurol 23:477–499

    Article  Google Scholar 

  • Panksepp J, Herman B, Conner R, Bishop P, Scott JP (1978): The biology of social attachments: Opiates alleviate separation distress. Biol Psychiatry 13:607–618

    Google Scholar 

  • Papez JW (1937): A proposed mechanism of emotion. Arch Neurol Psychiatry 38:725–743

    Article  Google Scholar 

  • Penfield W, Jasper H (1954): Epilepsy and the Functional Anatomy of the Human Brain. Boston: Little, Brown

    Google Scholar 

  • Penfield W, Rasmussen T (1952): The Cerebral Cortex of Man. New York: Macmillan, 248 pp

    Google Scholar 

  • Pribram KH, Kruger L (1954): Functions of the “olfactory brain.” Ann NY Acad Sci 58:109–138

    Article  Google Scholar 

  • Pribram KH, MacLean PD (1953): Neuronographic analysis of medial and basal cerebral cortex. II. Monkey. J Neurophysiol 16:324–340

    Google Scholar 

  • Rose M (1926): Über das histogenetische Prinzip der Einteilung der Grosshirnrinde. J Psychol Neurol 32:97–160

    Google Scholar 

  • Rose M (1927): Gyrus limbicus anterior und Regio retrosplenialis. (Cortex holoprotopty-chos quinquestratificatus.) Vergleichende Architektonik bei Tier und Mensch. J Psychol Neurol 35:65–173

    Google Scholar 

  • Rubens AB (1975): Aphasia with infarction in the territory of the anterior cerebral artery. Cortex 11:239–250

    Article  Google Scholar 

  • Sanides F (1969): Comparative architectonics of the neocortex of mammals and their evolutionary interpretation. Ann NY Acad Sci 16:404–423

    Article  Google Scholar 

  • Schäfer EA (1900): The cerebral cortex. In: Text-Book of Physiology, Schäfer EA, ed. Edinburgh and London: Young J Pentland, Vol 2, pp 1–1365

    Google Scholar 

  • Slotnick BM (1967): Disturbances of maternal behavior in the rat following lesions of the cingulate cortex. Behaviour 24:204–236

    Article  Google Scholar 

  • Smith GE (1901): Notes upon the natural subdivision of the cerebral hemisphere. J Anat Physiol 35:431–454

    Google Scholar 

  • Smith GE (1902): On the homologies of the cerebral sulci. J Anat 36:309–319

    Google Scholar 

  • Smith GE (1910): The term “archipallium, ” a disclaimer. Anat Anz 35:429

    Google Scholar 

  • Smith GE (1919): The significance of the cerebral cortex (Croonian Lectures). Br Med J 1:796–797, 2:11–12

    Article  Google Scholar 

  • Smith WK (1945): The functional significance of the rostral cingular cortex as revealed by its responses to electrical excitation. J Neurophysiol 8:241–255

    Google Scholar 

  • Stamm JS (1955): The function of the median cerebral cortex in maternal behavior of rats. J Comp Physiol Psychol 47:21–27

    Article  Google Scholar 

  • Van Hoesen GW, Pandya DN (1975): Some connections of the entorhinal (area 28) and perirhinal (area 35) cortices of the rhesus monkey. I. Temporal lobe afferents. Brain Res 95:1–24

    Article  Google Scholar 

  • Vogt BA, Pandya DN (1987): Cingulate cortex of the rhesus monkey: II. Cortical afferents. J Comp Neurol 262:271–289

    Article  Google Scholar 

  • Vogt BA, Pandya DN, Rosene DL (1987): Cingulate cortex of the rhesus monkey: I. Cytoarchi-tecture and thalamic afferents. J Comp Neurol 262:256–270

    Article  Google Scholar 

  • Wise SP, Herkenham M (1982): Opiate receptor distribution in the cerebral cortex of the rhesus monkey. Science 218:387–389

    Article  Google Scholar 

  • Zacco A, Cooper V, Chantier PD, Fisher-Hyland S, Horton HL, Levitt P (1990): Isolation, biochemical characterization and ultrastructural analysis of the limbic system-associated membrane protein (LAMP), a protein expressed by neurons comprising functional neural circuits. J Neurosci 10:73–90

    Google Scholar 

Download references

Authors
  1. Paul D. MacLean
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Physiology and Pharmacology Bowman Gray School of Medicine, Wake Forest University, 27157-1083, Winston-Salem, NC, USA

    Brent A. Vogt

  2. Department of Psychology Beckman Institute, University of Illinois, 61801, Urbana, IL, USA

    Michael Gabriel

Rights and permissions

Reprints and permissions

Copyright information

© 1993 Springer Science+Business Media New York

About this chapter

Cite this chapter

MacLean, P.D. (1993). Introduction. In: Vogt, B.A., Gabriel, M. (eds) Neurobiology of Cingulate Cortex and Limbic Thalamus. Birkhäuser, Boston, MA. https://doi.org/10.1007/978-1-4899-6704-6_1

Download citation

  • DOI: https://doi.org/10.1007/978-1-4899-6704-6_1

  • Publisher Name: Birkhäuser, Boston, MA

  • Print ISBN: 978-1-4899-6706-0

  • Online ISBN: 978-1-4899-6704-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation