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The Role of Small t Antigen in SV40 Oncogenesis

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Molecular Basis of Human Cancer

Part of the book series: NATO ASI Series ((NSSA,volume 209))

Abstract

Simian virus 40 (SV 40) is an oncogenic papovavirus capable of inducing tumors in rodents and of transforming cells from many species in tissue culture (Topp, et al. 1981). Due to the small size of its genome, about 5000 bp, SV40 has been extensively studied as a model for understanding mechanism of viral oncogenesis in rodents.

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Author information

Authors and Affiliations

  1. Section on Viruses and Cellular Biology, NICHD, Bethesda, MD, 20982, USA

    M. Carbone, F. Pompetti, C. Cicala, P. Nguyen, K. Dixon & A. S. Levine

Authors
  1. M. Carbone
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  2. F. Pompetti
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  3. C. Cicala
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  4. P. Nguyen
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  5. K. Dixon
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  6. A. S. Levine
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Editor information

Editors and Affiliations

  1. University of Genoa, Genoa, Italy

    Claudio Nicolini

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© 1991 Springer Science+Business Media New York

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Carbone, M., Pompetti, F., Cicala, C., Nguyen, P., Dixon, K., Levine, A.S. (1991). The Role of Small t Antigen in SV40 Oncogenesis. In: Nicolini, C. (eds) Molecular Basis of Human Cancer. NATO ASI Series, vol 209. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2563-3_11

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  • DOI: https://doi.org/10.1007/978-1-4899-2563-3_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-2565-7

  • Online ISBN: 978-1-4899-2563-3

  • eBook Packages: Springer Book Archive

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