Abstract
The late stage of baculovirus infection is defined as those events that occur following the initiation of viral DNA replication and is usually subdivided into late and very late phases. These phases coincide with the production of the budded and occluded forms of the virus, respectively (see Chapters 2 and 4, this volume). Budded viruses (BVs) are produced by the packaging of newly synthesized viral DNA into nucleocapsids that leave the nucleus and bud through the cell’s plasma membrane. Occluded viruses (OVs) are produced later when the nucleocapsids become enveloped within the nucleus; the resulting virions are then embedded in a crystalline protein matrix, thereby forming nuclear bodies known as polyhedra or granules, depending on their morphological appearance, which, in turn, specifies their genus (nucleopolyhedrosis virus or granulosis virus, respectively).
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Lu, A., Miller, L.K. (1997). Regulation of Baculovirus Late and Very Late Gene Expression. In: Miller, L.K. (eds) The Baculoviruses. The Viruses. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1834-5_8
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