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Human Retroviruses: HTLV-I and HTLV-II

  • Chapter
The Retroviridae

Part of the book series: The Viruses ((VIRS))

Abstract

Human T-cell leukemia viruses, type I (HTLV-I) and type II (HTLV-II), have been extensively investigated during the past decade. In 1977 Takatsuki and his colleagues first identified adult T-cell leukemia (ATL) as a disease entity characterized by pleomorphic leukemia/lymphoma cells with deformed nuclei and the clustering of patients to southwest Japan (Takatsuki et al., 1977; Uchiyama et al., 1977). The geographical restriction of ATL patients suggested that a virus was causally related to ATL.

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Authors and Affiliations

  1. Department of Microbiology, Tohoku University School of Medicine, Sendai 980, Japan

    Kazuo Sugamura

  2. Shionogi Institute for Medical Science, Osaka 566, Japan

    Yorio Hinuma

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  1. Kazuo Sugamura
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  2. Yorio Hinuma
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  1. School of Medicine, University of California, San Francisco, California, USA

    Jay A. Levy

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Sugamura, K., Hinuma, Y. (1993). Human Retroviruses: HTLV-I and HTLV-II. In: Levy, J.A. (eds) The Retroviridae. The Viruses. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1627-3_7

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