Abstract
The highly polymorphic nature of Variable Number Tandem Repeat (VNTR) loci have made these DNA markers useful in the examination of the genetic structure of human populations (Hartmann et al., 1994; McComb et al., 1995a). A VNTR locus is characterized by a sequence of DNA bases which is repeated over a section of DNA. The number of repeats is variable, sometimes few in number, and thus exhibiting a small allele. In other cases, the repeats are numerous, and the locus has a large allele. Thus, a VNTR allele can be characterized by its length.
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References
Bowles, G.T., 1977, The People of Asia, Charles Scribner’s Sons, New York.
Crawford, M.H., Dykes, D.D., Skradski, K., and Polesky, H.F., 1979, Gene flow and genetic microdifferentiation of a transplanted Tlaxcaltecan Indian population: Saltillo, Am.J.Physical Anthr. 50: 401.
Hannigan, J. 1991, Statistics on the economic and cultural development of the northern aboriginal people of the USSR (for the period of 1980–1989 ), Bureau of Indian and Northern Affairs, Ottawa.
Harding, R.M., 1992, VNTRs in Review, Evolutionary Anthropology 1: 62.
Harpending, H., and Jenkins, T., 1973, Genetic distances among southern African populations, in: “Methods and Theories of Anthropological Genetics ”, M.H. Crawford and P.L Workman (eds), University of New Mexico Press, Albuquerque.
Harpending, H., and Ward, RH., 1982, Chemical systematics and human populations, in: “Biological Aspects of Evolutionary Biology ”, M.H. Nitecki (ed), University of Chicago Press, Chicago.
Hartmann, J., Keister, R., Houlihan, B., Thompson, L, Baldwin, R., Buse, E, Driver, B., and Kuo, M., 1994, Diversity of ethnic and racial VNTR RFLP fixed-bin frequency distributions, Am. J. Human Genet. 55: 1268.
Jeffreys, A.J., Royle, N.J., Wilson, V., and Wong, Z., 1988, Spontaneous mutation rates to new length alleles at tandem-repetitive hypervariable loci in human DNA, Nature 332: 278.
Kidd, J.R., Black, F.L, Weiss, K.M., Balazs, I., and Kidd, K.K., 1991, Studies of three Amerindian populations using nuclear DNA polymorphisms, Human Biology 63: 775.
McComb, J., Blagitko, N., Comuzzie, A.G., Schanfield, M.S., Sukernik, R.I., Leonard, W.R. and Crawford, M.H., 1995a, VNTR DNA variation in Siberian indigenous populations, Human Biology 67: 217.
McComb, J., Crawford, M.H., Osipova, L, Karaphet, T., Posukh, O., and Schanfield M.S., 1995b, DNA inter-populational variation in Siberian indigenous populations: the mountain Altai, Am. J. of Human Bio.,in press.
Nei, M., 1973, Analysis of gene diversity in subdivided populations, Proc. Nat. Acad. Sci. USA 70 (12): 3321.
Okladnikov, A.P., 1950, The initial stages of formation of the people of Siberia: the population of the Cis-Baykal region during the Neolithic and Early Bronze ages, Sovetskaya Etnografiya 2.
Popov, A.A., and Dolgikh, B.O., 1964, The Kets, in: “ The Peoples of Siberia ”, M.G. Levin and LP. Potapov (eds), University of Chicago Press, Chicago. Popov, LP., 1964, The Altays, in: “ The Peoples of Siberia ”, M.G. Levin and L.P. Potapov (eds), University of Chicago Press, Chicago.
Sokal, RR, and Rohlf, F.J., 1981, Biometry, 2nd ed, Freeman, San Francisco. Torroni, A.
Sukernik, RI., Schurr, T.G., Starikovskaya, Y.B., Cabell, M.F., Crawford, M.H., Comuzzie, A.G., and Wallace, D.C., 1993, mtDNA variation of aboriginal Siberians reveals distinct genetic affinities with Native Americans, Am. J. Human Genet. 53: 591.
Vasilevich, G.M., 1946, The oldest ethnonyms of Asia and the names of Evenki clans, Sovetskaya Etnografiya 4.
Vasilevich G.M., and Smolyak A.V., 1964, The Evenks, in: “ The Peoples of Siberia”, M.G. Levin and LP. Potapov (eds), University of Chicago Press, Chicago.
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McComb, J., Crawford, M.H., Leonard, W.R., Schanfield, M.S., Osipova, L. (1996). Applications of DNA Fingerprints for the Study of Genetic Structure of Human Populations. In: Gustafson, J.P., Flavell, R.B. (eds) Genomes of Plants and Animals. Stadler Genetics Symposia Series. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0280-1_3
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