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Effects of Dietary Taurine on Auditory Function in Full Term Infants

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Taurine 3

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 442))

Abstract

Three groups of neonates fed taurine supplemented infant formula, non-supplemented infant formula or breast milk, respectively, were studied from birth to 12 weeks of age. In addition to the measurement of whole blood taurine content, auditory function was monitored using auditory brainstem responses (ABRs) and transient evoked otoacoustic emissions (TEOAEs). The results showed a significant reduction in whole blood taurine concentration in the non-supplemented formula group. In addition, there was a significant drop in whole blood taurine levels in all 3 groups over the first four weeks of life. ABR wave latencies were significantly shorter in the non-supplemented group, with wave V showing the greatest reductions. Falling taurine levels after full term birth may aid synaptic maturation/efficiency within the auditory system. TEOAE responses were significantly larger over the low to mid frequencies in the breast fed group suggesting improved middle ear function.

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References

  1. Duncan, B., Ey, J., Holberg, C. J., Wright, A. L., Martinez, F. D., and Taussig, L. M., 1993, Exclusive breast feeding for at least 4 months protects against otitis media, Pediatrics, 91:867–872.

    PubMed  CAS  Google Scholar 

  2. Gaull, G. E., Rassin, D. K., Raiha, N. C. R., and Heinonen, K., 1977, Milk protein quantity and quality in low birth weight infants III, Effects on sulfur amino acids in plasma and urine, J. Pediatr. 90:348–355.

    Article  PubMed  CAS  Google Scholar 

  3. Geggel, H. S., Heckenlively, J. R., Martin, D. A., Ament, M. E., and Kopple, J. D., 1982, Human retinal dysfunction and taurine deficiency, Doc. Ophthal. Proc. Ser., 31:199–207.

    Google Scholar 

  4. Hayes, K. C., Carey, R. E., and Schmidt, S. Y., 1975, Retinal degeneration associated with taurine deficiency in the cat, Science, 188:949–951.

    Article  PubMed  CAS  Google Scholar 

  5. Hopkins, P. C., Kay, I. S., and Davies, W. E., 1989, A rapid method for the determination of taurine in biological tissue, Neurochem. Int, 15:429–432.

    Article  PubMed  CAS  Google Scholar 

  6. Imaki, H., Moretz, R., Wisniewski, H., Neuringer, M., and Sturman, J., 1987, Retinal degeneration in 3 month old Rhesus monkey infants fed a taurine free human infant formula, J. Neurosci. Res., 18:602–614.

    Article  PubMed  CAS  Google Scholar 

  7. Jarvenpaa, A-L., Rassin, D. K., Raiha, N. C. R., and Gaull, G. E., 1982, Milk protein quantity and quality in the term infant II, Effects on acidic and neutral amino acids, Pediatrics, 70:221–230.

    PubMed  CAS  Google Scholar 

  8. Kamisaki, Y., Wada, K., Nakamoto, K., and Itoh, T., 1996, Effects of taurine on GABA release from synaptosomes of rat olfactory bulb, Amino Acids, 10:49–57.

    Article  CAS  Google Scholar 

  9. Kontro, P. and Oja, S. S., 1983, Taurine and synaptic transmission, Med. Biol., 61:79–82.

    PubMed  CAS  Google Scholar 

  10. Pasantes-Morales, H. Arzate, N. E., and Cruz, C., 1982, The role of taurine in nervous tissue, its effects on ionic fluxes, in: “Taurine in Nutrition and Neurology” Huxtable, R. J. and Pasantes-Morales, H., eds., Plenum Press, New York, pp. 273–292.

    Chapter  Google Scholar 

  11. Ponton, C. W. and Eggermont, J. J., 1996, Differential development of human ABR III–IV and IV–V intervals: implications for myelination and synaptic maturation, Audiology, 3:109.

    Google Scholar 

  12. Rassin, D. K., Sturman, J. A., and Gaull, G. E., 1978, Taurine and other free amino acids in milk of man and other mammals, Early Hum. Dev., 2:1–13.

    Article  PubMed  CAS  Google Scholar 

  13. Sturman, J. A. and Messing, J. M., 1991, Dietary taurine content and feline reproduction and outcome, J. Nutr., 121:1195–1203.

    PubMed  CAS  Google Scholar 

  14. Sturman, J. A., Rassin, D. K., and Gaull, G. E., 1978, Taurine in the development of the central nervous system, in: “Taurine and Neurological Disorders”, Barbeau, A. and Huxtable, R. J., eds., Raven Press, New York, pp. 49–71.

    Google Scholar 

  15. Tyson, J. E., Laskey, R., Flood, D. Mize, C., Picone, T., and Paule, C. L., 1989, Randomized trial of taurine supplementation for infants ≤ 1,300 gram birth weight: effect on auditory brainstem evoked responses, Pediatrics, 83:406–415.

    PubMed  CAS  Google Scholar 

  16. Usami, S. and Ottersen, O.P, 1995, The localization of taurine-like immunoreactivity in the organ of Corti: a semiquantitative, post-embedding, immunoelectron microscopic analysis in the rat with some observations in the guinea pig, Brain Res., 676:277–284.

    Article  PubMed  CAS  Google Scholar 

  17. Vallecalle-Sandoval, M. H., Heaney, G., Sersen, E., and Sturman, J. A., 1991, Comparison of the developmental changes of the brainstem auditory evoked response (BAER) in taurine supplemented and taurine deficient kittens, Int. J. Dev. Neurol., 9:571–579.

    Article  CAS  Google Scholar 

  18. Vallecalle-Sandoval, M. H., Heaney, G., Sersen, E., and Sturman, J. A., 1993, Comparison of the brainstem auditory evoked response (BAER) in taurine deficient and taurine supplemented cats, Nutr. Res., 13:475–487.

    Article  CAS  Google Scholar 

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© 1998 Springer Science+Business Media New York

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Dhillon, S.K., Davies, W.E., Hopkins, P.C., Rose, S.J. (1998). Effects of Dietary Taurine on Auditory Function in Full Term Infants. In: Schaffer, S., Lombardini, J.B., Huxtable, R.J. (eds) Taurine 3. Advances in Experimental Medicine and Biology, vol 442. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0117-0_61

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  • DOI: https://doi.org/10.1007/978-1-4899-0117-0_61

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-0119-4

  • Online ISBN: 978-1-4899-0117-0

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