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Cerebellar Granule Cell Migration Involves Proteolysis

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Molecular Aspects of Development and Aging of the Nervous System

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 265))

Abstract

Histogenesis in the central nervous system requires extensive cell migration. The migration of granule neurons in the neonatal mouse cerebellum has been a focus of study. Although granule cell migration occurs in close association with Bergmann glial fibers1 and Purkinje cell dendrites2, the actual mechanisms of movement that probably involve cytoskeletal systems as well as the interaction of cell surface and extracellular matrix components remain to be established.

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Author information

Authors and Affiliations

  1. Department of Biochemistry/Biophysics/Genetics, University of Colorado Health Science Center, Denver, Colorado, USA

    Nicholas W. Seeds, Susan Haffke, Kathleen Christensen & Judith Schoonmaker

Authors
  1. Nicholas W. Seeds
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  2. Susan Haffke
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  3. Kathleen Christensen
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  4. Judith Schoonmaker
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Editor information

Editors and Affiliations

  1. The University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA

    Jean M. Lauder

  2. Institute of Biology, INSERM, Montpellier, France

    Alain Privat

  3. Southern Illinois University School of Medicine, Springfield, Illinois, USA

    Ezio Giacobini

  4. University of California, Berkeley, California, USA

    Paola S. Timiras

  5. University of Colorado School of Medicine, Denver, Colorado, USA

    Antonia Vernadakis

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© 1990 Springer Science+Business Media New York

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Seeds, N.W., Haffke, S., Christensen, K., Schoonmaker, J. (1990). Cerebellar Granule Cell Migration Involves Proteolysis. In: Lauder, J.M., Privat, A., Giacobini, E., Timiras, P.S., Vernadakis, A. (eds) Molecular Aspects of Development and Aging of the Nervous System. Advances in Experimental Medicine and Biology, vol 265. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-5876-4_16

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  • DOI: https://doi.org/10.1007/978-1-4757-5876-4_16

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-5878-8

  • Online ISBN: 978-1-4757-5876-4

  • eBook Packages: Springer Book Archive

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