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Abstract

Microglia exhibit at least three morphological and functional states during their life cycle: ameboid, ramified and reactive. Ramified microglia, also called resting microglia, are differentiated cells present in the adult CNS that bear thin ramified processes that emerge from the cell body. Ramified microglial cells are considered inactive in the normal adult CNS. They activate in response to CNS insults to become reactive microglia that retract their processes and upregulate the expression of different molecules (reviewed in Streit et al. (1999); Stoll and Jander (1999)).

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Navascués, J., Cuadros, M.A., Calvente, R., Marín-Teva, J.L. (2002). Roles of Microglia in the Developing Avian Visual System. In: Streit, W.J. (eds) Microglia in the Regenerating and Degenerating Central Nervous System. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-4139-1_2

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