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Metabolism of Myelin

  • Chapter
Myelin

Abstract

By “metabolism of myelin,” we refer to the molecular events involved in the synthesis of myelin components and in the subsequent assembly, maintenance, and turnover of the myelin sheath. The deposition of myelin involves coordination of the synthesis of its various lipid and protein components and the interaction of these components to give a stable membrane. Degradation of myelin components occurs as a reaction of the myelin sheath to injury, but may also be required for normal maintenance and remodeling of the membrane. The topographic features of the myelin sheath can be expected to limit partially the metabolism of myelin. The roles of membrane fluidity and cytoplasmic inclusions in the.turnover of compact myelin lamellae are not well understood, but obviously metabolism in this system is integrally linked to both anatomical and membrane structure.

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Authors and Affiliations

  1. Department of Neurology, School of Medicine Wayne State University, Detroit, Michigan, 48201, USA

    Joyce A. Benjamins

  2. Department of Neurology, Veterans Administration Medical Center, Palo Alto, California, 94304, USA

    Marion E. Smith

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  1. Joyce A. Benjamins
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  2. Marion E. Smith
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Editors and Affiliations

  1. University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

    Pierre Morell

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© 1984 Springer Science+Business Media New York

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Benjamins, J.A., Smith, M.E. (1984). Metabolism of Myelin. In: Morell, P. (eds) Myelin. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1830-0_7

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  • DOI: https://doi.org/10.1007/978-1-4757-1830-0_7

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  • Print ISBN: 978-1-4757-1832-4

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