Abstract
The unit risk has been proposed as a conceptually simple parameter which allows to describe the effect of a carcinogenic substance in low concentration in ambient air to the general population. It is in freqpent use by agencies like the WHO or the EPA. In this paper we describe some models for dose-response analysis and methods for estimating the unit risk and investigate the variability of unit risk estimates as it emerges from using different dose-response analyses and various dataseis. Three substances are investigated, two of which were found to provide a sufficient basis for quantitative risk estimation (arsenic, benzene). The systematic variation of the unit risk estimates was found to be relatively small for both substances.
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Becher, H., Wahrendorf, J. (1990). Variability of Unit Risk Estimates under Different Statistical Models and between Different Epidemiological Data Sets. In: Moolgavkar, S.H. (eds) Scientific Issues in Quantitative Cancer Risk Assessment. Birkhäuser Boston. https://doi.org/10.1007/978-1-4684-9218-7_15
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DOI: https://doi.org/10.1007/978-1-4684-9218-7_15
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