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Gas Transfer through the Skin: A Two-Layer Model Relating Transcutaneous Flux to Arterial Tension

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Oxygen Transport to Tissue — III

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 94))

Abstract

Recent developments in clinical application of transcutaneous blood-gas sensors show promise for continuous, noninvasive monitoring of arterial oxygen and carbon dioxide tensions (Huch et al., 1975). In practice, a probe placed in contact with the skin is used to measure the flux of gas between the skin and the gas space within the probe. The probe or skin electrode is calibrated to relate measured gas flux to arterial tension. Since the flux through the skin depends on many variables an accurate correlation between measured flux and blood-gas tension requires a basic understanding of the overall skin permeation process.

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References

  • Adamczyk, B., Boerboom, A.J., and Kistemaker, J. (1966) J. Appl. Physiol. 21, 1903.

    Article  CAS  Google Scholar 

  • Adams, P.D. (1949) Amer. Perfumer Ess. Oil Rev., 134.

    Google Scholar 

  • Behnke, A.R. and Willmon, T.L. (1941) Amer. J. Physiol. 131, 627.

    Article  CAS  Google Scholar 

  • Collins, J.M., Lambertsen, C.J., and Quinn, J.A. (1976) Physiologist 19, 155.

    Google Scholar 

  • Collins, J.M. (1976) Inert gas transfer in the body: Experimental Study and perfusion/diffusion modeling of transcutaneous and gas cavity exchange rates, Ph.D. Dissertation, University of Pennsylvania.

    Google Scholar 

  • Collins, J.M., Lambertsen, C.J., and Quinn, J.A. (1977) Transcutaneous gas exchange: simultaneous measurement of multiple inert gases. (submitted for publication.)

    Google Scholar 

  • Cullen, B.F. and Eger, E.I. (1972) Anesthesiology 36, 168.

    Article  CAS  Google Scholar 

  • Huch, R., Lubbers, D.W., and Huch, A. (1975) The transcutaneous measurement of oxygen and carbon dioxide tensions for the determination of arterial blood-gas values with control of local perfusion and peripheral perfusion pressure. Theoretical analysis and practical application. In “Oxygen Measurements in Biology and Medicine” p.121 (eds. Payne, J.P. and Hill, D.W.) Butterworths, London and Boston.

    Google Scholar 

  • Klocke, R.A., Gurtner, G.H., and Farhi, L.E. (1963) J. Appl. Physiol. 18, 311.

    Article  CAS  Google Scholar 

  • Michaels, A.S., Chandrasekaran, S.K., and Shaw, J.E. (1975) A.I.Ch.E. Journal 21, 985.

    Article  CAS  Google Scholar 

  • Orcutt, F.S. and Waters, R.M. (1933) Anesthesia and Analgesia 12, 45.

    Article  CAS  Google Scholar 

  • Roughton, F.J.W. (1952) Proc. Roy. Soc. 140B, 203.

    Google Scholar 

  • Scheuplein, R.J. and Blank, I.H. (1971) Physiol. Reviews 51, 702.

    Article  CAS  Google Scholar 

  • Stoelting, R.K. and Eger, E.E. (1969) Anesthesiology 30, 278.

    Article  CAS  Google Scholar 

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© 1978 Plenum Press, New York

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Quinn, J.A. (1978). Gas Transfer through the Skin: A Two-Layer Model Relating Transcutaneous Flux to Arterial Tension. In: Silver, I.A., Erecińska, M., Bicher, H.I. (eds) Oxygen Transport to Tissue — III. Advances in Experimental Medicine and Biology, vol 94. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-8890-6_24

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  • DOI: https://doi.org/10.1007/978-1-4684-8890-6_24

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4684-8892-0

  • Online ISBN: 978-1-4684-8890-6

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