Abstract
Most plants and animals possess a great variety of esterase isozymes of broad substrate specificity and diverse patterns of developmental expression. In the house mouse Mus musculus several loci encoding esterases have been mapped in two clusters on chromosome 8 (Peters, 1982). Some of these loci are very tightly linked and their protein products have similar subunit molecular weights. Similar clusters of apparently homologous loci are found in related species (Peters, 1982), notably the laboratory rat, Rattus norvegicus (Hedrich and von Deimling, 1987), where two clusters are found 17 map units apart on linkage group V. The occurrence of very tightly linked clusters suggests an origin by repeated tandem duplication for some of these esterases. Interestingly, individual members of a cluster are characterised by essentially unique patterns of developmental expression (Peters, 1982; Hedrich and von Deimling, 1987). This implies a relatively rapid alteration of the elements controlling the spatial and temporal expression of these proteins.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Atkinson, P. W., Mills, L. E., Starmer, W. T., and Sullivan, D. T., 1988, Structure and evolution of the Adh genes of Drosophila mojavensis, Genetics 120:713–723.
Baker, W. K., 1980, Evolution of the alpha-esterase duplication within the montana subphylad of the virilis species group of Drosophila, Genetics 94:733–748.
Baker, W. K., and Kaeding, E. A., 1981, Linkage disequilibrium at the alpha-esterase loci in a population of Drosophila montana from Utah, Am. Nat. 117:804–809.
Batterham, P., Chambers, G. K., Starmer, W. T., and Sullivan, D. T., 1984, Origin and expression of an alcohol dehydrogenase gene duplication in the genus Drosophila, Evolution 38:644–657.
Collet, C., Nielsen, K. M., Russell, R. J., Karl, M., Oakeshott, J. G., and Richmond, R. C., 1989, Molecular analysis of duplicated esterase genes in Drosophila melanogaster, Manuscript submitted.
Devonshire, A., 1977, The properties of a carboxylesterase from the peach potato aphid, Myzus persicae (Sulz), and its role in conferring insecticide resistance, Biochem. J. 167:675–683.
East, P. D., 1982, Non-specific esterases of Drosophila buzzatii, in: Ecological Genetics and Evolution: The Cactus-Yeast-Drosophila Model System (J.S.F. Barker, and W.T. Starmer, eds.), Academic Press Australia, Sydney, pp. 323–338
Hall, L. M. C., and Spierer, P., 1986, The Ace locus of Drosophila melanogaster: structural gene for acetylcholinesterase with an unusual 5’ leader, EMBO J. 5:2940–2954.
Hedrich, H. J., and von Deimling, O., 1987, Re-evaluation of LG V of the rat and assignment of 12 carboxylesterases to gene clusters, J. Hered. 78:92–96.
Hultmark, D., Klemenz, R., and Gehring, W. J., 1986, Translational and transcriptional control elements in the untranslated leader of the heat-shock gene hsp22, Cell 44:429–438.
Lewin, B., 1987, Genes III, John Wiley and Sons, New York.
MacPhee-Quigley, K. T., Vedvick, T., Taylor, P., and Taylor, S. S., 1986, Profile of the disulphide bonds in acetylcholinesterase, J. biol. Chem. 260:13565–13570.
Mouches, C., Pasteur, N., Berge, J. B., Hyrien, O., Raymond, M., de Saint Vincent, B. R., de Silvestri, M., and Georghiou, G. P., 1986, Amplification of an esterase gene is responsible for insecticide resistance in a California Culex mosquito, Science 233:778–780.
Myers, M., Richmond, R. C., and Oakeshott, J. G., 1988, On the origins of esterases, Mol. Biol. Evol. 5:113–119.
Oakeshott, J. G., Collet, C., Phillis, R. W., Nielsen, K. M., Russell, R. J., Chambers, G. K., Ross, V., and Richmond, R. C., 1987, Molecular cloning and characterization of esterase-6, a serine hydrolase of Drosophila, Proc. natn. Acad. Sci. USA 84:3359–3363.
Payant, V., Abukashawa, S., Sasseville, M., Benkel, B. F., Hickey, D. A., and David, J., 1988, Evolutionary conservation of the chromosomal configuration and regulation of amylase genes among eight species of the Drosophila melanogaster species subgroup, Mol. Biol. Evol. 5:560–567.
Pen, J., Rongen, H. A. H., and Beintema, J. J., 1984, Purification and properties of Esterase-4 from Drosophila mojavensis, Biochim. biophys. Acta 789:203–209.
Pen, J., Schipper, A., Rongen, H. A. H., and Beintema, J. J., 1986a, Differences in specificity and catalytic efficiency between allozymes of Esterase-4 from Drosophila mojavensis, Mol. Biol. Evol. 3:366–373.
Pen, J., van Beeumen, J., and Beintema, J. J., 1986b, Structural comparison of two esterases from Drosophila mojavensis isolated by immunoaffinity chromatography, Biochem. J. 278:691–699.
Peters, J., 1982, Nonspecific esterases of Mus musculus, Biochem. Genet. 20:585–606.
Sikarov, J-L., Krejci, E., and Massoulie, J., 1987, cDNA sequences of Torpedo marmorata acetylcholinesterase: primary structure of the presursor of a catalytic subunit; existence of multiple 5’-untranslated regions. EMBO J. 6:1865–1873.
Zouros, E., 1973, Genic differentiation associated with the early stages of speciation in the mulleri subgroup of Drosophila, Evolution 27:601.
Zouros, E., and van Delden, W., 1982, Substrate-preference polymorphism at an esterase locus of Drosophila mojavensis, Genetics 100:307–314.
Zouros, E., van Delden, W., Odense, R., and van Dijk, H., 1982, An esterase duplication in Drosophila: Differences in expression of duplicate loci within and among related species, Biochem. Genet. 20:929–942.
Zouros, E., and Krimbas, C. B., 1970, A case of duplication of an esterase locus in the olive fruit fly Dacus oleae, Isozyme Bull. 3:44.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Springer Science+Business Media New York
About this chapter
Cite this chapter
East, P., Graham, A., Whitington, G. (1990). Molecular Isolation and Preliminary Characterisation of a Duplicated Esterase Locus in Drosophila buzzatii. In: Barker, J.S.F., Starmer, W.T., MacIntyre, R.J. (eds) Ecological and Evolutionary Genetics of Drosophila . Monographs in Evolutionary Biology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8768-8_25
Download citation
DOI: https://doi.org/10.1007/978-1-4684-8768-8_25
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-8770-1
Online ISBN: 978-1-4684-8768-8
eBook Packages: Springer Book Archive