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Effects of Cigarette Smoking on Coronary Vascular Dynamics: Relationship to Coronary Atherosclerosis

  • Chapter
Tobacco Smoking and Atherosclerosis

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 273))

Abstract

Substantial evidence has been elucidated regarding the mechanisms that link cigarette smoking with the development and accelerated progression of atherosclerosis. Influences on platelet function, lipid metabolism, coronary artery tone, the sympathetic nervous system, the endocrine system, and oxygen transfer and dissociation from hemoglobin have been identified. The purpose of this chapter is to review previous work outlining the effect of smoking on coronary and systemic hemodynamics, and to discuss how repetitive alterations in vascular tone may be an integral part of the pathway by which smoking leads to an increased risk of coronary atherosclerosis.

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Author information

Authors and Affiliations

  1. Northwestern Memorial Hospital, Chicago, Illinois, USA

    Lloyd W. Klein & Annabelle S. Volgman

  2. Northwestern University Medical School, Chicago, Illinois, USA

    Lloyd W. Klein & Annabelle S. Volgman

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  1. Lloyd W. Klein
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  2. Annabelle S. Volgman
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Editors and Affiliations

  1. Tobacco and Health Research Institute, University of Kentucky, Lexington, Kentucky, USA

    John N. Diana

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© 1990 Plenum Press, New York

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Klein, L.W., Volgman, A.S. (1990). Effects of Cigarette Smoking on Coronary Vascular Dynamics: Relationship to Coronary Atherosclerosis. In: Diana, J.N. (eds) Tobacco Smoking and Atherosclerosis. Advances in Experimental Medicine and Biology, vol 273. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5829-9_30

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  • DOI: https://doi.org/10.1007/978-1-4684-5829-9_30

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5831-2

  • Online ISBN: 978-1-4684-5829-9

  • eBook Packages: Springer Book Archive

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