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Is the Pyriform Cortex Important for Limbic Kindling?

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Kindling 4

Part of the book series: Advances in Behavioral Biology ((ABBI,volume 37))

Abstract

Interest in the contribution of the pyriform cortex to complex partial seizures is not new. In the 1890s Hughlings Jackson and colleagues (9, 10) described a lesion limited to the human uncus, the homologue of the rodent pyriform cortex (2), which they believed initiated ‘uncinate fits’. The development of elaborate behavioral symptoms during the uncinate seizure was presumed to be a result of seizure spread beyond this area, perhaps to the frontal cortex via the uncinate fasciculus (25). Occasionally these spontaneous uncinate seizures developed secondarily into full generalized convulsions, an outcome frequently observed after electrical stimulation of the uncus (21). Thus, it seems that provocation of the uncus is able to directly trigger, or gain access to mechanisms necessary to trigger, secondarily generalized convulsions.

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Authors and Affiliations

  1. Department of Psychology, Carleton University, Ottawa, Ontario, K1S 5B6, Canada

    Dan C. McIntyre & Mary Ellen Kelly

Authors
  1. Dan C. McIntyre
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  2. Mary Ellen Kelly
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Editor information

Editors and Affiliations

  1. Neurosciences and Neurology, University of British Columbia, Vancouver, British Columbia, Canada

    Juhn A. Wada

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© 1990 Plenum Press, New York

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McIntyre, D.C., Kelly, M.E. (1990). Is the Pyriform Cortex Important for Limbic Kindling?. In: Wada, J.A. (eds) Kindling 4. Advances in Behavioral Biology, vol 37. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5796-4_3

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  • DOI: https://doi.org/10.1007/978-1-4684-5796-4_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5798-8

  • Online ISBN: 978-1-4684-5796-4

  • eBook Packages: Springer Book Archive

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