Abstract
In the last few years a number of monoclonal antibodies (MAb) specific for bovine T lymphocytes has been produced. These include antibodies which react with the sheep erythrocyte receptor (designated BoT2) (Davis et al., in press) and thus can be used as pan-T cell markers, and antibodies to the two major subset markers BoT4 and B0T8 (Baldwin et al., 1986; Ellis et al., 1986). When these antibodies are used, in conjunction with reagents that identify B lymphocytes and monocytes, to phenotype bovine leukocytes, there is a residual population of lymphocytes comprising 10–20% of peripheral blood mononuclear cells (PBM) that is unreactive with these reagents. Recently, we have produced a MAb that reacts with a proportion of these “null” lymphocytes. Herein, we will summarise our findings with this antibody.
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References
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© 1988 Plenum Press, New York
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Morrison, W.I., MacHugh, N.D., Bensaid, A., Goddeeris, B.M., Teale, A.J., McKeever, D.J. (1988). A Monoclonal Antibody which Reacts Specifically with a Population of Bovine Lymphocytes Lacking B cell and T cell Markers. In: Fossum, S., Rolstad, B. (eds) Histophysiology of the Immune System. Advances in Experimental Medicine and Biology, vol 237. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5535-9_90
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DOI: https://doi.org/10.1007/978-1-4684-5535-9_90
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