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T Dependent Induction of an IgA and IgM Anti-Polysaccharide Response

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Recent Advances in Mucosal Immunology

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 216 A))

Abstract

The intestinal mucosa is the first site of interaction between the immune system and many foreign antigens and pathogens (1). Major interactions with polysaccharide antigens take place in the gut, and immune responses to bacterial polysaccharides are important in host defenses at mucosal surfaces. Morbidity and mortality from infections with encapsulated bacteria is high in neonates and the elderly. Information regarding how anti-polysaccharide immunity is regulated at mucosal surfaces and changes in that regulation during aging could be of substantial value for strategies to alter anti-polysaccharide immunity and for the design of immunization programs.

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Author information

Authors and Affiliations

  1. Laboratory of Mucosal Immunology Department of Medicine, M-023-D, University of California San Diego, La Jolla, CA, USA

    M. F. Kagnoff & P. D. Murray

Authors
  1. M. F. Kagnoff
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  2. P. D. Murray
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Editor information

Editors and Affiliations

  1. University of Alabama at Birmingham, Birmingham, Alabama, USA

    Jiri Mestecky  & Jerry R. McGhee  & 

  2. McMaster University, Hamilton, Ontario, Canada

    John Bienenstock

  3. State University of New York at Buffalo, Buffalo, New York, USA

    Pearay L. Ogra

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© 1987 Plenum Press, New York

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Kagnoff, M.F., Murray, P.D. (1987). T Dependent Induction of an IgA and IgM Anti-Polysaccharide Response. In: Mestecky, J., McGhee, J.R., Bienenstock, J., Ogra, P.L. (eds) Recent Advances in Mucosal Immunology. Advances in Experimental Medicine and Biology, vol 216 A. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5344-7_18

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  • DOI: https://doi.org/10.1007/978-1-4684-5344-7_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5346-1

  • Online ISBN: 978-1-4684-5344-7

  • eBook Packages: Springer Book Archive

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