Abstract
We have shown that adult rat liver xanthine oxidase exhibits sexual dimorphism.1 Males have greater enzyme activity by comparison to females. The increased enzyme activity in the male corresponds to a greater mass of xanthine oxidase protein.2 Immature animals of both sexes have similar enzyme activity.
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References
D. J. Levinson and D. Chalker, Rat hepatic xanthine oxidase activity: Age and sex specific differences, Arthritis Rheum. 27: 77, 1980.
D. E. Decker and D. J. Levinson, Quantitation of rat liver xanthine oxidase by radioimmunoassay: A mechanism for sex specific differences, Arthritis Rheum. 25: 326, 1982.
C. A. Lamartiniere, C. S. Dieringer, E. Kita, and G. Lucier, Altered sexual differentiation of hepatic uridine diphosphate glucuronyltransferase by neonatal hormone treatment in rats, Biochemistry J. 180: 313, 1979.
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N. P. Illsley and C. A. Lamartiniere, The imprinting of adult hepatic monoamine oxidase levels and androgen responsiveness by neonatal androgens, Endocrinology. 107: 551, 1980.
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© 1984 Plenum Press, New York
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Levinson, D.J., Decker, D.E. (1984). Imprinting by the Neonatal Testis: A Mechanism for Sexual Dimorphism of Rat Liver Xanthine Oxidase. In: De Bruyn, C.H.M.M., Simmonds, H.A., Müller, M.M. (eds) Purine Metabolism in Man-IV. Advances in Experimental Medicine and Biology, vol 165. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4553-4_100
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DOI: https://doi.org/10.1007/978-1-4684-4553-4_100
Publisher Name: Springer, Boston, MA
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