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Multinucleation and Polyploidization of Aging Human Cells in Culture

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Aging Phenomena

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 129))

Abstract

Multinucleated cells and polyploid cells appear widely in liver, salivary glands, and other mammalian organs. In liver, the multi-nucleation and polyploidization of hepatocytes are the functions of development, nutrition, regeneration and aging (1,2,3,4). A schematic genealogy of cells has been proposed for the development of multinucleation and polyploidization in rodent liver (2).

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© 1980 Plenum Press, New York

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Matsumura, T. (1980). Multinucleation and Polyploidization of Aging Human Cells in Culture. In: Oota, K., Iriki, M., Makinodan, T., Baker, L.S. (eds) Aging Phenomena. Advances in Experimental Medicine and Biology, vol 129. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3734-8_4

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  • DOI: https://doi.org/10.1007/978-1-4684-3734-8_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3736-2

  • Online ISBN: 978-1-4684-3734-8

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