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Content of Stable Strontium in Man and Animal Biota

  • Chapter
Handbook of Stable Strontium

Abstract

Until the atomic era Sr2+ was of limited biological interest, being used primarily to remove traces of gas from vacuum tubes and to impart red color for tracer bullets, signal rockets, flares, and fireworks (1). To a limited degree Sr2+ compounds are also used in ceramics, drugs, greases, and special iron compositions. In 1968 a mere 12,500 tons of Sr2+ were produced in the free world (2). The advent of radioactive Sr2+, a fission product of nuclear reaction, presented a radiological hazard to the biosphere because of its long half-life (28 years), its affinity for deposition in bone, and its similarity to Ca2+. The voluminous literature concerning radiological effects of90 Sr, its distribution in the biosphere and transport through the food chain, and the dynamics of Sr2+ metabolism in man, lower animals, and plants significantly contributed to our knowledge of the naturally occurring stable element, although their effects have nothing in common except affinity to bone.

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References

  1. G. A. P. Wyllie, The strontian mines, in: Strontium Metabolism (J. M. A. Lenihan, J. F. Loutit, and J. H. Martin, eds.), pp. 13–15, Academic Press, London (1967).

    Google Scholar 

  2. Mineral Facts and Problems, U.S. Department of Interior, Bureau of Mines, U.S. Government Printing Office, Washington (1970).

    Google Scholar 

  3. B. Mason, Principles of Geochemistry, 2nd ed., John Wiley, New York (1958).

    Google Scholar 

  4. H. J. M. Bowen, Trace Elements in Biochemistry, Academic Press, London (1966).

    Google Scholar 

  5. H. L. Rosenthal, M. M. Eves, and O. A. Cochran, Common strontium of mineralized tissues from marine and sweet water animals. Comp. Biochem. Physiol. 32, 445–450 (1970).

    Article  CAS  Google Scholar 

  6. H. A. Schroeder, I. H. Tipton, and A. P. Nason, Trace metals in man: strontium and barium. J. Chron. Dis 25, 491–517 (1972).

    Article  CAS  Google Scholar 

  7. K. K. Turekian, R. C. Harriss, and D. G. Johnson, The variation of Sr, CI, Na, Ca, Sr, Ba, Co, and Ag in Neuse River, North Carolina. Limnol. Oceanogr. 12, 702–706 (1967).

    Article  CAS  Google Scholar 

  8. C. M. Durfor and E. Becher, Public Water Supplies of 100 largest cities in the United States, Geological Survey Water Supply Paper 1812, U.S. Dept. Interior, U.S. Government Printing Office, Washington (1963).

    Google Scholar 

  9. G. Faure, J. H. Crocket, and P. M. Hurley, Some aspects of the geochemistry of strontium and calcium in the Hudson Bay and the Great Lakes. Geochim. Cosmochim. Acta 31:451–461 (1967).

    Article  CAS  Google Scholar 

  10. I. L. Ophel and J. M. Judd, Skeletal distribution of strontium and calcium and strontium: calcium ratios in several species of fish, in: Strontium Metabolism (J. M. A. Lenihan, J. F. Loutit, and J. H. Martin, eds.) pp. 103–109, Academic Press, London (1967).l

    Google Scholar 

  11. H. U. Sverdrup, M. W. Johnson, and R. H. Fleming, The Oceans, Prentice Hall, New York (1942).

    Google Scholar 

  12. W. Slavin, W. Atomic Absorption Spectroscopy, Wiley Interscience, New York (1968).

    Google Scholar 

  13. T. J. Chow and T. G. Thompson, Flame photometric determination of strontium in sea water. Analyt. Chem. 27, 18–21 (1955).

    Article  CAS  Google Scholar 

  14. E. E. Angino, G. K. Billings, and N. Anderson, Observed variations in the strontium concentration of sea water. Chem. Geol. 1, 145–153 (1966).

    Article  CAS  Google Scholar 

  15. F. T. Mackenzie, Strontium content and variable strontium-chlorinity relationship of Sargasso Sea Water. Science 146, 517–518 (1964).

    Article  CAS  Google Scholar 

  16. N. R. Andersen and D. N. Hume, The strontium and barium content of sea water, in: Trace Inorganics In Water, Advances in Chemistry, Series 73 (J. F. Gould, ed.), pp. 296–307, American Chemical Society, Washington (1967).

    Google Scholar 

  17. H. L. Rosenthal, O. A. Cochran, and M. M. Eves, Strontium content of mammalian bone, diet and excreta. Environ. Resch. 5, 182–191 (1972).

    Article  CAS  Google Scholar 

  18. A. Gormican, Inorganic Elements in Foods Used in Hospital Menus. J. Amer. Diet. Ass. 56, 397–403(1970).

    CAS  Google Scholar 

  19. F. J. Bryant and J. F. Loutit, The entry of strontium-90 into human bone. Proc. Royal Soc. Ser. B 159,449–465(1964).

    Article  CAS  Google Scholar 

  20. G. L. Rehnberg, A. B. Strong, C. R. Porter, and M. W. Carter, Levels of stable strontium in milk and the total diet. Environ. Sci. Tech. 3, 171–173 (1969).

    Article  CAS  Google Scholar 

  21. J. Rivera, Fallout Program Quarterly Summary Report HASL-146, New York, U.S. Atomic Energy Commission Health and Safety Lab (1964).

    Google Scholar 

  22. I. H. Tipton, P. L. Stewart, and P. G. Martin, Trace elements in diets and excreta. Health Phys. 12, 1683–1689(1966).

    Article  CAS  Google Scholar 

  23. V. A. Knizhnikov and A. N. Marei, Strontium metabolism in man, in: Strontium Metabolism (J. M. A. Lenihan, J. F. Loutit, and J. H. Martin, eds.), pp. 71–82, Academic Press, London (1967).

    Google Scholar 

  24. L. T. Steadman, F. Brudevold, and F. A. Smith, Distribution of strontium in teeth from different geographic areas. J. Amer. Dent. Assoc. 57:340–344(1958).

    CAS  Google Scholar 

  25. V. R. Bohman, C. Blincoe, M. A. Wade, A. L. Lesperance, and E. L. Fountain, Accumulation of strontium in bovine bones. J. Agri. Food Chem. 14, 413–415 (1966).

    Article  CAS  Google Scholar 

  26. G. E. Harrison, A. Sutton, H. Shepherd, and E. M. Widdowson, Strontium balance in breast-fed babies. Brit. J. Nutr. 19, 111–117 (1965).

    Article  CAS  Google Scholar 

  27. W. L. Templeton and V. M. Brown, The relationship between the concentrations of calcium, strontium and strontium-90 in wild trout, Salmo trutta L. and the concentrations of the stable elements in some waters of the United Kingdom and the implications in radiological health studies. Inter. J. Air Water Pollut. 8, 49–75 (1964).

    CAS  Google Scholar 

  28. T. E. Denton and J. C. O’Kelley, Algae as nutrient material for studying Ca-Sr relationship in Heterotrophic organisms. Nature (London) 227, 1161–1163 (1970).

    Article  CAS  Google Scholar 

  29. E. Lloyd, A comparison of the metabolism of calcium and strontium in rabbit and man, in: Strontium Metabolism (J. M. A. Lenihan, J. F. Loutit, and J. H. Martin, eds.), pp. 167–173, Academic Press, London (1967).

    Google Scholar 

  30. G. C. Fariss, Factors influencing the accumulation of strontium-90, stable strontium and calcium in mule deer, U. S. National Technical Information Service Paper No. C00–1156–26 (1967).

    Google Scholar 

  31. R. M. Hodges, N. S. MacDonald, R. Nusbaum, R. Stearns, F. Ezmirlian, P. Spain, and C. McArthur, The strontium content of human bones. J. Biol. Chem. 185, 519–524 (1950).

    CAS  Google Scholar 

  32. W. M. B. Roberts, Estimation of strontium in animal bone using x-ray fluorescence analysis. Nature (London) 183, 887–888 (1959).

    Article  CAS  Google Scholar 

  33. E. M. Sowden and S. R. Stitch, Trace elements in human tissue. 2. Estimation of the concentrations of stable strontium and barium in human bone. Biochem. J. 67, 104–109 (1957).

    CAS  Google Scholar 

  34. K. K. Turekian and J. L. Kulp, Strontium content of human bones. Science 124, 405–407 (1956).

    Article  CAS  Google Scholar 

  35. D. L. Thurber, J. L. Kulp, E. Hodges, P. M. Gast, and J. M. Wampler, Common strontium content of the human skeleton. Science 128, 256–257 (1958).

    Article  CAS  Google Scholar 

  36. M. M. Golutvina, A. Kuznetzov, N. Ya. Novikova, and Ya. M. Nikolaer, Determination of strontium in human bone. Lab. Delo. (Russ.) 11, 660–670 (1967).

    Google Scholar 

  37. I. Rytomaa, L. Kolehmainen, and H. Tuompo, Strontium content of deciduous teeth in northern and southern Finland. Acta. Odont. Scand. 33, 115–118 (1975).

    Article  CAS  Google Scholar 

  38. D. H. Retief, P. E. Cleaton-Jones, J. Turkstra, and W. J. deWet, The quantitative analysis of Sr, Au, Br, Mn and Na in normal human enamel and dentine by neutron activation and high resolution gamma spectrometry. J. Dent. Assoc. S. Afr. 26, 63–69 (1970).

    Google Scholar 

  39. F. L. Losee, M. E. J. Curzon, and M. F. Little, Trace element concentrations in human enamel. Arch. Oral. Biol. 19, 467–470(1974).

    Article  CAS  Google Scholar 

  40. N. Wolf, I. Gedalia, S. Yariv, and H. Zuckermann, The strontium content of bones and teeth of human faetuses. Arch. Oral Biol. 17, 93–109 (1973).

    Google Scholar 

  41. N. Miyao, Strontium metabolism following strontium-calcium discrimination factor in domestic animals. Nippon Juigaku Zasshi 22, 273–286 (1960).

    Article  CAS  Google Scholar 

  42. N. B. Price and A. Hallam, A Variation of Sr content within shells ofrecent Nautilus and Sepia. Nature (London) 215, 1272–1274 (1967).

    Article  CAS  Google Scholar 

  43. R. W. G. Wychoff and A. R. Doberenz, The strontium content of fossil teeth and bone. Geochim. Acta 32, 109–115(1968).

    Article  Google Scholar 

  44. H. A. Lowenstam, in: The Earth Sciences: Problems and Progress in Current Research, No. 137 (T. W. Donnlly, ed.), University Chicago Press (1963).

    Google Scholar 

  45. A. Hallam and N. B. Price, Strontium contents of recent and fossil aragonitic cephalopod shells. Nature (London) 212, 25–27 (1966).

    Article  CAS  Google Scholar 

  46. P. C. Ragland, O. H. Pilkey, and B. W. Blackwelder, Comparison of the Sr/ Ca ratio of fossil and recent mollusc shells. Nature (London) 224, 1223–1224 (1969).

    Article  CAS  Google Scholar 

  47. A. S. Posner, Crystal chemistry of bone mineral. Physiol. Rev. 49, 760–792 (1969).

    CAS  Google Scholar 

  48. I. H. Tipton and M. J. Cook, Trace elements in human tissues. II. Adult subjects from the United States. Health Phys. 9, 103–145 (1963).

    Article  CAS  Google Scholar 

  49. W. E. C. Wacher and B. L. Vallee, Nucleic acids and metals. I. Chromium, manganese, nickel, iron and other metals in ribonucleic acid from diverse biological sources. J. Biol. Chem. 234, 3257–3262(1959).

    Google Scholar 

  50. H. L. Rosenthal and O. A. Cochran, Binding of85 Sr to homogenate and subcellular fractions of rabbit tissues. Proc. Soc. Exper. Biol. Med. 141, 850–856 (1972).

    CAS  Google Scholar 

  51. H. L. Rosenthal, Accumulation of strontium-90 and Ca-45 by fresh water fishes. Proc. Soc. Exp. Biol. Med. 104, 88–91 (1960).

    CAS  Google Scholar 

  52. H. Boroughs, S. J. Townsley, and R. W. Hiatt, The metabolism of radionuclides by marine organisms. III. The uptake of calcium-45 in solution by marine fish. Limnol. Oceanogr. 2, 28–32 (1957).

    Article  Google Scholar 

  53. S. A. Lough, J. Rivera, and C. L. Cornar, Retention of strontium, calcium and phosphorus in human infants. Proc. Soc. Exp. Biol. Med. 112, 631–636 (1963).

    CAS  Google Scholar 

  54. H. L. Rosenthal, J. T. Bird, and J. E. Gilster, Strontium-90 content of first bicuspids. Nature (London) 210, 210–212 (1966).

    Article  CAS  Google Scholar 

  55. C. L. Cornar, R. H. Wasserman, and M. M. Nold, Strontium-calcium discrimination factors in the rat. Proc. Soc. Exper. Biol. Med. 92, 859–863 (1956).

    Google Scholar 

  56. C. L. Cornar and F. Bronner, Mineral Metabolism, Vol. IIA Academic Press, New York (1964).

    Google Scholar 

  57. H. Spencer, M. Li, J. Samachson, and D. Lazio, Metabolism of strontium-85 and calcium-45 in man. Metabolism 9, 916–925 (1960).

    CAS  Google Scholar 

  58. C. L. Cornar, Some principles of strontium metabolism: implications, applications, limitations, in: Strontium Metabolism (J. M. A. Lenihan, J. F. Noutit, and J. F. Martin, eds.), pp. 17–31, Academic Press, London (1967).

    Google Scholar 

  59. M. Walser and B. H. B. Robinson, Renal excretion and tubular reabsorption of calcium and strontium, in: The Transfer of Calcium and Strontium Across Biological Membranes (R. H. Wasserman, ed.), pp. 305–326, Academic Press, New York (1963).

    Google Scholar 

  60. H. L. Rosenthal, Uptake, turnover and transport of bone seeking elements in fishes. Ann. N. Y. Acad. Sci. 109, 278–293 (1963).

    Article  CAS  Google Scholar 

  61. H. L. Rosenthal, The metabolism of strontium-90 and calcium-45 by Lebistes. Biol. Bull. 113, 442–450(1957).

    Article  CAS  Google Scholar 

  62. H. L. Rosenthal, Uptake and turnover of calcium-45 by the guppy, Science 124, 571–574(1956).

    Article  CAS  Google Scholar 

  63. H. L. Rosenthal, Uptake of calcium-45 and strontium-90 from water by fresh-water fishes. Science 126, 599–700(1957).

    Article  Google Scholar 

  64. E. Storey, Calcium and strontium changes in bone associated with continuous administration of stable strontium to rats. Arch. Biochem. Biophys. 103, 575–581 (1968).

    Article  Google Scholar 

  65. C. W. Weber, A. R. Doberenz, and B. L. Reid, Strontium metabolism in mature hens and growing embryos. Poultry Sc., 52, 1472–1473 (1973).

    CAS  Google Scholar 

  66. N. S. MacDonald, F. Ezmirlian, P. Spain, and C. McArthur, The ultimate site of skeletal deposition of strontium and lead. J. Biol. Chem. 189, 387–399 (1951).

    CAS  Google Scholar 

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Authors and Affiliations

  1. Washington University School of Dental Medicine, St. Louis, Missouri, USA

    Harold L. Rosenthal

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  1. Harold L. Rosenthal
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Editors and Affiliations

  1. McGill University and St. Mary’s Hospital Center, Montreal, Quebec, Canada

    Stanley C. Skoryna

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© 1981 Plenum Press, New York

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Rosenthal, H.L. (1981). Content of Stable Strontium in Man and Animal Biota. In: Skoryna, S.C. (eds) Handbook of Stable Strontium. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3698-3_30

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  • DOI: https://doi.org/10.1007/978-1-4684-3698-3_30

  • Publisher Name: Springer, Boston, MA

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