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Human Experiences Related to Adverse Drug Reactions to the Fetus or Neonate from Some Maternally Administered Drugs

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Drugs and Fetal Development

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 27))

Abstract

Life is a continuous process; a live ovum and spermatozoon unite to form a human being like, yet not identical, with any other member of the species. These host differences offer opportunity for variability in reaction to a noxious drug. The life span — from conception to old age — is divided biologically and on other grounds into quite different periods rather clearly separated from each other. This presents another host basis for variability to a drug’s effects.

Revised from: Shirkey, H.C. (Ed.), Pediatric Therapy (4th ed.) 1972, C.V. Mosby Co., St. Louis, Mo.

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References

  1. WARKANY, J. Drugs and teratology, p. 132. In: Pediatric Therapy (4th ed.) Shirkey, H.C. (ed.), C. V. Mosby Co., St. Louis, Mo. 1972.

    Google Scholar 

  2. WILSON, J.G. AND WARKANY, J. Editors. Teratology: principles and techniques. Chicago, 1965, University of Chicago Press.

    Google Scholar 

  3. Ibid. p. 185.

    Google Scholar 

  4. EDITORIAL. Brit. Med. J. 1: 642, 1970.

    Article  Google Scholar 

  5. DIPAOLO, J.A. KOTIN, P. Arch. Path. 81: 3, 1966.

    PubMed  CAS  Google Scholar 

  6. SHOTTON, D. E1 MONIE, I.W. J.A.M.A. 186:74, 1963.

    Google Scholar 

  7. WERBOFF, J. GOTTLIEB,J.S. Obstet. Gynec. Survey 18: 420, 1963.

    Article  Google Scholar 

  8. McKHANN, G.M. YAFFE, S.J. Drugs and poisons in relation to the developing nervous system. Proceedings of the Conference on Drugs and Poisons as Etiologic Agents in Mental Retardation, Feb. 26-March 1, 1967. Palo Alto, Calif. and Bethesda, Md., U.S. Department of Health, Education and Welfare.

    Google Scholar 

  9. HORSTMANN, W. Z. Kinderheizk. 96: 291, 1966.

    Article  CAS  Google Scholar 

  10. APGAR, V. J.A.M.A. 190: 840, 1964.

    Article  PubMed  CAS  Google Scholar 

  11. BAKER, J.B. PharmacoZ. Rev. 12: 37, 1960.

    CAS  Google Scholar 

  12. NYHAN, W.L. J. Pediat., 59:1 1961.

    Google Scholar 

  13. LUCEY, J.F. Pediat. Clin. N. Amer. 8: 413, 1961.

    PubMed  CAS  Google Scholar 

  14. MOYA, F. THORNDIKE, V. Amer. J. Obstet. Gynec. 84: 1778, 1962.

    PubMed  CAS  Google Scholar 

  15. MONTAGU, A. Prenatal influences, Springfield, Ill., 1962, Charles C. Thomas, Publisher.

    Google Scholar 

  16. WILSON, M.G. Amer. J. Obstet. Gynec. 83: 818, 1962.

    PubMed  CAS  Google Scholar 

  17. BLACK, J.A. Practitioner189:991962.

    Google Scholar 

  18. MAY, C.D., editor: Perinatal pharmacology, Report on the Forty-first Ross Conference on Pediatric Research, Columbus, Ohio, 1962, Ross Laboratories.

    Google Scholar 

  19. Report: Conference on prenatal effects of drugs. March 2930, 1963, Chicago, 1963, Commission on Drug Safety.

    Google Scholar 

  20. COHLAN, S.Q. New York J. Med. 64: 493, 1964.

    PubMed  CAS  Google Scholar 

  21. DONE, A.K. Clin. Pharmacol. Ther. 5: 432, 1964.

    PubMed  CAS  Google Scholar 

  22. ARENA, J.M. Clin. Pediat. 3: 450, 1964.

    Article  PubMed  CAS  Google Scholar 

  23. WARKANY, J KALTER, H. Etiology and prevention of congenital malformations, Proceedings of the Bi-regional Institute on Maternity Care - Primary prevention, Berkeley, Calif., June 21–25, 1964, Univ. of Calif. School of Pub. Health.

    Google Scholar 

  24. SUTHERLAND, J.M. LIGHT, I. J. Pediat. Clin. N. Amer. 12: 781, 1965.

    CAS  Google Scholar 

  25. ROBSON, J.M., SULLIVAN, F.M. SMITH, R.L., editors: A symposium on embryopathic activity of drugs, Boston, 1965, Little, Brown Co.

    Google Scholar 

  26. WOOLLAM, D.H.M., editor: Advances in teratology, Vol. 1, London, 1966. Logos Press, Ltd.

    Google Scholar 

  27. NORA, J.J., NORA, A.H. SOMMERVILLE, R.J., ET AL. J.A.M.A. 202: 1065, 1967.

    Article  PubMed  CAS  Google Scholar 

  28. SHEPARD, T.H. HOLLINGSWORTH, R.R. (Letters to the editor), Pediatrics 42: 713, 1968.

    PubMed  CAS  Google Scholar 

  29. KALLEN, B. WINBERG, J. Pediatrics 41: 765, 1968.

    PubMed  CAS  Google Scholar 

  30. SHIRKEY, H.C. Adverse reactions to drugs - their relation to growth and development, p. 139 in Shirkey, H.C. (ed.) Pediatric Therapy (4th ed.), 1972, C. V. Mosby Co., St. Louis, Mo.

    Google Scholar 

  31. THIERSCH, J.B. Amer. J. Obstet. Gynec. 63: 1298, 1952.

    PubMed  CAS  Google Scholar 

  32. MELTZER, H.J. J.A.M.A. 161: 1253, 1956.

    Article  CAS  Google Scholar 

  33. WARKANY, J., BEAUDRY, P.H. F, HORNSTEIN, S. Amer. J. Dis. Child. 97: 274, 1959.

    CAS  Google Scholar 

  34. SOKAL, J.E. LESSMANN, E.M. J.A.M.A. 172: 1765, 1960.

    Article  CAS  Google Scholar 

  35. EMERSON, D.J. Amer. J. Obstet. Gynec. 84: 356, 1962.

    CAS  Google Scholar 

  36. SHAW, E.B. STEINBACK, H.L. Amer. J. Dis. Child. 115: 477, 1968.

    PubMed  CAS  Google Scholar 

  37. NICHOLSON, H.O. J. Obstet. Gynaec. Brit. Comm. 75: 307, 1968.

    Article  PubMed  CAS  Google Scholar 

  38. TAKATA, A. Hosp. Form. Manage. 4: 25, 1969.

    Google Scholar 

  39. MILUNSKY, A., GRAEF, J.W. GAYNOR, M.F., JR. J. Pediat. 72: 790, 1968.

    Article  PubMed  CAS  Google Scholar 

  40. CURLESS, R.G. (Letter to the editor). New Eng. J. Med. 285: 296, 1971.

    PubMed  CAS  Google Scholar 

  41. DIAMOND, I., ANDERSON, M.M. McCREADIE, S.R. Pediatrics 25: 85, 1960.

    PubMed  CAS  Google Scholar 

  42. GREENBERG, L.H. TANAKA, K.R. J.A.M.A. 188: 423, 1964.

    Article  PubMed  CAS  Google Scholar 

  43. SHERMAN, J.L., JR. LOCKE, R.V. New Eng. J. Med. 259: 288, 1958.

    Article  PubMed  Google Scholar 

  44. WHITE, L.G. J.A.M.A. 179: 973, 1962.

    Article  PubMed  CAS  Google Scholar 

  45. SMITH, R.B., SHEEHY, T.W. ROTHBERT, H. Arch. Intern. Med. 102: 777, 1958.

    Article  CAS  Google Scholar 

  46. DUGDALE, M. FORT, A.T. J.A.M.A. 299: 131, 1967.

    Article  Google Scholar 

  47. ROSENZWEIG, A.I., CREWS, Q.E., JR. HOPWOOD, H.C. Ann. Intern. Med. 6Z: 108, 1964.

    Google Scholar 

  48. MACHADO, J.P. (Letter). J.A.M.A. 201: 126, 1967.

    Article  Google Scholar 

  49. SHIRKEY, H.C. Ann. Intern. Med. 61: 162, 1964.

    PubMed  CAS  Google Scholar 

  50. MACKLER, B. Pediatrics 43: 915, 1969.

    PubMed  CAS  Google Scholar 

  51. YOUNG, J.B. Hosp. Form. Manage. 4: 13, 1969.

    Google Scholar 

  52. KARNOFSKY, D.A. Ann. Rev. PharmacoZ. 5: 447, 1965.

    Article  CAS  Google Scholar 

  53. NISHIMURA, H. Chemistry and prevention of congenital anomalies. Springfield, Ill., 1964, Charles C. Thomas, Publisher.

    Google Scholar 

  54. WARKANY, J. G KALTER, H. New Eng. J. Med. 265:993, 1046

    Google Scholar 

  55. MELLIN, G.W. KATZENSTEIN, M. New Eng. J. Med. 267:1184

    Google Scholar 

  56. LENZ, W. Amer. J. Dis. Child. 112: 99, 1966.

    PubMed  CAS  Google Scholar 

  57. GOLD, W. MICHAEL, A.F., JR. J. Pediat. 52: 279, 1958.

    Article  PubMed  CAS  Google Scholar 

  58. GRUMBACH, M.M. DUCHARME, J.R. Fertil. Steril. 11: 157, 1960.

    PubMed  CAS  Google Scholar 

  59. WILKINS, L. J.A.M.A. 172: 1028, 1960.

    Article  CAS  Google Scholar 

  60. BONGIOVANNI, A.M., DI GEORGE, A.M. GRUMBACK, M.M. J. Clin. Endocr. 19: 1004, 1959.

    Article  Google Scholar 

  61. VOORHESS, M.L. J. Pediat. 72: 128, 1967.

    Google Scholar 

  62. JACOBSON, B.D. Amer. J. Obstet. Gynec. 84: 962, 1962.

    Google Scholar 

  63. BURSTEIN, R. WASSERMAN, H.C. Obstet. Gynec. 23: 931, 1964.

    PubMed  CAS  Google Scholar 

  64. FORTUNOFF, S., LATTIMER, J.K. EDSON, M. Surg. Gynec. Obstet. 118: 545, 1964.

    PubMed  CAS  Google Scholar 

  65. GLENISTER, T.W. HAMILTON, W.J. J. Obstet. Gynaec. Brit. Comm. 70: 13, 1963.

    Article  CAS  Google Scholar 

  66. MOSER, R.H., editor: Diseases of medical progress: a study of iatrogenic diseases. ed. 3, Springfield, Ill., 1969, Charles C. Thomas, Publisher.

    Google Scholar 

  67. BREIBART, S., BONGIOVANNI, A.M. EBERLEIN, W.R. New Eng. J. Med. 268: 255, 1963.

    Article  PubMed  CAS  Google Scholar 

  68. GOLDZICHER, J.W. RODGERS, K. Amer. J. Obstet. Gynec. 86: 882, 1963.

    Google Scholar 

  69. MORTON, W.R.M. Development of the urogenital system. In Rashad, M.N. and Morton, W.R.M., editors: Selected topics on genital anomalies and related subjects. Springfield, Ill., 1969, Charles C. Thomas, Publisher.

    Google Scholar 

  70. American Hospital Formulary Service, American Society of Hospital Pharmacists, Washington, D.C. (continuing). 70a. FOLKMAN, J. (Editorial) New Eng. J. Med. 285: 404, 1971.

    Article  Google Scholar 

  71. BERNHARD, W.G., GRUBIN, H. SCHELLER, G.A. Arch. Path. 60: 635, 1955.

    CAS  Google Scholar 

  72. BONGIOVANNI, A.M. EBERLEIN, W.R., THOMAS, P.Z. ET AL. J. Clin. Endocr. 16: 146, 1956.

    Article  PubMed  CAS  Google Scholar 

  73. PETTY, C.S. BENEDETTO, R.L. New Eng. J. Med. 256: 1103, 1957.

    Article  PubMed  CAS  Google Scholar 

  74. GALINA, M.P., AVNET, N.L. EINHORN, A. New Eng. J. Med. 267: 1124, 1962.

    Article  PubMed  CAS  Google Scholar 

  75. MARTIN, M.M. RENTO, R.D. J. Pediat. 61: 94, 1962.

    Article  PubMed  CAS  Google Scholar 

  76. BLACK, J.A. Arch. Dis. Child. 38: 526, 1963.

    Article  PubMed  CAS  Google Scholar 

  77. LOUW, J.H. S. Afr. Med. J. 37: 976, 1963.

    PubMed  CAS  Google Scholar 

  78. ANDERSON, G.S. BIRD, T. Lancet 2: 742, 1964.

    Google Scholar 

  79. CROUGHS, W. VISSER, H.K.A. J. Pediat. 67: 353, 1965.

    Article  PubMed  CAS  Google Scholar 

  80. IHASSAN, A.I., AREF, G.H. KASSEM, A.S. Arch. Dis. Child. 43: 702, 1968.

    Article  Google Scholar 

  81. WOLFF, J. Amer. J. Med. 47: 101, 1969.

    Article  PubMed  CAS  Google Scholar 

  82. AARON, H. Med. Lett. Drugs Ther. 12: 1, 1970.

    Google Scholar 

  83. McKAY, R.J. The fetus and newborn infant. In Nelson, W.E., Vaughan, V.C., III, and McKay, R.J., editors: Textbook of pediatrics, ed. 9, Philadelphia, 1969. W.B. Saunders Co.

    Google Scholar 

  84. VAN WYK, J.J. The thyroid. In Barnett, Ji.L., Einhorn, A.H. editors: Pediatrics, ed. 14, New York, 1968, AppletonCentury-Crofts.

    Google Scholar 

  85. RUSSELL, K.P., ROSE, H., STARR, P. Surg. Gynec. Obstet. 104: 560, 1957.

    PubMed  CAS  Google Scholar 

  86. FISHER, W.D., VOORHESS, M.L. GARDNER, L.I. J. Pediat. 62: 132, 1963.

    Article  PubMed  CAS  Google Scholar 

  87. HAMILL, G.C., JARMAN, J.A., WYNNE, M.D. Amer. J. Obstet. Gynec. 81: 1018, 1961.

    PubMed  CAS  Google Scholar 

  88. SHAPIRO, R. N. Eng. J. Med. 264: 378, 1961.

    Article  CAS  Google Scholar 

  89. HONE, G.M. MAGAREY, I. Med. J. Aust. 2: 524, 1948.

    PubMed  CAS  Google Scholar 

  90. HEPNER, W.R., JR. Amer. J. Obstet. Gynec. 63: 869, 1952.

    PubMed  Google Scholar 

  91. ELPHINSTONE, N. Lancet 2: 1281, 1953.

    Article  Google Scholar 

  92. AARON, H.H., SCHNEIERSON, S.J., SIEGEL, E. J.A.M.A. 159: 848, 1955.

    Article  CAS  Google Scholar 

  93. BURROW, G.W. J. Clin. Endocr. 25: 403, 1965.

    Article  PubMed  CAS  Google Scholar 

  94. BURROW, G.N., BARTSOCAS, C., KLATSKIN, E.H., ET AL. Am. J. Dis. Child. 216: 161, 1968.

    Google Scholar 

  95. MACDONALD, A. J. Obstet. Gynaec. Brit. Emp. 4: 240, 1903.

    Google Scholar 

  96. SENIOR, B. CHERNOFF, H.L. Pediatrics 47: 510, 1971.

    PubMed  CAS  Google Scholar 

  97. BECKMAN, H., editor: Year book of drug therapy 1964–1965, Chicago, 1965, Year Book Medical Publishers, Inc.

    Google Scholar 

  98. SISSON, J.C. J. Nucl. Med. 6: 853, 1965.

    PubMed  CAS  Google Scholar 

  99. YAMAZAKI, E., NOGUCHI, A. SLINGERLAND, D.W. J. Clin. Endocr. 29: 1437, 1959.

    Article  Google Scholar 

  100. CHAPMAN, E.M., CORNER, G.W., ROBINSON, D., ET AL. J. Clin. Endocr. 8: 717, 1948.

    Article  PubMed  CAS  Google Scholar 

  101. CARAKUSHANSKY, G., CARDENAS, L.E. GARDNER, L.I. Pediatrics 44: 1020, 1969.

    PubMed  CAS  Google Scholar 

  102. NYHAN, W.L. LAMPERT, F. Anesthesiology 26: 487, 1965.

    Article  PubMed  CAS  Google Scholar 

  103. STANBURY, J.B. DEGROOT, L. J. New Eng. J. Med. 271: 195, 1964.

    Article  CAS  Google Scholar 

  104. CANTOLINO, S.J., SCHMICKEL, R.D., BALL, M., ET AL. New Eng. J. Med. 275: 739, 1966.

    Article  PubMed  CAS  Google Scholar 

  105. EDITORIAL, New Eng. J. Med. 275: 786, 1966.

    Article  Google Scholar 

  106. DAWSON, K.P. Brit. Med. J. 2: 112, 1970.

    Article  PubMed  CAS  Google Scholar 

  107. JELLIFFE, R.W., HILL, D., TATTER, D. ET AL. J.A.M.A. 208: 1846, 1969.

    Article  Google Scholar 

  108. DIDING, N., OTTOSSON, J.O. SCHOU, M. Acta Psychiat. Scand. supp. 207, 1969.

    Google Scholar 

  109. PAPE, K.S. VAN BEUSEKOM, J.A.L. Adverse reaction titles, vol. 3. Amsterdam. 1968, Excerpta Medica Foundation.

    Google Scholar 

  110. SHOPSIN, B. Dis. Nerv. Syst. 31: 237, 1970.

    PubMed  CAS  Google Scholar 

  111. GREENFIELD, I., ZUGER, M., BLEAK, R.M., ET AL. New York J. Med. 50: 459, 1950.

    PubMed  CAS  Google Scholar 

  112. SCHOU, M., BAASTRUP, P.G., GROF, P., ET AL. Brit. J. Psychiat. 116: 615, 1970.

    Article  PubMed  CAS  Google Scholar 

  113. WEINSTEIN, M.R. GOLDFIELD, M.D. (Letter to editor) J.A.M.A. 214: 1325, 1970.

    Article  PubMed  CAS  Google Scholar 

  114. SZABO, K.T. Nature (London) 225: 73, 1970.

    Article  CAS  Google Scholar 

  115. SHIRKEY, H.C. Ann. Intern. Med. 73: 336, 1970.

    PubMed  CAS  Google Scholar 

  116. VACAFLOR, L., LEHMANN, H.E. BAN, T.A. J. Clin. Pharmacoz. 10: 387, 1970.

    CAS  Google Scholar 

  117. SCHOU, M. AMIDSON, A. Lancet 1: 1391, 1970.

    Article  PubMed  CAS  Google Scholar 

  118. WOODY, J.N., LONDON, W.L. WILBANK, G.D., JR. Pediatrics 47: 94, 1971.

    PubMed  CAS  Google Scholar 

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Shirkey, H.C. (1972). Human Experiences Related to Adverse Drug Reactions to the Fetus or Neonate from Some Maternally Administered Drugs. In: Klingerg, M.A., Abramovici, A., Chemke, J. (eds) Drugs and Fetal Development. Advances in Experimental Medicine and Biology, vol 27. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3219-0_3

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