Abstract
This chapter attempts to answer the following linked questions:
-
1
What is the simplest adequate description of the effects of the “minor tranquilizers” on “emotional behavior” (terms I shall define below)?
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2
What underlying psychological processes are altered by these drugs to produce these behavioral effects, and in what way are they altered?
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3
On what brain structures or systems do these drugs act to produce these behavioral effects?
Is the anti-anxiety effect of the benzodiazepines therefore a central anti-adre;nergic phenomenon? And if so, what is the role of brain norepinephrine in the chain of events which leads to psychoneurotic fear? —Zbinden and Randall (1967, p. 284)
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Gray, J.A. (1977). Drug Effects on Fear and Frustration: Possible Limbic Site of Action of Minor Tranquilizers. In: Iversen, L.L., Iversen, S.D., Snyder, S.H. (eds) Drugs, Neurotransmitters, and Behavior. Handbook of Psychopharmacology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3180-3_10
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