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Autoimmunity, Oncornaviruses, and Lymphomagenesis

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Contemporary Topics in Immunobiology

Part of the book series: Contemporary Topics in Immunobiology ((CTI,volume 6))

Abstract

C-type oncornaviruses have been associated with a variety of disease states in experimental animals (Hirsch and Black, 1974; Dixon et al., 1974; Levy, 1974; Todaro and Huebner, 1972). Much attention has been directed toward evaluating their role in lymphoproliferative disorders; recently, they have also been considered to play important roles in the induction of, or maintenance of, autoimmune diseases (Hirsch and Proffitt, 1975; Levy, 1974; Dixon et al., 1974). C-type viral genetic information may be acquired through horizontal infection either by experimental injection or by natural transmission of infectious virus; such genetic information may also be vertically transmitted through germ cells from parent to offspring, and may be in the form of integrated proviral DNA (Hirsch and Black, 1974; Todaro and Huebner, 1972; Temin, 1972).

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Authors and Affiliations

  1. Infectious Disease Unit Massachusetts General Hospital and Department of Medicine, Harvard Medical School, Boston, Massachusetts, 02114, USA

    Martin S. Hirsch, Max R. Proffitt & Paul H. Black

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  1. Martin S. Hirsch
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  2. Max R. Proffitt
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Editors and Affiliations

  1. Basic Research Program, NCI Frederick Cancer Research Center, Frederick, Maryland, 21701, USA

    Michael G. Hanna Jr.

  2. Department of Microbiology and Specialized Cancer Research Center The Milton S. Hershey Medical Center, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, 17033, USA

    Fred Rapp

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Hirsch, M.S., Proffitt, M.R., Black, P.H. (1977). Autoimmunity, Oncornaviruses, and Lymphomagenesis. In: Hanna, M.G., Rapp, F. (eds) Contemporary Topics in Immunobiology. Contemporary Topics in Immunobiology, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3051-6_7

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  • DOI: https://doi.org/10.1007/978-1-4684-3051-6_7

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