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Brain

  • Chapter
Lipid Metabolism in Mammals

Part of the book series: Monographs in Lipid Research ((MLR))

Abstract

The brain is an extremely complex organ with its many cell types, myelinated axons, complex anatomical structure, and the so-called blood-brain barrier. Lipids account for approximately 33% of the dry weight of the grey matter of adult human brain and 55% of the white matter dry weight (Bowen et al., 1974). The lipid composition and metabolism vary greatly with age and development; some compartments, such as the myelin lipids, have a slow turnover, while other compartments are very active. The brain contains two major cell types: the neurons, which are the functionally active cells, and the glial cells that are generally divided into two major types, the astrocytes, which appear to have a nutritive role, and the oligodendrocytes, which form the myelin. All these factors combine, making it difficult to obtain pure subcellular fractions and to interpret metabolic findings in studies of lipid metabolism in the brain.

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    Robert L. Wykle

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    Fred Snyder

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Wykle, R.L. (1977). Brain. In: Snyder, F. (eds) Lipid Metabolism in Mammals. Monographs in Lipid Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2832-2_10

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