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Reproduction of Myxoviruses

  • Chapter
Comprehensive Virology

Abstract

The myxovirus group consists of the influenza viruses of man and animals. The designation was originally suggested (Andrewes et al., 1955) for a group of viruses which exhibited affinity for certain mucoid substances, and included mumps and Newcastle disease viruses (NDV) in addition to influenza viruses. It was recognized subsequently that the former two viruses should be separated into a distinct group because of numerous differences in structure and replication between them and the influenza viruses (Waterson, 1962), and the term paramyxovirus has been adopted for the group which includes these agents. Thus, the myxovirus group (sometimes referred to as orthomyxoviruses; Melnick, 1973) as presently constituted contains only the influenza viruses. As described in sect. 2, among the polypeptides of the influenza virion are two distinct surface polypeptides with hemagglutinin and neuraminidase activities and an internal ribonucleoprotein (RNP). The antigenicity of these polypeptides has provided a basis for the classification of influenza viruses into types, subtypes, and strains. Table 1 indicates the system of classification and lists some of the strains in common use.

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Authors and Affiliations

  1. The Rockefeller University, New York, New York, 10021, USA

    Richard W. Compans & Purnell W. Choppin

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  1. Richard W. Compans
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Editors and Affiliations

  1. Department of Molecular Biology and Virus Laboratory, University of California, Berkeley, California, USA

    Heinz Fraenkel-Conrat

  2. Department of Microbiology, University of Virginia, Charlottesville, Virginia, USA

    Robert R. Wagner

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© 1975 Plenum Press, New York

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Compans, R.W., Choppin, P.W. (1975). Reproduction of Myxoviruses. In: Fraenkel-Conrat, H., Wagner, R.R. (eds) Comprehensive Virology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2706-6_3

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  • DOI: https://doi.org/10.1007/978-1-4684-2706-6_3

  • Publisher Name: Springer, Boston, MA

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