Abstract
The demonstration of the prophylactic effect of lithium has been more difficult than the demonstration of its therapeutic effect. A convincing demonstration of the efficacy of this treatment was particularly important, because lithium has a relatively narrow therapeutic range. Prophylactic lithium treatment has been the subject of much debate, and a number of experimental designs were used to demonstrate its value. These studies have not only shed light on the clinical and pharmacological properties of the lithium ion; they have also provided new knowledge about the recurrent endogenous affective disorders.
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Schou, M. (1973). Prophylactic Lithium Maintenance Treatment in Recurrent Endogenous Affective Disorders. In: Gershon, S., Shopsin, B. (eds) Lithium. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2022-7_15
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DOI: https://doi.org/10.1007/978-1-4684-2022-7_15
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