Abstract
The vertebrate retina contains a variety of neuronal con-nections which depend on chemical communication. Both excitatory and inhibitory synapses are present: A substantial list of putative transmitter agents has been expanded in recent years by techniques which have localized several peptides to the retina (Brecha and Karten, 1979; Stell et al., 1980). The physiologist who attempts to define transmitter action in the retina does not suffer from an abbreviated list of agents which may subserve secretory transmission. We have studied the action of several transmitter candidates and their antagonists using intracellular recording techniques in the perfused retina-eyecup preparation of the mudpuppy (Necturus maculosus). We have also studied the effects of several peptides which have been localized to the mudpuppy retina through immunohistochemical techniques of Brecha and Karten. Our findings support the concept that excitatory and inhibitory amino acids, as well as some peptides may be involved in synaptic transmission.
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Miller, R.F., Slaughter, M.M., Dick, E. (1982). Excitatory, Inhibitory and Peptidergic Pathways in the Mudpuppy Retina. In: Bradford, H.F. (eds) Neurotransmitter Interaction and Compartmentation. NATO Advanced Study Institutes Series, vol 48. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1140-9_47
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DOI: https://doi.org/10.1007/978-1-4684-1140-9_47
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