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An Overview of Metal Carcinogenesis

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Inorganic and Nutritional Aspects of Cancer

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 91))

Abstract

Metal or inorganic carcinogenesis has come of age. Originally considered an obscure phase of the cancer problem, it was neglected for many years. Reviews on the topic carcinogenesis either failed to mention metals as causative agents or simply included a few ions as examples of an unusual class. Another area of neglect has been the association of occupational exposure to dusts, fumes, and even vapors of inorganic chemicals with an increase in various types of cancer among certain industrial workers. This phenomenon was first noted in the 1880s but did not result in laboratory investigations. Virchow, one of the early pioneering pathologists, suggested that this cancer rise could be linked to a “chronic irritation theory”, but this explanation stirred no imaginative research.

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Author information

Authors and Affiliations

  1. Institute of Chemical Biology, University of San Francisco, San Francisco, California, USA

    Arthur Furst

  2. Department of Pharmacology, Stanford University School of Medicine, Stanford, California, USA

    Arthur Furst

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  1. Arthur Furst
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Editor information

Editors and Affiliations

  1. University of California at San Diego, La Jolla, California, USA

    G. N. Schrauzer

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© 1978 Plenum Press, New York

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Furst, A. (1978). An Overview of Metal Carcinogenesis. In: Schrauzer, G.N. (eds) Inorganic and Nutritional Aspects of Cancer. Advances in Experimental Medicine and Biology, vol 91. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0796-9_1

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  • DOI: https://doi.org/10.1007/978-1-4684-0796-9_1

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-0798-3

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