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Scale-Up of Protein Purification by Liquid-Liquid Extraction

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Enzyme Engineering

Abstract

New demands and renewed interests in large scale protein isolation processes have arisen from recent advances in enzyme technology, e.g. enzymic transformation with cofactor regeneration (1) or new developments in the production of biologically active proteins, such as interferon or proteo-hormons by recombinant-DNA technology (2).

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References

  1. Wichmann, R., Wandrey, C., Bückmann, A. F. & Kula, M.-R Biotechnol. Bioeng., in press.

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  2. Weissmann, C. et al., this volume.

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  3. Kula, M.-R., Kroner, K. H., Hustedt, H., Granda, S. & STACH, W., German Patent 26 39 129, US Patent 4,144,130.

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  9. Kula, M.-R., Kroner, K. H., Hustedt, H. & Schutte, H. Ann. NY Aoad. Sci. 369: 341 (1981)

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Author information

Authors and Affiliations

  1. Gesellschaft für Biotechnologische Forschung mbH, Braunschweig-Stockheim, Federal Republic of Germany

    M.-R. Kula, K. H. Kroner, H. Hustedt & H. Schutte

Authors
  1. M.-R. Kula
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  2. K. H. Kroner
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  3. H. Hustedt
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  4. H. Schutte
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Editor information

Editors and Affiliations

  1. Research Laboratory of Applied Biochemistry, Tanabe Seiyaku Company, Osaka, Japan

    Ichiro Chibata

  2. Department of Industrial Chemistry, Faculty of Engineering, Kyoto University, Kyoto, Japan

    Saburo Fukui

  3. Department of Pharmacology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

    Lemuel B. Wingard Jr.

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© 1982 Plenum Press, New York

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Kula, MR., Kroner, K.H., Hustedt, H., Schutte, H. (1982). Scale-Up of Protein Purification by Liquid-Liquid Extraction. In: Chibata, I., Fukui, S., Wingard, L.B. (eds) Enzyme Engineering. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9290-7_6

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  • DOI: https://doi.org/10.1007/978-1-4615-9290-7_6

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9292-1

  • Online ISBN: 978-1-4615-9290-7

  • eBook Packages: Springer Book Archive

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