Abstract
The classical patient with gout is usually an older male, and gout is rare in premenopausal females1. Until recently, renal failure was common in gout2, but is now rare3. Renal involvement however, as judged by low urine pH and proteinuria, remains common1,3,4, although concentrating ability and GFR are not usually different from age-matched controls3. Conversely, gout is rarely diagnosed in renal failure from other causes, despite mild hyperuricaemia as part of the general retention of nitrogenous waste4,5. If all patients entering terminal renal failure and offered dialysis or transplantation are examined, less than 1% have gout recorded as the cause (Table 1).
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Simmonds, H.A., Cameron, J.S., Potter, C.F., Warren, D., Gibson, T., Farebrother, D. (1980). Renal Failure in Young Subjects with Familial Gout. In: Rapado, A., Watts, R.W.E., De Bruyn, C.H.M.M. (eds) Purine Metabolism in Man-III. Advances in Experimental Medicine and Biology, vol 122A. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9140-5_3
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