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Proposed Reclassification of Shock States with Special Reference to Distributive Defects

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The Fundamental Mechanisms of Shock

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 23))

Abstract

Some years ago, for lack of better knowledge, most of us were tempted to classify shock on an etiologic basis. We referred to: (a) shock due to blood loss (hypovolemic shock); (b) cardiogenic shock (pump failure); (c) bacterial shock (bacteremia, endotoxin); (d) acute hypersensitivity reactions (anaphylactic shock); (e) neurogenic shock (barbiturate and narcotic overdose, transection of the spinal cord; (f) shock associated with obstruction to blood flow, e. g., pulmonary embolization; and (g) endocrine forms of shock (myxedema, pheochromocytoma, adrenocortical insufficiency, insulin excess).

This study was supported by USPHS Research Grants HE-00570 from the National Heart and Lung Institute, GM-16462 from the National Institute of General Medical Sciences, and HS-00238 from the National Center for Health Services and Development, HSMHA.

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References

  1. Shubin, H., and M.H. Weil. The mechanism of shock following suicidal doses of barbiturates, narcotics, and tranquilizer drugs, with observations on the effects of treatment. Am. J. Med. 38: 857, 1965.

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  2. Udhoji, V.N,, and M.H. Weil. Hemodynamic and metabolic studies on shock associated with bacteremia: Observations on 16 patients. Ann. Intern. Med. 62: 966–978, 1965.

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  3. Weil, M.H., L.D. MacLean, W.W. Spink, and M.B. Visscher. Studies on the circulatory changes in the dog produced by endotoxin from gram-negative microorganisms. J. Clin. Invest. 35: 1194, 1956.

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  4. Weil, M.H., and H. Shubin. Diagnosis and Treatment of Shook. Baltimore: Williams amp; Wilkins, 1967, p. 10.

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© 1972 Plenum Press, New York

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Weil, M.H., Shubin, H. (1972). Proposed Reclassification of Shock States with Special Reference to Distributive Defects. In: Hinshaw, L.B., Cox, B.G. (eds) The Fundamental Mechanisms of Shock. Advances in Experimental Medicine and Biology, vol 23. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9014-9_3

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  • DOI: https://doi.org/10.1007/978-1-4615-9014-9_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9016-3

  • Online ISBN: 978-1-4615-9014-9

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