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Microbial Ecology of the Human Skin

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Advances in Microbial Ecology

Part of the book series: Advances in Microbial Ecology ((AMIE,volume 2))

Abstract

From a microbial viewpoint the human skin must constitute a poor environment on which to live and reproduce. It is subject to periodic flooding followed by comparatively long periods of drought, it may be exposed to UV light in sunshine, its nutrient exudates may also contain toxic substances, and there may be “pollution” in the form of specific antibacterial compounds, perfumes, or heavy metals derived from other environmental sources. Finally, the physical environment is in a continual state of erosion. Yet almost the whole skin surface is colonized by microorganisms, sometimes in large numbers.

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References

  • Adlam. C., 1973a, Corynebacterium parvum and its effects on the lymphoreticular system, Lab-Lor (Wellcome) 5:273.

    Google Scholar 

  • Adlam. C., 1973b, Studies on histamine sensitization in mice by Corynebacterium parvum, J. Med. Microbiol. 6:527.

    CAS  PubMed  Google Scholar 

  • Aly, R., Maibach, H. I., Shinefield, H. R., and Mandel, A. D., 1974a, Staphylococcus aureus carriage in twins, Am. J. Dis. Child. 127:486.

    CAS  PubMed  Google Scholar 

  • Aly, R., Maibach, H. I., Shinefield, H. R., Mandel, A., and Strauss, W. G., 1974b, Bacterial interference among strains of Staphylococcus aureus in man, J. Infect. Dis. 129:720.

    CAS  PubMed  Google Scholar 

  • Aly, R., Shinefield, H. I., Strauss, W. G., and Maibach, H. I., 1977, Bacterial adherence to nasal mucosal cells, Infect. Immun. 17:546.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Azuma, I., Sugimura, K., Taniyama, T., Aladin, A. A., and Yamamura, Y., 1975, Chemical and immunological studies on the cell walls of Propionibacterium acnes strain C7 and Corynebacterium parvum ATCC 11829, Jpn. J. Microbiol. 19:265.

    CAS  PubMed  Google Scholar 

  • Baird-Parker, A. C., 1963, A classification of micrococci and staphylococci based on physiological and biochemical tests, J. Gen. Microbiol. 30:409.

    CAS  PubMed  Google Scholar 

  • Baird-Parker, A. C., 1965, The classification of staphylococci and micrococci from world-wide sources, J. Gen. Microbiol. 38:363.

    CAS  PubMed  Google Scholar 

  • Baird-Parker, A. C., 1974a, The basis for the present classification of staphylococci and micrococci, Ann. N. Y. Acad. Sci. 236:7.

    CAS  PubMed  Google Scholar 

  • Baird-Parker, A. C., 1974b, Family Micrococcaceae, in: Bergey’s Manual of Determinative Bacteriology (R. E. Buchanan and N. E. Gibbons, eds.), p. 478, Williams and Wilkins, Baltimore.

    Google Scholar 

  • Balfour, H. H., and Minken, S. L., 1971, Liver abscess due to Corynebacterium acnes. Diphtheroid as pathogen, Clin. Pediatr. 10:55.

    Google Scholar 

  • Bartholomew, L. E., and Nelson, F. R., 1972, Corynebacterium acnes in rheumatoid arthritis. Isolation and antibody studies, Ann. Rheum. Dis. 31:22.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Beeler, B. A., Crowder, J. G., Smith, J. W., and White, A., 1976, Propionibacterium acnes: pathogen in central nervous system shunt infection. Report of three cases including immune complex glomerulonephritis, Am. J. Med. 61:935.

    CAS  PubMed  Google Scholar 

  • Behrendt, H., and Green, M., 1971, Patterns of Skin pH from Birth through Adolescence, Charles C. Thomas, Springfield, Ill.

    Google Scholar 

  • Berd, D., 1973, Laboratory identification of clinically important aerobic actinomycetes, Appl. Microbiol. 25:665.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Bibel, D. J., and LeBrun, J. R., 1975, Effect of experimental dermatophyte infection on cutaneous flora, J. Invest. Dermatol. 64:119.

    CAS  PubMed  Google Scholar 

  • Bibel, D. J., and Lovell, D. J., 1976, Skin flora maps: A tool in the study of cutaneous ecology, J. Invest. Dermatol. 66:265.

    Google Scholar 

  • Bibel, D. J., Aly, R., and Maibach, H. I., 1976a, Nomenclature of cutaneous Micrococcaceae: on the brink of chaos, Int. J. Dermatol. 15:670.

    CAS  PubMed  Google Scholar 

  • Bibel, J. D., Lovell, D. J., and Smiljanic, R. J., 1976b, Effect of occlusion upon population dynamics of skin bacteria, Br. J. Dermatol. 95:607.

    CAS  PubMed  Google Scholar 

  • Bollgren, J., and Winberg, J., 1976, The periurethral aerobic flora in healthy girls and boys, Acta Pediatr. Scand. 65:74.

    CAS  Google Scholar 

  • Boone, C. J., and Pine, L., 1968, Rapid method for the characterization of actinomycetes by cell wall composition, Appl. Microbiol. 16:279.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Brodersen, M., and Wirth, M., 1976, Detection of HBS Ag and HBsAb in sweat, Acta Hepato-gastroenterol. 23:194.

    CAS  Google Scholar 

  • Brooks, K., and Sodeman, T., 1974, Clinical studies on a transformation test for identification of Acinetobacter (Mima and Herellea), Appl. Microbiol. 27:1023.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Cabau, N., Levy, F.-M., and Muller, O., 1974, Les immunoglobulines sudorales chez l’enfant, Path. Biol. 22:883.

    CAS  Google Scholar 

  • Chin, P., and Davis, D. G., 1976, The skin flora of the hémiplégie hand, J. Hyg. (Camb.) 77:93.

    CAS  Google Scholar 

  • Christian, J. H. B., and Waltho, J. A., 1962, The water relations of staphylococci and micrococci, J. Appl. Bacteriol. 25:369.

    Google Scholar 

  • Cowan, S. T., 1968, A Dictionary of Microbial Taxonomic Usage, Oliver and Boyd, Edinburgh.

    Google Scholar 

  • Cummins, C. S., 1962, Chemical composition and antigenic structure of cell walls of Corynebacterium, Mycobacterium, Nocardia, Actinomyces and Arthrobacter, J. Gen. Microbiol. 28:35.

    CAS  PubMed  Google Scholar 

  • Cummins, C. S., 1970, Cell wall composition in the classification of gram positive anaerobes, Int. J. System. Bacteriol. 20:413.

    Google Scholar 

  • Cummins, C. S., and Harris, H., 1956, The chemical composition of the cell wall in some gram-positive bacteria and its possible value as a taxonomic character, J. Gen. Microbiol. 14:583.

    CAS  PubMed  Google Scholar 

  • Cummins, C. S., and Harris, H., 1958, Studies on the cell wall composition and taxonomy of actinomycetales and related groups, J. Gen. Microbiol. 18:173.

    CAS  PubMed  Google Scholar 

  • Cummins, C. S., and Johnson, J. L., 1973, Corynebacterium parvum: a synonym for Propionibacterium acnes? J. Gen. Microbiol. 80:433.

    Google Scholar 

  • Dahl, M. G. C., and McGibbon, D. H., 1976, Complement in inflammatory acne vulgaris, Br. Med. J. 4:1383.

    Google Scholar 

  • Davis, G. H. G., and Hoyling, B., 1974, Observations on anaerobic glucose utilization tests in Staphylococcus Micrococcus, Int. J. System. Bacteriol. 24:1.

    Google Scholar 

  • Dawes, J., and McBride, W. H., 1975, Analysis of anaerobic coryneform cell wall antigens by radioimmunoassay, Immunochemistry 12:855.

    CAS  PubMed  Google Scholar 

  • Duborgel, S., 1974, Etude de corynebacteries anaerobes isolées à partir de 9000 hemocultures, Ann. Biol. Clin. 32:487.

    CAS  Google Scholar 

  • Duncan, W. C., McBride, M. E., and Knox, J. M., 1969, Bacterial flora: the role of environmental factors, J. Invest. Dermatol. 52:479.

    CAS  PubMed  Google Scholar 

  • Elias, P. M., Fritsch, P., and Mittermayer, H., 1976, Staphylococcal toxic epidermal necrolysis: species and tissue susceptibility and resistance, J. Invest. Dermatol. 66:80.

    CAS  PubMed  Google Scholar 

  • Elias, P. M., Fritsch, P., and Epstein, E. H., 1977, Staphylococcal scalded skin syndrome. Clinical features, pathogenesis, and recent microbiological and biochemical developments, Arch. Dermatol. 113:207.

    CAS  PubMed  Google Scholar 

  • Emmett, M., and Kloos, W. E., 1975, Amino acid requirements of staphylococci isolated from human skin, Can. J. Microbiol. 21:729.

    CAS  PubMed  Google Scholar 

  • Evans, C. A., 1975, Persistent individual differences in the bacterial flora of the skin of the forehead. Numbers of Propionibacteria, J. Invest. Dermatol. 64:42.

    CAS  PubMed  Google Scholar 

  • Evans, J. B., and Kloos, W. E., 1972, Use of shake cultures in a semisolid thioglycolate medium for differentiating Staphylococci from Micrococci, Appl. Microbiol. 23:326.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Evans, N. M., 1968, The classification of aerobic diphtheroids from human skin, Br. J. Dermatol. 80:81.

    CAS  PubMed  Google Scholar 

  • Farrior, J. W., and Kloos, W. E., 1976, Sulfur amino acid auxotrophy in Micrococcus species isolated from human skin, Can. J. Microbiol. 22:1680.

    CAS  PubMed  Google Scholar 

  • Ford, E. B., 1975, Ecological Genetics, Chapman and Hall, London.

    Google Scholar 

  • Förström, L., Goldyne, M. E., and Winkelmann, R. K., 1975, IgE in human eccrine sweat, J. Invest. Dermatol. 64:156.

    PubMed  Google Scholar 

  • Fuller, R., 1975, Nature of the determinant responsible for the adhesion of lactobacilli to chicken crop epithelial cells, J. Gen. Microbiol. 87:245.

    CAS  PubMed  Google Scholar 

  • Galinski, J., 1975, Staphylococcus aureus strains of phage group II and their possible relation to animal staphylococci, Zentralbl. Bakteriol. Hyg. Abt. I, Orig. A 233:288.

    CAS  Google Scholar 

  • Gloor, M., Kionke, M., and Friederich, H. C., 1975a, Biochemical and physiological parameters on the skin surface of healthy test persons, Arch. Dermatol. Res. 252:317.

    CAS  Google Scholar 

  • Gloor, M., Kumpel, D., and Friederich, H. C., 1975b, Predisposing factors on the surface of the skin in persons with pityriasis versicolor, Arch. Dermatol. Res. 254:281.

    CAS  PubMed  Google Scholar 

  • Gloor, M., Marckardt, V., and Friederich, H. C., 1975c, Biochemical and physiological particularities on the skin surface of diabetics, Arch. Dermatol. Res. 253:185.

    CAS  PubMed  Google Scholar 

  • Gloor, M., Weigel, H. J., and Friederich, H. C., 1975d, Predisposing factors of the skin surface in persons with impetigo contagiosa, Arch. Dermatol. Res. 254:95.

    CAS  PubMed  Google Scholar 

  • Gloor, M., Baumann, C., and Friederich, H. C., 1976a, Biochemical and physiological parameters on the healthy skin surface of patients with common warts, Dermatologica 152:152.

    CAS  PubMed  Google Scholar 

  • Gloor, M., Geilhof, A., Ronneberger, G., and Friederich, H. C., 1976b, Biochemical and physiological parameters on the healthy skin surface of persons with candidal intertrigo and of persons with tinea cruris, Arch. Dermatol. Res. 257:203.

    CAS  PubMed  Google Scholar 

  • Greene, R. S., Downing, D. T., Pochi, P. E., and Strauss, J. S., 1970, Anatomical variation in the amount and composition of human skin surface lipids,J. Invest. Dermatol. 54:240.

    CAS  PubMed  Google Scholar 

  • Haavik, H., 1976, Possible functions of peptide antibiotics during growth of producer organisms: bacitracin and metal (II) ion transport, Acta Pathol. Microbiol. Scand. B. 84:117.

    CAS  PubMed  Google Scholar 

  • Halvorson, H., 1972, Utilization of single L amino acids as role source of carbon and nitrogen by bacteria, Can. J. Microbiol. 18:1647.

    CAS  PubMed  Google Scholar 

  • Heckels, J. E., Blackett, B., Everson, J. S., and Ward, M. E., 1976, The influence of surface charge on the attachment of Neisseria gonorrhoeae to human cells, J. Gen. Microbiol. 96:359.

    CAS  PubMed  Google Scholar 

  • Henning, D. R., Griffin, T. B., and Maibach, H. I., 1972, Studies on changes in skin surface bacteria in induced miliaria and associated hypohidrosis, Acta Dermatovener. (Stockh.) 52:371.

    CAS  Google Scholar 

  • Herrman, W. P., and Habbig, J., 1976, Immunological demonstration of multiple esterases in human eccrine sweat, Br. J. Dermatol. 95:67.

    Google Scholar 

  • Hoeksma, A., and Winkler, K. C., 1963, The normal flora of the nose in twins, Acta Leidensia 32:124.

    Google Scholar 

  • Holland, K. T., Roberts, C. D., Cunliffe, W. J., and Williams, M., 1974, A technique for sampling microorganisms from the pilosebaceous ducts, J. Appl. Bacteriol. 37:289.

    CAS  PubMed  Google Scholar 

  • Holt, R. J., 1969, Studies on the microflora of the normal human skin, Ph.D. Thesis, Council for National Academic Awards, London.

    Google Scholar 

  • Jarvis, B., Reynolds, A. J., Rhodes, A. C., and Armstrong, M., 1974, A survey of microbiological contamination in cosmetics and toiletries m the UK (1971), J. Soc. Cos. Chem. 25:563.

    Google Scholar 

  • Jenkinson, D. McE., Mabon, R. M., and Manson, W., 1974, The effect of temperature and humidity on the losses of nitrogenous protein from the skin of Ayrshire cattle, Res. Vet. Sci. 17:75.

    CAS  PubMed  Google Scholar 

  • Johnson, J. L., and Cummins, C. S., 1972, Cell wall composition and deoxyribonucleic acid similarities among the anaerobic coryneforms: classicalpropionibacteria, and strains of Arachnia propionica, J. Bacteriol. 109:1037.

    Google Scholar 

  • Jong, E. C., Ko, H. L., and Pulverer, G., 1975, Studies on bacteriophages of Propionibacterium acnes, Med. Microbiol. Immunol. 161:263.

    CAS  PubMed  Google Scholar 

  • Juni, E., 1972, Interspecies transformation of Acinetobacter: genetic evidence for a ubiquitous genus, J. Bacteriol. 112:917.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Kalakoutskii, L. V., and Agre, N. S., 1976, Comparative aspects of development and differentiation in Actinomycetes, Bacteriol. Rev. 40:469.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Kaplan, E. L., and Wannamaker, L. W., 1976, Suppression of the antistreptolysin O response by cholesterol and by lipid extracts of rabbit skin, J. Exp. Med. 144:754.

    CAS  PubMed  Google Scholar 

  • Kasprowicz, A., Heczko, P. B., and Kucharczyk, J., 1974, Proba Klasyfikacji Maczogowcow Skórnych, Medycyna Doswiadczalora I Mikrobiollogia 26:267.

    CAS  Google Scholar 

  • Keddie, R. M., and Cure, G. L., 1977, The cell wali composition and distribution of free mycolic acids in named strains of coryneform bacteria and in isolates from natural sources, J. Appl. Bacteriol. 42:229.

    CAS  PubMed  Google Scholar 

  • Kellum, R. E., 1976, Acne vulgaris. Studies in pathogenesis. Suppression of non-specific esterases, Cutis 17:510.

    CAS  PubMed  Google Scholar 

  • Kellum, R. E., and Strangfeld, K., 1972, Acne vulgaris. Studies in pathogenesis. Fatty acids of human surface triglycerides from patients with and without acne, J. Invest. Dermatol. 58:315.

    CAS  PubMed  Google Scholar 

  • Kligman, A. M., 1965, The bacteriology of normal skin, in: Skin Bacteria and Their Role in Infection (H. I. Maibach and G. Hildick-Smith, eds.), pp. 13–31, McGraw-Hill, New York.

    Google Scholar 

  • Kligman, A. M., McGinley, K. J., and Leyden, J. J., 1976, The nature of dandruff, J. Soc. Cos. Chem. 27:111.

    Google Scholar 

  • Kloos, W. E., and Musselwhite, M.S., 1975, Distribution and persistance of Staphylococcus and Micrococcus species and other aerobic bacteria on human skin, Appl. Microbiol. 30:381.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Kloos, W. E., and Schleifer, K. H., 1975a, Simplified scheme for routine identification of human Staphylococcus species, J. Clin. Microbiol. 1:82.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Kloos, W. E., and Schleifer, K. H., 1975b, Isolation and characterization of Staphylococci from human skin. II. Descriptions of four new species: Staphylococcus warneri, Staphylococcus capitis, Staphylococcus hominis, and Staphylococcus simulans, Int. J. System. Bacteriol. 25:62.

    CAS  Google Scholar 

  • Kloos, W. E., Tornabene, T. G., and Schleifer, K. H., 1974, Isolation and characterization of micrococci from human skin, including two new species: Micrococcus lylae and Micrococcus kristinae, Int. J. System. Bacteriol. 24:97.

    Google Scholar 

  • Kloos, W. E., Schleifer, K. H., and Noble, W. C., 1976a, Estimation of character parameters in coagulase negative Staphylococcus species, in: Staphylococci and Staphylococcal Disease, pp. 23–41, Zentralbl. Bakterio! Parasitenk. I. k. Abt. 1, Supplementum 5.

    Google Scholar 

  • Kloos, W. E., Schleifer, K. H., and Smith, R. F., 1976b, Characterization of Staphylococcus sciuri sp. nov. and its subspecies, Int. J. System. Bacteriol. 26:22.

    Google Scholar 

  • Kocur, M., and Boháček, J., 1974, DNA base composition and the classification of non-pigmented micrococci, Microbios 10A:31.

    CAS  PubMed  Google Scholar 

  • Kocur, M., and Schleifer, K. H., 1975, Taxonomic status of Micrococcus agilis, Ali Cohen 1889, Int. J. System. Bacteriol. 25:294.

    CAS  Google Scholar 

  • Knight, A. G., 1973, Culture of dermatophytes upon stratum corneum, J. Invest. Dermatol. 59:427.

    Google Scholar 

  • Knight, A. G., 1976, The effect of temperature and humidity on the growth of Trichophyton mentagrophytes spores on human stratum corneum in vitro, Clin. Exp. Dermatol. 1:159.

    CAS  Google Scholar 

  • Kryński, S., Becla, E., Sarnet, A., Nowicki, B., and Wielgosz, A., 1975, Usefulness of phage typing for identification of Staphylococcus epidermidis and Micrococcus strains, Arch. Immunol. Ther. Exp. 23:645.

    Google Scholar 

  • Lacey, R. W., 1971, High frequency transfer to neomycin resistance between naturally occurring strains of Staphylococcus aureus, J. Med. Microbiol. 4:73.

    CAS  PubMed  Google Scholar 

  • Lacey, R. W., 1975, Antibiotic resistance plasmids of Staphylococcus aureus and their clinical importance, Bacteriol. Rev. 39:1.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Lantrop, H., 1974, Genus Acinetobacter, in: Bergey’s Manual of Determinative Bacteriology (R. E. Buchanan and N. E. Gibbons, eds.), p. 436, Williams and Wilkins, Baltimore.

    Google Scholar 

  • Lawrence, J. C., and Lilly, H. A., 1972, A quantitative method for investigating the bacteriology of skin: its application to burns, Br. J. Exp. Pathol. 53:550.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Lechevalier, M. P., and Lechevalier, H., 1970, Chemical composition as a criterion in the classification of aerobic actinomycetes, Int. J. System. Bacteriol. 20:435.

    CAS  Google Scholar 

  • Lee, L. D., and Baden, H. P., 1975, Chemistry and composition of the keratins, Int. J. Dermatol. 14:161.

    CAS  PubMed  Google Scholar 

  • Leyden, J. J., 1976, Antibiotic resistant acne, Cutis 17:593.

    CAS  PubMed  Google Scholar 

  • Leyden, J. J., and Kligman, A. M., 1976, Acne vulgaris: New concepts in pathogenesis and treatment, Drugs 12:292.

    CAS  PubMed  Google Scholar 

  • Leyden, J. J., Marples, R. R., Mills, O. H., and Kligman, A. M., 1973, Gram negative folliculitis—A complication of antibiotic therapy in acne vulgaris, Br. J. Dermatol. 88:533.

    CAS  PubMed  Google Scholar 

  • Leyden, J. J., McGinley, K. J., Mills, O. H., and Kligman, A. M., 1975, Propionibacterium levels in patients with and without acne vulgaris, J. Invest. Dermatol. 65:382.

    CAS  PubMed  Google Scholar 

  • Lilly, D. M., and Stillwell, R. H., 1965, Probiotics: Growth promoting factors produced by microorganisms, Science 147:747.

    CAS  PubMed  Google Scholar 

  • Loebl, E. C., Marvin, J. A., Heck, E. L., Curreri, P. W., and Baxter, C. R., 1974, The use of quantitative biopsy cultures in bactériologie monitoring of burn patients, J. Surg. Res. 16:1.

    CAS  PubMed  Google Scholar 

  • Lodder, J., 1970, The Yeasts, 2nd ed., North-Holland, Amsterdam.

    Google Scholar 

  • Mardh, P. A., and Westrom, L., 1976, Adherence of bacteria to vaginal epithelial cells, Infect. Immun. 13:661.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Marks, R., and Dawber, R. P. R., 1972, In situ microbiology of the stratum corneum, Arch. Dermatol. 105:216.

    CAS  PubMed  Google Scholar 

  • Marples, M. J., 1965, The Ecology of the Human Skin, Charles C. Thomas, Springfield, Ill.

    Google Scholar 

  • Marples, R. R., 1969, Diphtheroids of normal human skin, Br. J. Dermatol., Suppl. 1, 81:47.

    PubMed  Google Scholar 

  • Marples, R. R., and Kligman, A. M., 1971, Ecological effects of oral antibiotics on the microflora of human skin, Arch. Dermatol. 103:148.

    CAS  PubMed  Google Scholar 

  • Marples, R. R., Downing, D. T., and Kligman, A. M., 1971, Control of fatty acids in human skin surface lipids by Corynebacterium acnes, J. Invest. Dermatol. 56:127.

    CAS  PubMed  Google Scholar 

  • Marsh, P. D., and Selwyn, S., 1977a, Studies on antagonism between human skin bacteria, J. Med. Microbiol. 10:161.

    CAS  PubMed  Google Scholar 

  • Marsh, P. D., and Selwyn, S., 1977b, Continuous culture studies of interactions among skin commensal bacteria, J. Med. Microbiol. 10:261.

    CAS  PubMed  Google Scholar 

  • Massey, A., Mowbray, J. F., and Noble, W. C., 1978, Complement activation by Corynebacterium acnes, Br. J. Dermatol., in press.

    Google Scholar 

  • Matta, M., 1974, Carriage of Corynebacterium acnes in school children in relation to age and race, Br. J. Dermatol. 91:557.

    Google Scholar 

  • McAllister, T. A., Givan, J., Black, A., Turner, M. J., Kerr, M. M., and Hutchison, J. H., 1974, The natural history of bacterial colonization of the newborn in a maternity hospital, Scot. Med. J. 19:119.

    CAS  PubMed  Google Scholar 

  • McBride, M. E., Duncan, W. C., Bodey, G. P., and McBride, C. M., 1976, Microbial skin flora of selected cancer patients and hospital personnel, J. Clin. Microbiol. 3:14.

    CAS  PubMed Central  PubMed  Google Scholar 

  • McGinley, K. J., Leyden, J. J., Marples, R. R., and Kligman, A. M., 1975, Quantitative microbiology of the scalp in non-dandruff, dandruff and seborrhoeic dermatitis, J. Invest. Dermatol. 64:401.

    CAS  PubMed  Google Scholar 

  • McLaren, A. D. and Skujins, J., 1968, The physical environment of organisms in soil, in: The Ecology of Soil Bacteria, pp. 3–24, Liverpool University Press, Liverpool.

    Google Scholar 

  • Milyani, R. M. M., 1976, Studies on interactions of human skin microorganisms on solid surface, Ph.D. Thesis, University of London.

    Google Scholar 

  • Milyani, R. M. M., and Selwyn, S., 1978, Quantitative studies on competitive activities of skin bacteria growing on solid media, J. Med. Microbiol., in press.

    Google Scholar 

  • Montes, L. F., and Wilborn, W. H., 1969, Location of bacterial skin flora, Br. J. Dermatol. Suppl. 1 81:23.

    PubMed  Google Scholar 

  • Moore, W. E. C., and Holdeman, L. V., 1974, Family Propionibacteriaceae, in: Bergey’s Manual of Determinative Bacteriology (R. E. Buchanan and N. E. Gibbons, eds.), p. 633, Williams and Wilkins, Baltimore.

    Google Scholar 

  • Morello, A. M., and Downing, D. T., 1976, Trans-unsaturated fatty acids in human skin surface lipids, J. Invest. Dermatol. 67:270.

    CAS  PubMed  Google Scholar 

  • Mukasa, H., and Slade, H. D., 1974, Mechanism of adherence of Streptococcus mutans to smooth surfaces, Infect. Immun. 9:419.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Murphy, C. T., 1975, Nutrient materials and the growth of bacteria on human skin, Trans. St. John’s Hosp. Dermatol. Soc. 61:51.

    CAS  Google Scholar 

  • Mustakallio, K. K., Salo, O. P., Kiistala, R., and Kiistala, U., 1967, Counting the number of aerobic bacteria in full thickness human epidermis separated by suction, Acta Pathol. Microbiol. Scand. 69:477.

    Google Scholar 

  • Neill, J. M., Gaspari, E. L., Mosley, R. A., and Sugg, J. Y., 1931, Loss of immune substances from the body. III. Diphtheria antitoxin in human sweat, J. Immunol. 21:101.

    CAS  Google Scholar 

  • Noble, W. C., 1974, Carriage of Staphylococcus aureus and beta haemolytic streptococci in relation to race, Acta Dermatovener (Stockh.) 54:403.

    CAS  Google Scholar 

  • Noble, W. C., 1975, Skin as a microhabitat, Postgrad. Med. J. 51:151.

    PubMed Central  Google Scholar 

  • Noble, W. C., 1976, Dispersal of skin microorganisms, Br. J. Dermatol. 93:477.

    Google Scholar 

  • Noble, W. C., 1977a, Dispersal of organisms from human skin, Cosmetics Toiletries 92:38.

    Google Scholar 

  • Noble, W. C., 1977b, Variation in the prevalence of antibiotic resistance of Staphylococcus aureus from human skin and nares, J. Gen. Microbiol. 98:125.

    CAS  PubMed  Google Scholar 

  • Noble, W. C., and Somerville, D. A., 1974, Microbiology of Human Skin, Saunders, London.

    Google Scholar 

  • Noble, W. C., Valkenburg, H. A., and Wolters, C. H. L., 1967, Carriage of Staphylococcus aureus in random samples of a normal population, J. Hyg. (Camb.) 65:567.

    CAS  Google Scholar 

  • Notermans, S., and Kampelmacher, E. H., 1975, Further studies on the attachment of bacteria to skin, Br. Poultry Sci. 16:487.

    CAS  Google Scholar 

  • Page, C. O., and Remington, J. S., 1967, Immunologic studies in normal human sweat, J. Lab. Clin. Med. 69:634.

    CAS  PubMed  Google Scholar 

  • Pagel, J. E., and Seyfried, P. L., 1976, Numerical taxonomy of aquatic Acinetobacter isolates, J. Gen. Microbiol. 95:220.

    Google Scholar 

  • Peters, G., and Pulverer, G., 1975, Bacteriophages from micrococci, Zentralbl. Bakteriol. Hyg. Abt. I. Orig. A. 233:221.

    Google Scholar 

  • Pitcher, D. G., 1976, Arabinose with LL-Diaminopimelic acid in the cell wall of an aerobic coryneform organism isolated from human skin, J. Gen. Microbiol. 94:225.

    CAS  PubMed  Google Scholar 

  • Pitcher, D. G., 1977, Rapid identification of cell wall components as a guide to the classification of aerobic coryneform bacteria from human skin, J. Med. Microbiol. 10:439.

    CAS  PubMed  Google Scholar 

  • Potter, B. S., Burgoon, C. F., and Johnson, W. C., 1973, Pityrosporum folliculitis. Report of 7 cases and review of the Pityrosporum organism relative to cutaneous disease, Arch. Dermatol. 107:388.

    CAS  PubMed  Google Scholar 

  • Price, P. B., 1938, The bacteriology of normal skin. A new quantitative test applied to a study of the bacterial flora and the disinfectant action of mechanical cleansing, J. Infect. Dis. 63:301.

    Google Scholar 

  • Puhvel, S. M., Reisner, R. M., and Sakamoto, M., 1975, Analysis of lipid composition of isolated human sebaceous gland homogenates after incubation with cutaneous bacteria. Thin layer chromatography, J. Invest. Dermatol. 64:406.

    CAS  PubMed  Google Scholar 

  • Puleo, J. R., Fields, N. D., Bergstrom, S. L., Oxborrow, G. S., Stabekis, P. D., and Koukol, R. C., 1977, Microbiological profiles of the Viking spacecraft, Appl. Environ. Microbiol. 33:379.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Pulverer, G., and Ko, H. L., 1973, Fermentative and serological studies on Propionibacterium acnes, Appl. Microbiol. 25:222.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Pulverer, G., Pillich, J., and Klein, A., 1975, New bacteriophages of Staphylococcus epidermidis, J. Infect. Dis. 132:524.

    CAS  PubMed  Google Scholar 

  • Roberts, C.D., 1975, The role of bacteria in acne vulgaris, Ph.D. Thesis, University of Leeds.

    Google Scholar 

  • Rogosa, M., Cummins, C. S., Lelliott, R. A., and Keddie, R. M., 1974, Coryneform group of bacteria, in: Bergey’s Manual of Determinative Bacteriology, 8th ed. (R. E. Buchanan and N. E. Gibbons, eds.), Williams and Wilkins, Baltimore.

    Google Scholar 

  • Rook, A., 1977, Common baldness and alopecia areata, in: Recent Advances in Dermatology (A. Rook, ed.), pp. 223–247, Churchill-Livingstone, Edinburgh.

    Google Scholar 

  • Saino, Y., Eda, J., Nagoya, T., Yoshimura, Y., Yamaguchi, M., and Kobayashi, F., 1976, Anaerobic coryneforms isolated from human bone marrow and skin: chemical, biochemical and serological studies and some of their biological activities, Jpn. J. Microbiol. 20:17.

    CAS  PubMed  Google Scholar 

  • Sanderson, P. J., 1977, Infection of the foot with Peptococcus magnus, J. Clin. Pathol. 30:266.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Sarkany, I., and Gaylarde, C. C., 1967, Skin flora of the newborn, Lancet 1:589.

    CAS  PubMed  Google Scholar 

  • Sarkany, I., Taplin, D., and Blank, H., 1961, The etiology and treatment of erythrasma, J. Invest. Dermatol. 37:283.

    CAS  PubMed  Google Scholar 

  • Savin, J. A., 1974, Bacterial infections in diabetes mellitus, Br. J. Dermatol. 91:481.

    CAS  PubMed  Google Scholar 

  • Savin, J. A., and Noble, W. C., 1977, Opportunism and skin infections, in: Recent Advances in Dermatology (A. Rook, ed.), pp. 1–29, Churchill-Livingstone, Edinburgh.

    Google Scholar 

  • Schleifer, K.H., and Kandier, O., 1972, Peptidoglycan types of bacterial cell walls and their taxonomic implications, Bacteriol. Rev. 36:407.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Schleifer, K. H., and Kloos, W. E., 1975, Isolation and characterization of Staphylococci from human skin. I. Amended descriptions of Staphylococcus epidermidis and Staphylococcus saprophyticus and descriptions of three new species: Staphylococcus cohnii, Staphylococcus haemolyticus and Staphylococcus xylosus, Int. J. System. Bacteriol. 25:50.

    CAS  Google Scholar 

  • Schleifer, K. H., and Kocur, M., 1973, Classification of Staphylococci based on chemical and biochemical properties, Arch. Mikrobiol. 93:65.

    CAS  PubMed  Google Scholar 

  • Selwyn, S., 1975, Natural antibiosis among skin bacteria as a primary defence against infection, Br. J. Dermatol. 93:487.

    CAS  PubMed  Google Scholar 

  • Selwyn, S., and Ellis, H., 1972, Skin bacteria and skin disinfection reconsidered, Br. Med. J. 1:136.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Selwyn, S., Marsh, P. D., and Sethna, T. N., 1976, In vitro and in vivo studies on antibiotics from skin micrococcaceae, in: Chemotherapy, vol. 5, p. 391 (J. D. Williams and A. M. Geddes, eds.), Plenum Press, New York and London.

    Google Scholar 

  • Sharpe, M. E., Law, B. A., and Phillips, B. A., 1976, Coryneform bacteria producing methane-thiol, J. Gen. Microbiol. 94:430.

    CAS  Google Scholar 

  • Sharpe, M. E., Law, B. A., Phillips, B. A., and Pitcher, D. G., 1977, Methane-thiol production by coryneform bacteria: strains from dairy and human skin sources and Brevibacterium linens, J. Gen. Microbiol. 101:345.

    CAS  PubMed  Google Scholar 

  • Singh, G., 1974, Heat, humidity and pyodermas, Dermatologica 147:342.

    Google Scholar 

  • Smith, R. F., 1969, Characterisation of human cutaneous lipophilic diptheroids, J. Gen. Microbiol. 55:433.

    CAS  PubMed  Google Scholar 

  • Smith, R. F., 1971, Lactic acid utilization by the cutaneous Micrococcaceae, Appl. Microbiol. 21:777.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Smith, J. M. B., and Marples, M. J., 1964, A natural reservoir of penicillin resistant strains of Staphylococcus aureus, Nature (London) 201:844.

    CAS  Google Scholar 

  • Snell, J. J. S., 1973, The Distribution and Identification of Nonfermenting Bacteria, Public Health Laboratory Service, Monograph 4, London.

    Google Scholar 

  • Somerville, D. A., 1972, A quantitative study of erythrasma lesions, Br. J. Dermatol. 87:130.

    CAS  PubMed  Google Scholar 

  • Somerville, D. A., 1973, A taxonomic scheme for aerobic diphtheroids from human skin, J. Med. Microbiol. 6:215.

    CAS  PubMed  Google Scholar 

  • Somerville, D. A., and Lancaster-Smith, M., 1973, The aerobic cutaneous microflora of diabetic subjects, Br. J. Dermatol. 89:395.

    CAS  PubMed  Google Scholar 

  • Somerville, D. A., and Murphy, C. T., 1973, Quantitation of Corynebacterium acnes on healthy human skin, J. Invest. Dermatol. 60:231.

    CAS  PubMed  Google Scholar 

  • Somerville, D. A., and Noble, W. C., 1970, A note on the Gram negative bacilli of human skin, Eur. J. Clin. Biol. Res. 15:669.

    CAS  Google Scholar 

  • Somerville-Millar, D. A., and Noble, W. C., 1974, Resident and transient bacteria of the skin, J. Cutan. Pathol. 1:260.

    CAS  PubMed  Google Scholar 

  • Stanneck, J. L., and Roberts, G. D., 1974, Simplified approach to identification of aerobic actinomycetes by thin-layer chromatography, Appl. Microbiol. 28:226.

    Google Scholar 

  • Stratford, B., Gallus, A. S., Matthieson, A. H., and Dixson, S., 1968, Alteration of superficial bacterial flora in severely ill patients, Lancet 1:68.

    CAS  PubMed  Google Scholar 

  • Strauss, J. S., Pochi, P. E., and Downing, D. T., 1976, The role of skin lipids in acne, Cutis 17:485.

    CAS  PubMed  Google Scholar 

  • Stringer, M. F., and Marples, R. R., 1976, Ultrasonic methods for sampling human skin microorganisms, Br. J. Dermatol. 94:551.

    CAS  PubMed  Google Scholar 

  • Subcommittee on Taxonomy of Staphylococci and Micrococci, 1965, Int. Bull. Bacteriol. Nomencl. Taxon. 15:107.

    Google Scholar 

  • Tagg, J. R., Dajani, A. S., and Wannamaker, L. W., 1976, Bacteriocins of gram positive bacteria, Bacteriol. Rev. 40:722.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Talbot, H. W., and Parisi, J. T., 1976, Phage typing of Staphylococcus epidermidis, J. Clin. Microbiol. 3:519.

    PubMed Central  PubMed  Google Scholar 

  • Valtonen, M. V., Valtonen, V. V., Salo, O. P., and Makela, P. H., 1976, The effect of long term tetracycline treatment for acne vulgaris on the occurrence of R factors in the intestinal flora of man, Br. J. Dermatol. 95:311.

    CAS  PubMed  Google Scholar 

  • Voss, J. G., 1970, Differentiation of two groups of Corynebacterium acnes, J. Bacteriol. 101:392.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Voss, J. G., 1974, Acne vulgaris and free fatty acids. A review and criticism, Arch. Dermatol. 109:894.

    CAS  PubMed  Google Scholar 

  • Williamson, P., and Kligman, A. M., 1965, A new method for the quantitative investigation of cutaneous bacteria, J. Invest. Dermatol. 45:498.

    CAS  PubMed  Google Scholar 

  • Wiseman, G. M., 1975, The hemolysins of Staphylococcus aureus, Bacteriol. Rev. 39:317.

    CAS  PubMed Central  PubMed  Google Scholar 

  • Wolff, H. H., and Plewig, G., 1976, Ultrastruktur der Mikroflora in Follikeln und Komedonen, Hautarzt 27:432.

    CAS  PubMed  Google Scholar 

  • Youssef, N., Wyborn, C. H. E., Holt, G., Noble, W. C., and Clayton, Y. M., 1978, Antibiotic production by dermatophyte fungi,J. Gen. Microbiol. 105:105.

    CAS  PubMed  Google Scholar 

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Noble, W.C., Pitcher, D.G. (1978). Microbial Ecology of the Human Skin. In: Alexander, M. (eds) Advances in Microbial Ecology. Advances in Microbial Ecology, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-8222-9_6

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