Abstract
Cholesterol is solubilized and condensed in the monomolecular hydrophobic shell of AOT reverse micellar droplet; the degree of condensation increases with increase in concentration of cholesterol. Saturation is attained when the concentration of cholesterol is 50% of the surfactant in the system. The condensation is a spontaneous process and the extent of saturation is surprisingly the same as observed in cholesterol-biological membrane system. The present study suggests that the surfactant monolayer of w/o microemulsion droplet can be used well as a model for biological membranes for studies of solubilization of extramembraneous components.
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Maitra, A., Patanjali, P.K. (1986). Reverse Micelle as Membrane Mimetic Agent — A Study of Cholesterol Solubilization in Water-Aerosol OT-Isooctane System. In: Mittal, K.L., Bothorel, P. (eds) Surfactants in Solution. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7981-6_2
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DOI: https://doi.org/10.1007/978-1-4615-7981-6_2
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