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Laser Effects on Normal and Tumor Tissue

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Laser Applications in Medicine and Biology

Abstract

Early reports of experimental and clinical applications, using the intense, coherent, monochromatic laser energy for selected surgical procedures, were published by McGuff et al. (1963) and Helsper et al. (1964). In some instances these observations suggested that ruby laser energy (694.3 nm) partially destroyed tumor tissue which, later, was followed by a delayed remission of the entire tumor. Permanent tumor cures were obtained on certain strains of transplanted melanoma growing in laboratory animals. A year later, McGuff et al. (1964) reported the successful destruction of subcutaneous human tumor, and Goldman et al. (1964) nevi and melanomas. Enthusiasm in surgical research was sparked by such successes but was constrained by the limited availability of suitable apparatus and qualified technical personnel.

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Author information

Authors and Affiliations

  1. Biomedical Engineering and Instrumentation Branch Division of Research Services, National Institutes of Health, Bethesda, Maryland, USA

    Grant C. Riggle

  2. Surgery Branch National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA

    Robert C. Hoye & Alfred S. Ketcham

Authors
  1. Grant C. Riggle
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  2. Robert C. Hoye
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  3. Alfred S. Ketcham
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Editor information

Editors and Affiliations

  1. Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina, USA

    M. L. Wolbarsht (Professor of Ophthalmology and Director of Research) (Professor of Ophthalmology and Director of Research)

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© 1971 Plenum Press, New York

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Riggle, G.C., Hoye, R.C., Ketcham, A.S. (1971). Laser Effects on Normal and Tumor Tissue. In: Wolbarsht, M.L. (eds) Laser Applications in Medicine and Biology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7320-3_3

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  • DOI: https://doi.org/10.1007/978-1-4615-7320-3_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-7322-7

  • Online ISBN: 978-1-4615-7320-3

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