Abstract
Breast cancer is the leading cause of cancer death in American women. Over the past 80 years this malignancy has been studied intensively not only because of its high incidence, but also because of interest generated by the original observation of Beatson demonstrating that some tumors are hormone dependent. Unfortunately, it has only been over the past decade that real advances have been made in the treatment of this disease, as well as in our understanding of breast tumor biology and natural history.
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References
G. T. Beatson, On treatment of inoperable cases of carcinoma of mamma. Suggestions for a new method of treatment with illustrative cases, Lancet 2: 104 (1896).
B. A. Stoll, “Hormonal Management in Breast Cancer,” J. B. Lippincott, Philadelphia (1969).
W. L. McGuire, P. P. Carbone, and E. P. Vollmer, “Estrogen Recep- tors in Human Breast Cancer,” Raven Press, New York (1975).
C. K. Osborne and W. L. McGuire, Current use of steroid hormone receptor assays in the treatment of breast cancer, Surg. Clinics N. Amer 58: 777 (1978).
K. B. Horwitz, W. L. McGuire, O. H. Pearson, and A. Segaloff, Predicting response to endocrine therapy in human breast cancer: A hypothesis, Science 189: 726 (1975).
W. A. Knight, R. B. Livingston, E. J. Gregory, and W. L. McGuire, Estrogen receptor is an independent prognostic factor for early recurrence in breat cancer. Cancer Res. 37: 4669 (1977).
E. R. DeSombre, G. L. Greene, and E. V. Jensen, in “Hormones, Receptors, and Breast Cancer” (W. L. McGuire, ed.), pp. 1–14, Raven Press, New York (1978).
M. A. Rich, P. Furmanski, and S. C. Brooks, Prognostic value of estrogen receptor determinations in patients with breast cancer, Cancer Res. 38: 4296 (1978).
J. C. Allegra, M. E. Lippman, R. Simon, E. B. Thompson, A. Barlock, L. Green, K. K. Huff, H. M. T. Do, S. C. Aitken, and R. Warren, Association between steroid hormone receptor status and disease-free interval in breast cancer, Cancer Treat. Rep 63: 1271 (1979).
P. V. Maynard, R. W. Blamey, C. W. Elston, J. L. Haybittle, and K. Griffiths, Estrogen receptor assay in primary breast cancer and early recurrence of the disease, Cancer Res. 38: 4292 (1978).
H. M. Bishop, C. W. Elston, R. W. Blarney, J. L. Haybittle, R. I.Nicholson, and K. Griffiths, Relationship of oestrogen-receptor status of survival in breast cancer, Lancer 2: 283 (1979).
T. Booke, R. Shields, D. George, P. Maynard, and K. Griffiths, Oestrogen receptors and prognosis in early breast cancer, Lancer 2: 995 (1979).
R. Hahnel, T. Woodings, A. B. Vivian, Prognostic value of estrogen receptors in primary breast cancer, Cancer 44: 671 (1979).
J. S. Meyer, W. C. Bauer, and B. R. Rao, Subpopulations of breast caricnoma defined by S-phase fraction, morphology, and estrogen receptor content, Lab. Investig. 39: 225 (1978).
J. S. Meyer, B. R. Rao, S. C. Stevens, and W. L. White, Low incidence of estrogen receptor in breast carcinomas with rapid rates of cellular replication, Cancer 40: 2290 (1977).
R. Silvestrini, M.G. Daidone, and G. DiFronzo, Relationship between proliferative activity and estrogen receptors in breast cancer, Cancer 44: 665 (1979).
E. R. Fisher, C. K. Redmond, H. Lin, H. Rockette, and B. Fisher, Correlation of estrogen receptor and pathologic characteristics of invasive breast cancer, Cancer in press, 1980.
E. R. Fisher, R. M. Gregorio, and B. Fisher, The pathology of invasive breast cancer. A syllabus derived from findings of the National Surgical Adjuvant Breast Project (Protocol No. 4), Cancer 36: 1, (1975).
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© 1982 Plenum Press, New York
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Osborne, C.K., Fisher, E., Redmond, C., Knight, W.A., Yochmowitz, M.G., McGuire, W.L. (1982). Estrogen Receptor, a Marker for Human Breast Cancer Differentiation and Patient Prognosis. In: Leavitt, W.W. (eds) Hormones and Cancer. Advances in Experimental Medicine and Biology, vol 138. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7192-6_23
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DOI: https://doi.org/10.1007/978-1-4615-7192-6_23
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