Abstract
Polarographic electrodes have been used for many years to measure oxygen partial pressure (pO2) in various organs and tissues, often in animal experiments, and have greatly contributed to the understanding of local mechanisms controlling tissue oxygen supply. Five years ago we reported the use of a hydrogen clearance technique using a multichannel electrode (Kessler & Lübbers, 1966, multiwire surface electrode, MDO) adapted to the detection of partial pressure of hydrogen (pH2) in order to measure capillary blood flow in skeletal muscle (Harrison & Kessler, 1989a). This development meant that measurements of both blood flow and pO2 could be made in similar volumes of tissue. Furthermore, methods were devised whereby local O2 uptake rate could be calculated (Harrison et al. 1989; Harrison et al. 1990).
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© 1997 Springer Science+Business Media New York
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Harrison, D.K. (1997). Catchment Depths of Surface Electrodes for H2 and O2 in Tissue. In: Nemoto, E.M., et al. Oxygen Transport to Tissue XVIII. Advances in Experimental Medicine and Biology, vol 411. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5865-1_68
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DOI: https://doi.org/10.1007/978-1-4615-5865-1_68
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