Abstract
Diabetes is strongly associated with an accelerated rate of development of atherosclerosis1. Evidence suggests that elevated serum glucose levels may contribute to atherogenesis in diabetic patients by promoting oxidation of lipoproteins, propagation of free radicals, and production of advanced glycation end-products (AGE)2 3 4. However, the exact mechanisms of how hyperglycemia accelerates atherogenesis are not understood.
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Hedrick, C.C., Kim, M.D., Natarajan, R.D., Nadler, J.L. (1999). 12-Lipoxygenase Products Increase Monocyte: Endothelial Interactions. In: Honn, K.V., Marnett, L.J., Nigam, S., Dennis, E.A. (eds) Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 4. Advances in Experimental Medicine and Biology, vol 469. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4793-8_67
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DOI: https://doi.org/10.1007/978-1-4615-4793-8_67
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