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Urothelial Differentiation and Bladder Cancer

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Advances in Bladder Research

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 462))

Abstract

Cancer is the endpoint of a multi-step process of carcinogenesis.1–5 This process involves multiple genetic and epigenetic alterations and cellular selections.2–4,6 These changes result in cell populations with unregulated growth and ultimately, the ability to invade and metastasize. Many of these cancer cell characteristics may reflect a loss of the regulation present during the normal differentiation process.7

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Authors and Affiliations

  1. Departments of Urology and Cell Biology, The University of Texas-M.D. Anderson Cancer Center, Houston, Texas, 77098, USA

    Monica Liebert, Daniel Gebhardt, Christopher Wood, I-Ling Lee Chen, Jeffrey Ellard, Daniel Amancio & H. Barton Grossman

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  1. Monica Liebert
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  2. Daniel Gebhardt
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  3. Christopher Wood
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  4. I-Ling Lee Chen
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  5. Jeffrey Ellard
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  6. Daniel Amancio
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  7. H. Barton Grossman
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Editor information

Editors and Affiliations

  1. Department of Urology, University of California, San Francisco, USA

    Laurence S. Baskin  & Simon W. Hayward  & 

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Liebert, M. et al. (1999). Urothelial Differentiation and Bladder Cancer. In: Baskin, L.S., Hayward, S.W. (eds) Advances in Bladder Research. Advances in Experimental Medicine and Biology, vol 462. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4737-2_34

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  • DOI: https://doi.org/10.1007/978-1-4615-4737-2_34

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7147-2

  • Online ISBN: 978-1-4615-4737-2

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