Skip to main content

Clinical Efficacy of Platelet Concentrates

  • Chapter
Coagulation and Blood Transfusion

Part of the book series: Developments in Hematology and Immunology ((DIHI,volume 26))

Abstract

Clinical efficacy of platelet concentrates is related to the ability of platelet concentrates (PC) to control or prevent bleeding in thrombocytopenic patients. It has to be separated from quality.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  1. Snijder EL, Morroff G, Heaton A, and members of the Ad Hoc Platelet Radiolabeling Study Group. Recommended methods for conducting radiolabeled platelet survival studies. Transfusion; 1986:26.37–42

    Article  Google Scholar 

  2. Rock G, Tittley P. A comparison of results obtained by two different chromium-51 methods of determining platelet survival and recovery. Transfusion 1990;30:407–10.

    Article  PubMed  CAS  Google Scholar 

  3. Harker LA, Slichter SJ. The bleeding time as a screening test for evaluation of platelet function. N Engl J Med 1972;287:155–9.

    Article  PubMed  CAS  Google Scholar 

  4. Gaydos LA, Freireich EJ, Mantel N. The quantitative relation between platelet count and hemorrhage in patients with acute leukemia. N Engl J Med 1962;266:905–9.

    Article  PubMed  CAS  Google Scholar 

  5. Slichter SJ, Harker LA. Thrombocytopenia: Mechanism and management of defects in platelet production. Clin Haematol 1978;7:523–39.

    PubMed  CAS  Google Scholar 

  6. Freireich EJ, Schmidt PJ, Schneiderman MA, Frei E. A comparative study of the effect of transfusion of fresh and preserved whole blood on bleeding in patients with acute leukemia. N Engl J Med 1959;260:6–11.

    Article  PubMed  CAS  Google Scholar 

  7. Freireich EJ, Kliman A, Gaydos LA, Mantel N, Frei EA. Response to repeated platelet transfusion from the same donor. Ann Int Med 1963;59: 277–87.

    PubMed  CAS  Google Scholar 

  8. Alvarado J, Djerassi I, Farber S. Transfusion of fresh concentrated platelets to children with acute leukemia. J Pediatr 1965;67:13–22.

    Article  PubMed  CAS  Google Scholar 

  9. Van Eys J, Thomas D, Olivos B. Platelet use in pediatric oncology: A review of 393 transfusions. Transfusion 1978;18:169–73.

    Article  PubMed  Google Scholar 

  10. Roy AJ, Jaffe N, Djerassi I. Prophylactic platelet transfusion in children with acute leukemia: A dose response study. Transfusion 1973;13:283–90.

    Article  PubMed  CAS  Google Scholar 

  11. Higby DJ, Cohen E, Holland JF, Sinks L. The prophylactic treatment of thrombocytopenic leukemic patients with platelets: A double blind study.Transfusion 1974;14:440–6.

    Article  PubMed  CAS  Google Scholar 

  12. Solomon J, Bofenkamp T, Fahey JL, Chillar RK, Beutler E. Platelet profylaxis in acute non-lymphoblastic leukemia. Lancet 1978;i:267.

    Article  Google Scholar 

  13. Murphy S, Litwin S, Herring LM, et al. Indications for platelet transfusion in children with acute leukemia. Am J Hematol 1982;12:347–56.

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1991 Springer Science+Business Media Dordrecht

About this chapter

Cite this chapter

de Wolf, J.T.M. (1991). Clinical Efficacy of Platelet Concentrates. In: Sibinga, C.T.S., Das, P.C., Mannucci, P.M. (eds) Coagulation and Blood Transfusion. Developments in Hematology and Immunology, vol 26. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3900-1_15

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-3900-1_15

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6740-6

  • Online ISBN: 978-1-4615-3900-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics