Abstract
OR-1259 is a positive inotropic and vasodilatory compound with antiarrhythmic properties. Biochemically, OR-1259 can act as a troponin modifier, as an phosphodiesterase III inhibitor and as an inhibitor of voltage-sensitive Ca2+ current.
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© 1992 Springer Science+Business Media New York
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Raasmaja, A., Talo, A., Haikala, H., Nissinen, E., Lindén, IB., Pohto, P. (1992). Biochemical Properties of OR-1259 - A Positive Inotropic and Vasodilatory Compound with an Antiarrhythmic Effect. In: Frank, G.B., Bianchi, C.P., ter Keurs, H.E.D.J. (eds) Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle. Advances in Experimental Medicine and Biology, vol 311. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3362-7_63
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DOI: https://doi.org/10.1007/978-1-4615-3362-7_63
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-6483-2
Online ISBN: 978-1-4615-3362-7
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