Abstract
During the course of the joint project of the European Community towards realisation of a clinical facility for treating patients with BNCT, an epithermal neutron beam has been developed at the High Flux Reactor in Petten. This is designed for use in treating deep-seated brain tumours such as glioblastomas and astrocytomas through the intact skin (and skull). This paper covers the initial studies of epithermal irradiation and boron neutron capture using a canine model and borocaptate sodium (BSH) as boron carrier. The goal of this investigation is the estimation of the tolerance of normal tissues, such as brain, skin and bone marrow.
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References
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© 1993 Springer Science+Business Media New York
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Philipp, K.H.I., Gavin, P.R., Casado, J., Siefert, A., Moss, R.L., Huiskamp, R. (1993). Developments in Healthy Tissue Tolerance Studies as a Precondition for Clinical Application of Boron Neutron Capture Therapy. In: Soloway, A.H., Barth, R.F., Carpenter, D.E. (eds) Advances in Neutron Capture Therapy. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2978-1_115
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DOI: https://doi.org/10.1007/978-1-4615-2978-1_115
Publisher Name: Springer, Boston, MA
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