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The Effect of Human Dendritic Cells on the Lectin-Induced Responsiveness of CD4+ T Cells To IL-2 and IL-4

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Dendritic Cells in Fundamental and Clinical Immunology

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 329))

Abstract

Human peripheral blood dendritic cells (DC) are potent accessory cells (AC) for the lectin-induced proliferative response of T lymphocytes1. However, the contribution of DC to the responsiveness of lectin-induced T cells to IL-2 and IL-4 is not clearly understood. The AC-dependent induction of IL-2 responsiveness by mitogenic lectin has been reported2. It has been also shown that the proliferation of lectin-induced T cells is promoted bv IL-2 or IL-4 in the absence of AC.3

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© 1993 Plenum Press, New York

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Markowicz, S., Mehta, A. (1993). The Effect of Human Dendritic Cells on the Lectin-Induced Responsiveness of CD4+ T Cells To IL-2 and IL-4. In: Kamperdijk, E.W.A., Nieuwenhuis, P., Hoefsmit, E.C.M. (eds) Dendritic Cells in Fundamental and Clinical Immunology. Advances in Experimental Medicine and Biology, vol 329. Springer, New York, NY. https://doi.org/10.1007/978-1-4615-2930-9_13

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  • DOI: https://doi.org/10.1007/978-1-4615-2930-9_13

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4613-6272-2

  • Online ISBN: 978-1-4615-2930-9

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