Abstract
Desmopressin (DDAVP) is the treatment of first-choice for the management of patients with mild hemophilia A and von Willebrand disease1,2. This agent is cheap and safe and it is useful in about 80 % of cases. DDAVP has had a major impact in the therapeutic efforts for the prevention and treatment of bleeding in such patients. Since its introduction for clinical use3, the large majority of patients with these disorders can safely avoid the use of blood products (cryoprecipitate, commercial factor VIII concentrates), that, although rendered almost completely safe by virucidal methods, still have a potential risk of transmitting blood-borne viruses4,5.
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References
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Castaman, G., Ruggeri, M., Bona, E.D., Rodeghiero, F. (1993). Management of Spontaneous Bleeding and Prevention of Bleeding After Dental Extractions and Other Surgical Procedures in Mild Hemophilia a and Von Willebrand’s Disease: Ten Years of Experience at the Vicenza Hemophilia and Thrombosis Center. In: Mariani, G., Mannucci, P.M., Cattaneo, M. (eds) Desmopressin in Bleeding Disorders. NATO ASI Series, vol 242. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2922-4_29
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DOI: https://doi.org/10.1007/978-1-4615-2922-4_29
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