Abstract
The production of hematopoietic cells in blood-forming organs requires interaction between progenitor cells and stromal elements. The ability of these early cells to differentiate along multiple lineages can be experimentally reproduced in vitro. This is the case for myelopoiesis and B lymphocyte production where convenient in vitro stem cell assays in both murine and human models (1, 2) are available.
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© 1994 Springer Science+Business Media New York
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De Smedt, M., Leclercq, G., Vandekerckhove, B., Plum, J. (1994). Human Fetal Liver Cells Differentiate Into Thymocytes in Chimeric Mouse Fetal Thymus Organ Culture. In: Heinen, E., Defresne, M.P., Boniver, J., Geenen, V. (eds) In Vivo Immunology. Advances in Experimental Medicine and Biology, vol 355. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2492-2_5
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DOI: https://doi.org/10.1007/978-1-4615-2492-2_5
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