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Electrocardiographic Predictors of Coronary Heart Disease in the Seven Countries Study

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Prevention of Coronary Heart Disease: Diet, Lifestyle and Risk Factors in the Seven Countries Study

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 243))

Abstract

The electrocardiogram (ECG) displays information about the heart, whether there has been a heart attack or the muscle lacks oxygen, whether conduction of the heart beat is disturbed or its rate or rhythm altered. It is useful as a rapid indicator of the diagnosis and is easy, painless and inexpensive to record. Also used to monitor severely ill patients, the record made in healthy people at rest or undergoing an exercise test helps predict risk of future coronary disease.

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References

  1. Blackburn H, Keys A, Simonson E, Rautaharju P, Punsar S. The electrocardiogram in population studies: a classification system. Circulation 1960;21:1160–1175.

    Article  PubMed  CAS  Google Scholar 

  2. Rose G, Blackburn H. Cardiovascular Survey Methods. World Health Organization, Geneva, 1968:1–188.

    Google Scholar 

  3. Keys A (Ed). Coronary heart disease in seven countries. Circulation 1970; 41 Suppl 1: 1211.

    Google Scholar 

  4. Menotti A, Mulder I, Kromhout D, Nissinen A, Feskens EJM, Giampaoli S. The association of silent electrocardiographic findings with coronary deaths among elderly men in three European countries. The FINE study. Acta Cardiol 2001; 56: 27–36.

    Article  PubMed  CAS  Google Scholar 

  5. Dekker J, Schouten EG, Kromhout D, Klootwijk P, Pool J. The Cardiac Infarction Injury Score and coronary heart disease in middle-aged and elderly men: the Zutphen Study. J Clin Epidemiol 1995; 48: 833–840.

    Article  PubMed  CAS  Google Scholar 

  6. Dekker J, Schouten EG, Klootwijk P, Pool J, Kromhout D. Association between QT interval and coronary heart disease in middle-aged and elderly men. The Zutphen Study. Circulation 1994; 90: 770–785.

    Article  Google Scholar 

  7. Dekker J, Feskens EJ, Schouten EG, Klootwijk P, Pool J, Kromhout D. QTc duration is associated with levels of insulin and glucose intolerance. The Zutphen Elderly Study. Diabetes 1996; 45: 376–380.

    Article  PubMed  CAS  Google Scholar 

  8. Dekker J, Schouten EG, Klootwijk P, Pool J, Kromhout D. ST segment and T wave characteristics as indicators of coronary heart disease risk: the Zutphen Study. J Am Coll Cardiol 1995; 25: 1321–1326.

    Article  PubMed  CAS  Google Scholar 

  9. Dekker J, Schouten EG, Klootwijk P, Pool J, Swenne CA, Kromhout D. Heart rate variability from short electrocardiographic recordings predicts mortality from all causes in middle-aged and elderly men. The Zutphen Study. Am J Epidemiol 1997; 145: 899–908.

    Article  PubMed  CAS  Google Scholar 

  10. Lanti M, Puddu PE, Menotti A. Voltage criteria of left ventricular hypertrophy in sudden and non-sudden coronary artery disease mortality: the Italian section of the Seven Countries Study. Am J Cardiol 1990; 15: 1181–1185.

    Article  Google Scholar 

  11. Rabkin SW, Mathewson FAL, Tate RB. The electrocardiogram in apparently healthy men and the risk of sudden death. Br Heart J 1982;47:546–552.

    Article  PubMed  CAS  Google Scholar 

  12. Cullen K, Stenhouse NS, Wearne KL, Cumpston GN. Electrocardiograms and 13-year cardiovascular mortality in the Busselton Study. Br Heart J 1982;47:209–212.

    Article  PubMed  CAS  Google Scholar 

  13. Cedres BL, Liu K, Stamler J, Dyer AR, Stamler R, Berkson DM, Paul O, Lepper M, Lindberg HA, Marquardt J, Stevens E, Schoenberger JA, Shekelle RB, Collette P, Garside D. Independent contribution of electrocardiographic abnormalities to risk of death from coronary heart disease, cardiovascular disease and all causes. Findings of three Chicago epidemiologic studies. Circulation 1982;65:146–153.

    Article  PubMed  CAS  Google Scholar 

  14. Brand FN, Abbott RD, Kannel WB, Wolf PA. Characteristics and prognosis of lone atrial fibrillation. 30-year follow-up in the Framingham Study. JAMA 1985;254:3449–3453.

    Article  PubMed  CAS  Google Scholar 

  15. Liao Y, Liu K, Dyer A, Schoenberger JA, Shekelle RB, Colette P, Stamler J. Major and minor electrocardiographic abnormalities and risk of death from coronary heart disease, cardiovascular diseases and all causes in men and women. J Am Coll Cardiol 1988;12:1494–1500.

    Article  PubMed  CAS  Google Scholar 

  16. Levy D, Labib SB, Anderson KM, Christiansen JC, Kannel WB, Castelli WP. Determinants of sensitivity and specificity of electrocardiographic criteria for left ventricular hypertrophy. Circulation 1990;81:1144–1146.

    Article  Google Scholar 

  17. Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke 1991;22:983–988.

    Article  PubMed  CAS  Google Scholar 

  18. Kannel WB, Cobb J. Left ventricular hypertrophy and mortality. Results from the Framingham Study. Cardiology 1992;81:291–298.

    Article  PubMed  CAS  Google Scholar 

  19. Furberg CD, Manolio T, Psaty BM, Bild DE, Borhani NO, Newman A, Tabatznik B, Rautaharju PM. Major electrocardiographic abnormalities in persons aged 65 years and older (the Cardiovascular Health Study). Cardiovascular Health Study Collaborative Research Group. Am J Cardiol 1992; 69: 1329–1335

    Article  PubMed  CAS  Google Scholar 

  20. Sutherland SE, Gazes PC, Keil JE, Gilbert GE, Knapp RG. Electrocardiographic abnormalities and 30-year mortality among white and black men of the Charleston Heart Study. Circulation 1993;88:2685–2692.

    Article  PubMed  CAS  Google Scholar 

  21. De Bacquer D, Martins-Pereira LS, De Backer G, De Henauw S, Kornitzer M. The predictive value of electrocardiographic abnormalities for total and cardiovascular disease mortality in men and women. Eur Heart J 1994;15:1604–1610.

    PubMed  Google Scholar 

  22. Iacovino JR. Mortality analysis of complete right and left bundle branch block in a selected community population. J Insur Med 1997; 29: 91–99.

    PubMed  CAS  Google Scholar 

  23. Greenland P, Xie X, Liao Y, Daviglus M, Walsh M, Stamler J. Isolated nonspecific resting ECG ST and/or T abnormalities predict 22-year risk of cardiovascular death in men and women: the Chicago Heart Association Detection Project in Industry [abstract]. Can J Cardiol 1997;13 Suppl B:372.

    Google Scholar 

  24. Menotti A, Seccareccia F and the RIFLE Research Group. Electrocardiographic Minnesota Code findings predicting short term mortality in asymptomatic subjects. The Italian RIFLE Pooling Project (Risk Factors and Life Expectancy) G Ital Cardiol 1997;27:40–49.

    PubMed  CAS  Google Scholar 

  25. De Bruyne MC, Mosterd A, Hoes AW, Kors JA, Kruijssen DA, Van Bemmel JH, Hofman A, Grobbee DE. Prevalence, determinants, and misclassification of myocardial infarction in the elderly. Epidemiol 1997; 8: 495–500.

    Article  Google Scholar 

  26. De Bacquer D, De Backer G, Kornitzer M, Myny K, Doyen Z, Blackburn H. Prognostic value of ischemic electrocardiographic findings for cardiovascular mortality in men and women. J Am Coll Cardiol 1999;33:1491–1498.

    Article  PubMed  Google Scholar 

  27. Ashley, EA, Raxwal VK, Froelicher VF. The prevalence and prognostic significance of electrocardiographic abnormalities. Probl Cardiol 2000;21:1–72.

    Article  Google Scholar 

  28. Wilhelmsen L, Bjure J, Ekstrom-Jodal, B, Aurell M, Grimby G, Scardsudd K, Tibblin G, Wedel H. Nine years’ follow-up of a maximal exercise test in random population sample of middle-aged men. Cardiology 1981; 68 Suppl 2: 1–8.

    Article  PubMed  Google Scholar 

  29. Bruce RA, Hossack KF, DeRouen TA, Hofer V. Enhanced risk assessment for primary coronary heart disease events by maximal exercise testing: 10 years’ experience of Seattle Heart Watch. J Am Coll Cardiol 1983; 2: 565–573.

    Article  PubMed  CAS  Google Scholar 

  30. Rautaharju PM, Prineas RJ, Eifler WJ, Furberg CD, Neaton JD, Crow RS, Stamler J, Cutler JA for the MRFIT Research Group. Prognostic value of exercise electrocardiogram in men at high risk of future coronary heart disease: Multiple Risk Factor Intervention Trial experience. J Am Coll Cardiol 1986; 8: 1–10

    Article  PubMed  CAS  Google Scholar 

  31. Bruce RA, Fisher LD. Exercise-enhanced assessment of risk factors for coronary heart disease in healthy men. J Electrocardiography 1987; 20 Suppl: 162–166.

    Article  Google Scholar 

  32. Rautaharju PM, Neaton JD. Electrocardiographic abnormalities and coronary heart disease mortality among hypertensive men in the Multiple Risk Factor Intervention Trial. Clin Invest Med 1987; 10: 606–615.

    PubMed  CAS  Google Scholar 

  33. Ekelund LG, Suchindran CM, McMahon RP, Heiss G, Leon AS, Romhilt DW, Rubenstein CL, Probstfield JL, Ruwitch JF. Coronary heart disease morbidity and mortality in hypercholesterolemic men predicted from an exercise test: the Lipid Research Clinics Coronary Primary Prevention Trial. J Am Coll Cardiol 1989; 14: 556–563.

    Article  PubMed  CAS  Google Scholar 

  34. Siscovick DS, Ekelund LG, Johnson JL, Troung Y, Adler A. Sensitivity of exercise electrocardiography for acute cardiac events during moderate and strenuous physical activity. The Lipid Research Clinics Coronary Primary Prevention Trial. Arch Intern Med 1991; 151: 325–330.

    Article  PubMed  CAS  Google Scholar 

  35. Pedersen F, Sandoe E, Laekerborg A. Prevalence and significance of an abnormal exercise ECG in asymptomatic males. Outcome of thallium myocardial scintigraphy. Eur Heart J 1991; 12: 766–769.

    PubMed  CAS  Google Scholar 

  36. Fleg JL. Prevalence and prognostic significance of exercise-induced silent myocardial ischemia in apparently healthy subjects. Am J Cardiol 1992; 69: 14B–18B.

    Article  PubMed  CAS  Google Scholar 

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Authors
  1. Alessandro Menotti
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  2. Henry Blackburn
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Editor information

Editors and Affiliations

  1. Director Nutrition and Consumer Safety Division, National Institute of Public Health and the Environment, P.O. Box 1, Bilthoven, 3720 BA, The Netherlands

    Daan Kromhout (Professor) (Professor)

  2. Association for Cardiac Research Cardioricerca, Via Adda 87, Rome, 00198, Italy

    Alessandro Menotti (Professor) (Professor)

  3. Division of Epidemiology, School of Public Health University of Minnesota, 1300 South Second Street, Minneapolis, MN, 55454-1015, USA

    Henry Blackburn (Mayo Professor Emeritus) (Mayo Professor Emeritus)

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© 2002 Springer Science+Business Media New York

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Menotti, A., Blackburn, H. (2002). Electrocardiographic Predictors of Coronary Heart Disease in the Seven Countries Study. In: Kromhout, D., Menotti, A., Blackburn, H. (eds) Prevention of Coronary Heart Disease: Diet, Lifestyle and Risk Factors in the Seven Countries Study. Developments in Cardiovascular Medicine, vol 243. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1117-5_14

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  • DOI: https://doi.org/10.1007/978-1-4615-1117-5_14

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  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5402-4

  • Online ISBN: 978-1-4615-1117-5

  • eBook Packages: Springer Book Archive

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