Skip to main content

Development of Targeted Viral Vectors for Cardiovascular Gene Therapy

  • Chapter
Genetic Engineering

Part of the book series: Genetic Engineering: Principles and Methods ((GEPM,volume 25))

Abstract

In recent years, advancement in the development of gene transfer techniques as well as identification of target genes for numerous disorders of both acquired and inherited nature has driven an explosion of published work in the field of gene therapy. Gene therapy has enormous potential to provide new treatments that strike directly at the heart of molecular defects to produce the next generation of molecular medicines in diseases for which current therapy is insufficient or absent.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Isner, J. M., Vale, P. R., Symes, J. F. and Losordo, D. W. (2001)Circ. Res. 89, 389–400.

    PubMed  CAS  Google Scholar 

  2. Herz, J. and Gerard, R. D. (1993) Proc. Nat. Acad. Sci. U.S.A. 90, 2812–2816.

    CAS  Google Scholar 

  3. Kozarsky, K. F., Jooss, K., Donahee, M., Strauss, J. F. and Wilson, J. M. (1996)Nature Genet. 13, 54–62.

    PubMed  CAS  Google Scholar 

  4. Stevenson, S. C., Marshall-Neff, J., Teng, B., Lee, C. B., Roy, S. and McClelland, A.(1995) Arterio. Thromb. Vasc. Biol. 15, 479–484.

    CAS  Google Scholar 

  5. Grossman, M., Radr, D. J., Muller, D. W. M., Kolansky, D. M., Kozarsky, K., Clark, B. J., Stein, E. A., Lupien, P. J., Brewer, H. B., Raper, S. E. and Wilson, J. M. (1995)Nature Med. 1, 1148–1154.

    PubMed  CAS  Google Scholar 

  6. Grossman, H., Raper, S. E., Kozarsky, K., Stein, E. A., Engelhardt, J., Muller, D. W. M.,Lupien, P. J. and Wilson, J. M. (1994)Nature Genet. 6, 335–344.

    PubMed  CAS  Google Scholar 

  7. Spady, D. K., Cuthbert, J. A., Willard, M. N. and Meidell, R. S. (1995)J. Clin. Invest. 96,700–709.

    PubMed  CAS  Google Scholar 

  8. Morishita, R., Yamada, S., Yamamoto, K., Tomita, N., Kida, I., Sakurabayashi, I., Kikuchi, A., Kaneda, Y., Lawn, R., Higaki, J. and Ogihara, T. (1998)Circulation 98, 1898–1904.

    PubMed  CAS  Google Scholar 

  9. Oka, K., Pastore, L., Kim, I. H., Merched, A., Nomura, S., Lee, H. J., Merched-Sauvage, M., Arden-Riley, C., Lee, B., Finegold, M., Beaudet, A. and Chan, L. (2001)Circulation 103,1274–81.

    PubMed  CAS  Google Scholar 

  10. Chen, S.-J., Rader, D. J., Tazelaar, J., Kawashiri, M.-A., Gao, G.-P. and Wilson, J. M.(2001)Mol. Ther. 2, 256–261.

    Google Scholar 

  11. Kim, I.-H., Jozkowicz, A., Piedra, P. A., Oka, K. and Chan, L. (2001) Proc. Nat. Acad.Sci. U.S.A. 98, 13282–13287.

    CAS  Google Scholar 

  12. Huard, J., Lochmuller, H., Acsadi, G., Jani, A., Massie, B. and Karpati, G. (1995)Gene Ther. 2, 107–115.

    PubMed  CAS  Google Scholar 

  13. Kochanek, S., Clemens, P. R., Mitani, K., Chen, H.-H., Chan, S. and Caskey, C. T.(1996) Proc. Nat. Acad. Sci. U.S.A. 93, 5731–5736.

    CAS  Google Scholar 

  14. Kochanek, S. (1999)Hum. Gene Ther. 10, 2451–2459.

    PubMed  CAS  Google Scholar 

  15. Qiao, J. H., Xie, P. Z., Fishbein, M. C., Kreuzer, J., Drake, T. A., Demer, L. L. and Lusis,A. J. (1994) Arterio. Thromb. Vasc. Biol. 14, 1480–1497.

    CAS  Google Scholar 

  16. Grines, C. L., Watkins, M. W., Helmer, G., Penny, W., Brinker, J., Marmur, J. D., West, A., Rade, J. J., Marrott, P., Hammond, H. K. and Engler, R. L. (2002)Circulation 105, 1291–1297.

    PubMed  CAS  Google Scholar 

  17. Chang, M. W., Barr, E., Seltzer, J., Jiang, Y.-Q., Nabel, G. J., Nabel, E. G., Parmacek, M.S. and Leiden, J. M. (1995)Science 267, 518–522.

    PubMed  CAS  Google Scholar 

  18. Yang, Z.-Y., Simari, R. D., Perkins, N. D., San, H., Gordon, D., Nabel, G. J. and Nabel,E. G. (1996) Proc. Nat. Acad. Sci. U.S.A. 93, 7905–7910.

    CAS  Google Scholar 

  19. George, S. J., Johnson, J. L., Angelini, G. D., Newby, A. C. and Baker, A. H. (1998)Hum. Gene Ther. 9, 867–877.

    PubMed  CAS  Google Scholar 

  20. George, S. J., Baker, A. H., Angelini, G. D. and Newby, A. C. (1998)Gene Ther. 5,1552–1560.

    PubMed  CAS  Google Scholar 

  21. George, S. J., Angelini, G. D., Capogrossi, M. C. and Baker, A. H. (2001)Gene Ther. 8,668–76.

    PubMed  CAS  Google Scholar 

  22. Baker, A. H., Zaltsman, A. B., George, S. J. and Newby, A. C. (1998)J. Clin. Invest.101, 1478–1487.

    PubMed  CAS  Google Scholar 

  23. George, S. J., Lloyd, C. T., Angelini, G. D., Newby, A. C. and Baker, A. H. (1999)Circulation 101, 296–304.

    Google Scholar 

  24. Mann, M. J., Whittemore, A. D., Donaldson, M. C., Belkin, M., Conte, M. S., Polak, J. F., Orav, E. J., Ehsan, A., Dell’Acqua, G. D. and Dzau, V. (1999)The Lancet 354, 1493–1498.

    CAS  Google Scholar 

  25. Mann, M. J. and Dzau, V. J. (2000)J. Clin. Invest. 106, 1071–5.

    PubMed  CAS  Google Scholar 

  26. Campeau, L., Enjalbert, M., Lesperance, J., Vaislic, C., Grondin, C. M. and Bourassa, M.G. (1983)Circulation 68 (suppl. II), 1–7.

    Google Scholar 

  27. Wang, C., Chao, L. and Chao, J. (1995)J. Clin. Invest. 95, 1710–1716.

    PubMed  CAS  Google Scholar 

  28. Lin, K., Chao, L. and Chao, J. (1997)Hypertension 30, 307–313.

    PubMed  CAS  Google Scholar 

  29. Mohuczy, D., Gelband, C. H. and Phillips, I. M. (1999)Hypertension 33 (part II), 354–359.

    PubMed  CAS  Google Scholar 

  30. Zoldhelyi, P., McNatt, J., Xu, X.-M., Loose-Mitchell, D., Meidell, R. S., Clubb, F. J.,Buja, M., Willerson, J. T. and Wu, K. K. (1996)Circulation 93, 10–17.

    PubMed  CAS  Google Scholar 

  31. Numaguchi, Y., Naruse, K., Harada, M., Osanai, H., Mokuno, S., Murase, K., Matsui, H., Toki, Y., Ito, T., Okumura, K. and Hayakawa, T. (1999) Arterio. Thromb. Vasc. Biol. 19, 727–733.

    CAS  Google Scholar 

  32. Vassalli, G. and Dichek, D. A. (1998) in Principles of Molecular Medicine (Jameson, J.L., ed.), pp. 161–168, Humana Press Inc., Totowa, NJ.

    Google Scholar 

  33. Baker, A., Mehta, D., George, S. J. and Angelini, G. D. (1997)Cardiovasc.Res. 35, 442–450.

    PubMed  CAS  Google Scholar 

  34. Francis, S. C., Raizada, M. K., Mangi, A. A., Melo, L. G., Dzau, V. J., Vale, P. R., Isner, J. M., Losordo, D. W., Chao, J., Katovich, M. J. and Berecek, K. H. (2001)Physiol. Genomics 7, 79–94.

    PubMed  CAS  Google Scholar 

  35. Khurana, R., Martin, J. F. and Zachary, I. (2001)Hypertension 38, 1210–1216.

    PubMed  CAS  Google Scholar 

  36. Reissen, R., Rahimizadeh, H., Blessing, E., Takeshita, S., Barry, J. J. and Isner, J. M.(1993)Hum. Gene Ther. 4, 749–758.

    Google Scholar 

  37. Nabel, E. G., Yang, Z., Liptay, S., San, H., Gordon, D., Haudenschild, C. C. and Nabel,G. J. (1993)J. Clin. Invest. 91, 1822–1829.

    PubMed  CAS  Google Scholar 

  38. Nabel, E. G., Yang, Z., Plautz, G., Forough, R., Zhan, X., Haudenshild, C. C., Maciag, T.and Nabel, G. J. (1993)Nature 362, 844–846.

    PubMed  CAS  Google Scholar 

  39. Nabel, E. G., Shum, L., Pompili, V. J., Yang, Z. Y., San, H., Shu, H. B., Liptay, S., Gordon, D., Derynck, R. and Nabel, G. J. (1993) Proc. Nat. Acad. Sci. U.S.A. 90, 10759–10763.

    CAS  Google Scholar 

  40. Takeshita, S., Tsurumi, Y., Couffinahl, T., Asahara, T., Bauters, C., Symes, J., Ferrara,N. and Isner, J. M. (1996)Lab. Invest. 75, 487–501.

    PubMed  CAS  Google Scholar 

  41. Baumgartner, I., Pieczek, A., Manor, O., Blair, R., Kearney, M., Walsh, K. and Isner, J.M. (1998)Circulation 97, 1114–1123

    PubMed  CAS  Google Scholar 

  42. Losordo, D. W., Vale, P. R., Symes, J. F., Dunnington, C. H., Esakof, D. D., Maysky, N.,Ashare, A. B., Lathi, K. and Isner, J. M. (1998)Circulation 98, 2800–2094.

    PubMed  CAS  Google Scholar 

  43. Vale, P. R., Losordo, D. W., Milliken, C. E., Maysky, M., Esakof, D. D., Symes, J. F. and Isner, J. M. (2000)Circulation 102, 965–974.

    PubMed  CAS  Google Scholar 

  44. Vale, P. R., Losordo, D. W., Milliken, C. E., McDonald, M. C., Gravelin, L. M., Curry, C. M., Esakof, D. D., Maysky, M., Symes, J. F. and Isner, J. M. (2001)Circulation 103, 2138–2143.

    PubMed  CAS  Google Scholar 

  45. Lee, R. J., Springer, M. L., Blanco-Bose, W. E., Shaw, R., Ursell, P. C. and Blau, H. M.(2000)Circulation 102, 898–901.

    PubMed  CAS  Google Scholar 

  46. Lawrie, A., Brisken, A. F., Francis, S. E., Tayler, D. I., Chamberlain, J., Crossman, D. C.,Cumberland, D. C. and Newman, C. M. (1999)Circulation 99, 2617–2620.

    PubMed  CAS  Google Scholar 

  47. Lawrie, A., Brisken, A. F., Francis, S. E., Cumberland, D. C., Crossman, D. C. and Newman, C. M. (2000)Gene Ther. 7, 2023–2027.

    PubMed  CAS  Google Scholar 

  48. Taniyama, Y., Tachibana, K., Hiraoka, K., Namba, T., Yamasaki, K., Hashiya, N., Aoki, M., Ogihara, T., Yasufumi, K. and Morishita, R. (2002)Circulation 105, 1233–1239.

    PubMed  CAS  Google Scholar 

  49. Feigner, P. L. and Ringold, G. M. (1989)Nature 337, 387–338.

    Google Scholar 

  50. Stephan, D. J., Yang, Z. Y., San, H., Simari, R. D., Wheeler, C. J., Felgrer, P. L., Gordon,D., Nabel, G. J. and Nabel, E. G. (1996)Hum. Gene Ther. 7, 1803–1812.

    PubMed  CAS  Google Scholar 

  51. Muller, D. W., Gordon, D., San, H., Yang, Z., Pompili, V. J., Nabel, G. J. and Nabel, E.G. (1994)Circ. Res. 75, 1039–1049.

    PubMed  CAS  Google Scholar 

  52. Tanner, F. C., Carr, D. P., Nabel, G. J. and Nabel, E. G. (1997)Cardiovasc. Res. 35, 522–528.

    PubMed  CAS  Google Scholar 

  53. Leclerc, G., Gal, D., Takeshita, S., Nikol, S., Weir, L. and Isner, J. M. (1992)J. Clin.Invest. 90, 936–944.

    PubMed  CAS  Google Scholar 

  54. Nabel, E. G., Plautz, G. and Nabel, G. J. (1990)Science 249, 1285–1288.

    PubMed  CAS  Google Scholar 

  55. Plautz, G., Nabel, E. G. and Nabel, G. J. (1991)Circulation 83, 578–583.

    PubMed  CAS  Google Scholar 

  56. Forough, R., Koyama, N., Hasentab, D., Lea, H., Clowes, M., Nikkari, S. T. and Clowes,A. W. (1996)Circ. Res. 79, 812–820.

    PubMed  CAS  Google Scholar 

  57. Cioffi, L., Sturtz, F. G., Wittmer, S., Barut, B., Smith-Gbur, J., Moore, V., Zupanic, T., Gilligan, B., Auerbach, R., Gomez, F., Chauvin, F., Antczak, M., Platika, D. and Snodgrass, H. R. (1999)Gene Ther. 6, 1153–1159.

    PubMed  CAS  Google Scholar 

  58. Anderson, W. F. (1984)Science 226, 401–409.

    PubMed  CAS  Google Scholar 

  59. Eglitis, M. A., Kantoff, P. W., Gilboa, E. and Anderson, W. F. (1985)Science 230, 1395–1398.

    PubMed  CAS  Google Scholar 

  60. Friedman, T. (1989)Science 244, 1275–1281.

    Google Scholar 

  61. Hock, R. A. and Miller, A. D. (1986)Nature 320, 275–277.

    PubMed  CAS  Google Scholar 

  62. Miller, D. G., Adam, M. A. and Miller, A. D. (1990)Mol. Cell Biol. 10, 4239–4242.

    PubMed  CAS  Google Scholar 

  63. Herzog, R. W., Yang, E. Y., Couto, L. B., Hagstrom, J. N., Elwell, D., Fields, P. A., Burton, M., Bellinger, D. A., Read, M. S., Brinkhous, K. M., Podsakoff, G. M., Nichols, T. C., Kurtzman, G. J. and High, K. A. (1999)Nature Med. 5, 56–63.

    PubMed  CAS  Google Scholar 

  64. Snyder, R. O., Miao, C., Meuse, L., Tubb, J., Donahue, A. R., Lin, H.-F., Stafford, D. W., Patel, S., Thompson, A. R., Nichols, T., Read, M. S., Bellinger, D. A., Brinkhous, K. M. and Kay, M. A. (1999)Nature Med. 5, 64–70.

    PubMed  CAS  Google Scholar 

  65. Lynch, C. M., Hara, P. S., Leonard, J. C., Koudy Williams, J., Dean, R. H. and Geary, R.L. (1997)Circ. Res. 80, 497–505.

    PubMed  CAS  Google Scholar 

  66. Maeda, Y., Ikeda, U., Ogasawara, Y., Urabe, M., Takizawa, T., Saito, T., Colosi, T.,Kurtzman, G., Shimada, K. and Ozawa, K. (1997)Cardiovasc. Res. 35, 514–521.

    PubMed  CAS  Google Scholar 

  67. Richter, M., Iwata, A., Nyhuis, J., Nitta, Y., Miller, A. D., Halbert, C. L. and Allen, M. D. (2000)Physiol. Genomics 2, 117–127.

    PubMed  CAS  Google Scholar 

  68. Su, H., Lu, R. and Kan, Y. W. (2000) Proc. Nat. Acad. Sci. U.S.A. 97, 13801–13806.

    CAS  Google Scholar 

  69. Shimpo, M., Ikeda, U., Maeda, Y., Takahashi, M., Miyashita, H., Mizukami, H., Urabe, M., Kume, A., Takizawa, T., Shibuya, M., Ozawa, K. and Shimada, K. (2002)Cardiovasc. Res. 53, 993–1001.

    PubMed  CAS  Google Scholar 

  70. Kawada, T., Nakazawa, M., Nakauchi, S., Yamazaki, K., Shimamoto, R., Urabe, M., Nakata, J., Hemmi, C., Masui, F., Nakajima, T., Suzuki, J.-I., Monahan, J., Sato, H., Masaki, T., Ozawa, K. and Toyo-oka, T. (2002) Proc. Nat. Acad. Sci. U.S.A. 99, 901–906.

    CAS  Google Scholar 

  71. Melo, L. G., Agrawal, R., Zhang, L., Rezvani, M., Mangi, A. A., Ehsan, A., Griese, D. P., Dell’Acqua, G., Mann, M. J., Oyama, J., Yet, S.-F., Layne, M. D., Perrella, M. A. and Dzau, V. J. (2002)Circulation 105, 602–607.

    PubMed  CAS  Google Scholar 

  72. Merrick, A. F., Shewring, L. D., Sawyer, G. J., Gustafsson, K. T. and Fabre, J. W. (1996)Transplantation 62, 1085–1089.

    PubMed  CAS  Google Scholar 

  73. Jaffe, H. A., Danel, C., Cid, M. C., Kleinman, H. K., StratfordPavirani, A., Le Cocq, J.-P. and Crystal, R. G. (1992)Proc. Nat. Acad.72 6482–6486.

    Google Scholar 

  74. Jones, M., Yamada, I. and Crystal, R. G. (1993)Circ. Res. 72(5), 1132–1138.

    PubMed  Google Scholar 

  75. Channon, K. M., Qian, H., Youngblood, S. A., Olmez, E., Shetty, G. A., Neplioueva, V.,Blazing, M. A. and George, S.E. (1998)Circ. Res. 82, 1253–1262.

    PubMed  CAS  Google Scholar 

  76. Yang, Y., Nunes, F. A., Berencsi, K., Furth, E. E., Gönczol, E. and Wilson, J. M. (1994)Proc. Nat. Acad. Sci. U.S.A. 91, 4407–4411.

    CAS  Google Scholar 

  77. Yang, Y., Li, Q., Ertl, H. C. J., and Wilson, J. M. (1995)J. Virol. 69, 2004–2015.

    PubMed  CAS  Google Scholar 

  78. Yang, Y., Su, Q. and Wilson, J. M. (1996)J. Virol. 70, 7209–7212.

    PubMed  CAS  Google Scholar 

  79. Hiltunen, M. O., Turunen, M. P., Turunen, A.-M., Rissanen, T. T., Laitinen, M., Kosma,V.-M. and Yla-Herttuala, S. (2000)FASEB J. 14, 2230–2236.

    PubMed  CAS  Google Scholar 

  80. Gladson, C. L. and Cheresh, D. A. (1994) in Integrins: the Biological Problems (Takada,Y., ed.), pp. 83–99, CRC Press, Boca Raton, FL.

    Google Scholar 

  81. Pasqualini, R., Koivunen, E. and Ruoslahti, E. (1995)J. Cell Biol. 130, 1189–1196.

    PubMed  CAS  Google Scholar 

  82. Wilson, D. R. and Finlay, B. B. (1998)Canad. J. Microbiol. 44, 313–329.

    CAS  Google Scholar 

  83. Smith, G. P. (1985)Science 228, 1315–1317.

    PubMed  CAS  Google Scholar 

  84. Cwirla, S. E., Peters, E. A., Barrett, R. W. and Dower, W. J. (1990)Proc. Nat. Acad. Sci.U.S.A. 87, 6378–6382.

    CAS  Google Scholar 

  85. Devlin, J. J., Panganiban, L. C. and Devlin, P. E. (1990)Science 249, 404–406.

    PubMed  CAS  Google Scholar 

  86. Scott, J. K. and Smith, G. P. (1990)Science 228, 1315–1317.

    Google Scholar 

  87. Smith, G. P. (1993)Gene 128, 1–2.

    Google Scholar 

  88. Luzzago, A., Felici, F., Tramontano, A., Pessi, A. and Cortese, R. (1993)Gene 128, 51–57.

    PubMed  CAS  Google Scholar 

  89. McLafferty, M. A., Kent, R. B., Ladner, R. C. and Markland, W. (1993)Gene 128, 29–36.

    PubMed  CAS  Google Scholar 

  90. Wrighton, N. C., Farrell, F. X., Chang, R., Kashyap, A. K., Barbone, F. P., Mulcahy, L. S., Johnson, D. L., Barrett, R. W., Jolliffe, L. K. and Dower, W. J. (1996)Science 273, 458–464.

    PubMed  CAS  Google Scholar 

  91. Pasqualini, R. and Ruoslahti, E. (1996)Nature 380, 364–366.

    PubMed  CAS  Google Scholar 

  92. Pasqualini, R., Koivunen, E. and Ruoslahti, E. (1997)Nature Biotechnol. 15, 542–546.

    CAS  Google Scholar 

  93. Rajotte, D., Arap, W., Hagedorn, M., Koivunen, E., Pasqualini, R. and Ruoslahti, E.(1998)J. Clin. Invest. 102, 430–437.

    PubMed  CAS  Google Scholar 

  94. Arap, W., Pasqualini, R. and Ruoslahti, E. (1998)Science 279, 377–380.

    PubMed  CAS  Google Scholar 

  95. Burg, M. A., Pasqualini, R., Arap, W., Ruoslahti, E. and Stallcup, W. B. (1999)Cancer Res. 59, 2869–2874.

    PubMed  CAS  Google Scholar 

  96. Ruoslahti, E. and Rajotte, D. (2000)Annu. Rev. Immunol. 18, 813–827.

    PubMed  CAS  Google Scholar 

  97. Essler, M. and Ruoslahti, E. (2002) Proc. Nat. Acad. Sci. U.S.A. 99, 2252–2257.

    CAS  Google Scholar 

  98. Arap, W., Haedicke, W., Bernascni, M., Kain, R., Rajotte, D., Krajewski, S., Ellerby, H. M., Bredesen, D. E., Pasqualini, R. and Ruoslahti, E. (2002) Proc. Nat. Acad. Sci. U.S.A. 99,1527–1531.

    CAS  Google Scholar 

  99. Arap, W., Kolonin, M. G., Trepel, M., Landenranta, J., Cardo-Vila, M., Giordano, R. J., Mintz, P. J., Ardelt, P. U., Yao, V. J., Vidal, C. I., Chen, L., Flamm, A., Valtanen, H., Weavind, L. M., Hicks, M. E., Pollock, R. E., Botz, G. H., Bucana, C. D., Koivunen, E., Cahill, D., Troncoso, P., Baggerly, K. A., Pentz, R. D., Do, K.-A., Logothetis, C. J. and Pasqualini, R. (2002)Nature Med. 8, 121–127.

    PubMed  CAS  Google Scholar 

  100. Michon, I. N., Hauer, A. D., von der Thüsen, J. H., Molenaar, T. J. M., van Berke], T. J.C., Biessen, E. A. L. and Kuiper, J. (2002) Biochim. Biophys. Acta 1591, 87–97.

    CAS  Google Scholar 

  101. Hermann, A., Pieper, M. and Schrader, J. (1999) Biochim. Biophys. Acta 1472, 529–536.

    Google Scholar 

  102. Houston, P., Goodman, J., Lewis, A., Campbell, C. J. and Braddock, M. (2001) FEBS Letts. 246–351 5.

    Google Scholar 

  103. Nicklin, S. A., White, S. J., Watkins, S. J., Hawkins, R. E. and Baker, A. H. (2000)Circulation 102, 231–237.

    PubMed  CAS  Google Scholar 

  104. Nicklin, S. A., Buening, H., Dishart, K. L., de Alwis, M., Girod, A., Hacker, U., Thrasher, A. J., Ali, R. R., Hallek, M. and Baker, A. H. (2001)Mol. Ther. 4, 174–181.

    PubMed  CAS  Google Scholar 

  105. Nicklin, S. A., Von Seggern, D. J., Work, L. M., Pek, D. C. K., Dominiczak, A. F., Nemerow, G. R. and Baker, A. H. (2001)Mol. Ther. 4, 534–542.

    PubMed  CAS  Google Scholar 

  106. Xia, H., Anderson, B., Mao, Q. and Davidson, B. L. (2000)J. Virol. 74, 11359–11366.

    PubMed  CAS  Google Scholar 

  107. Bergelson, J. M., Cunningham, J. A., Droguett, G., Kurt-Jones, E. A., Krithivas, A., Hong, J. S., Horwitz, M. S., Crowell, R. L. and Finberg, R. W. (1997)Science 275, 1320–1323.

    PubMed  CAS  Google Scholar 

  108. Tomko, R. P., Xu, R. and Philipson, L. (1997) Proc. Nat. Acad. Sci. U.S.A. 94, 3352–3356.

    CAS  Google Scholar 

  109. Wickham, T. J., Mathias, P., Cheresh, D. A. and Nemerow, G. R. (1993)Cell 73, 309–319.

    PubMed  CAS  Google Scholar 

  110. Wickham, T. J., Filardo, E. J., Cheresh, D. A. and Nemerow, G. R. (1994)J. Cell Biol.124,257–264.

    Google Scholar 

  111. Hackett, N. R., El Sawy, T., Lee, L. Y., Silva, I., O’Leary, J., Rosengart, T. K. And Crystal, R. G. (2000)Mol. Ther. 2, 649–656.

    PubMed  CAS  Google Scholar 

  112. Doukas, J., Hoganson, D.K., Ong, M., Ying, W., Lacey, D.L., Baird, A., Pierce, G.F. and Sosnowski, B.A.A. (1999)FASEB J. 13, 1459–1466.

    PubMed  CAS  Google Scholar 

  113. Wickham, T. J., Segal, D. M., Roelvink, P. W., Carrion, M. E., Lizonova, A., Lee, G. M. and Kovesdi, I. (1996)J. Virol. 70(10), 6831–6838.

    PubMed  CAS  Google Scholar 

  114. Watkins, S. J., Mesyanzhinov, V., Kurochkina, L. P. and Hawkins, R. E. (1997)Gene Ther. 4, 1004–1012.

    PubMed  CAS  Google Scholar 

  115. Harari, O. A., Wickham, T. J., Stocker, C. J., Kovesdi, I., Segal, D. M., Huehns, T. Y., Sarraf, C. and Haskard, D. O. (1999)Gene Ther. 6, 801–807.

    PubMed  CAS  Google Scholar 

  116. Nettelbeck, D. M., Miller, D. W., Jerome, V., Zuzarte, M., Watkins, S. J., Hawkins, R.E., Muller, R. and Kontermann, R. E. (2001)Mol. Ther. 3, 882–891.

    PubMed  CAS  Google Scholar 

  117. Trepel, M., Grifman, M., Weitzman, M. D. and Pasqualini, R. (2000)Hum. Gene Ther. 11,1971–1981.

    PubMed  CAS  Google Scholar 

  118. Trepel, M., Arap, W. and Pasqualini, R. (2000)Gene Ther. 7, 2059–60.

    PubMed  CAS  Google Scholar 

  119. Reynolds, P. N., Zinn, K. R., Gavrilyuk, V. D., Balyasnikova, I. V., Rogers, B. E., Buchsbaum, D. J., Wang, M. H., Miletich, D. J., Grizzle, W. E., Douglas, J. T., Danilov, S. M. and Curiel, D. T. (2000)Mol. Ther. 2, 562–578.

    PubMed  CAS  Google Scholar 

  120. Caldwell, P. R., Seegal, B. C., Hsu, K. C., Das, M. and Soffer, R. L. (1976)Science 191,1050–1051.

    PubMed  CAS  Google Scholar 

  121. Schuster, D. P., Crouch, E. C., Parks, W. C., Johnson, T. and Botney, M. D. (1996)Amer. J. Resp. Crit. Care Med. 154, 1087–1091.

    CAS  Google Scholar 

  122. Nicklin, S. A., Reynolds, P. N., Brosnan, M. J., White, S. J., Curiel, D. T., Dominiczak,A. F. and Baker, A. H. (2001)Hypertension 38, 65–70.

    PubMed  CAS  Google Scholar 

  123. Reynolds, P. N., Nicklin, S. A., Kaliberova, L., Boatman, B. G., Grizzle, W. E., Balyasnikova, I., Baker, A. H., Danilov, S. M. and Curiel, D. T. (2001)Nature Biotechnol. 19, 838–842.

    CAS  Google Scholar 

  124. Krasnykh, V. N., Mikheeva, G. V., Douglas, J. T. and Curiel, D. T. (1996)J. Virol. 70,6839–6846.

    PubMed  CAS  Google Scholar 

  125. Su, E. J., Stevenson, S. C., Rollence, M., Marshall-Neff, J. and Liau, G. (2001)J. Vast.Res. 38, 471–478.

    CAS  Google Scholar 

  126. Havenga, M. J. E., Lemckert, A. A. C., Grimbergen, J. M., Vogels, R., Huisman, L. G.M., Valerio, D., Bout, A. and Quax, P. H. A. (2001)J. Virol. 75, 3335–3342.

    PubMed  CAS  Google Scholar 

  127. Chillon, M., Bosch, A., Zabner, J., Law, L., Armentano, D., Welsh, M. J. and Davidson, B. L. (1999)J. Virol. 73, 2537–2540.

    PubMed  CAS  Google Scholar 

  128. Xia, D., Henry, L. J., Gerard, R. D. and Deisenhofer, J. (1994)Structure 2, 1259–1270.

    PubMed  CAS  Google Scholar 

  129. Kirby, I., Davison, E., Beavil, A. J., Soh, C. P. C., Wickham, T. J., Roelvink, P. W.,Kovesdi, L., Sutton, B. J. and Santis, G. (1999)J. Virol. 73, 9508–9514.

    PubMed  CAS  Google Scholar 

  130. Kirby, I., Davidson, E., Beavil, A. J., Soh, C. P. C., Wickham, T. J., Roelvink, P. W.,Kovesdi, I., Sutton, B. J. and Santis, G. (2000)J. Virol. 74, 2804–2813.

    PubMed  CAS  Google Scholar 

  131. Roelvink, P. W., Lee, G. M., Einfeld, D. A., Kovesdi, I. and Wickham, T. J. (1999)Science 286, 1568–1571.

    PubMed  CAS  Google Scholar 

  132. Micheal, S. I., Hong, J. S., Curiel, D. T. and Engler, J. A. (1995) Gene Ther. 2, 660–668.

    Google Scholar 

  133. Wickham, T. J., Roelvink, P. W., Brough, D. E. and Kovesdi, L. (1996)Nature Biotechnol. 14, 1570–1573.

    CAS  Google Scholar 

  134. Wickham, T. J., Tzeng, E., Shears II, L. L., Roelvink, P. W., Li, Y., Lee, G. M., Brough, D. E., Lizonova, A. and Kovesdi, I. (1997)J. Virol. 71, 8221–8229.

    PubMed  CAS  Google Scholar 

  135. Krasnykh, V., Dmitriev, I., Mikheeva, G., Miller, R., Belousova, N. and Curiel, D. T.(1998)J. Virol. 72, 1844–1852.

    PubMed  CAS  Google Scholar 

  136. Dmitriev, I., Krasnykh, V., Miller, C. R., Wang, M., Kashentseva, E., Mikheeva, G.,Belousova, N. and Curiel, D. T. (1998)J. Virol. 72, 9706–9713.

    PubMed  CAS  Google Scholar 

  137. Cripe, T. P., Dunphy, E. J., Holub, A. D., Saini, A., Vasi, N. H., Mahller, Y. Y., Collins, M. H., Snyder, J. D., Krasnykh, V., Curiel, D. T., Wickham, T. J., DeGregori, J., Bergelson, J. M. and Currier, M. A. (2001)Cancer Res. 61, 2953–2960.

    PubMed  CAS  Google Scholar 

  138. Okada, N., Tsukada, Y., Nakagawa, S., Mizuguchi, H., Mori, K., Saito, T., Fujita, T., Yamamoto, A., Hayakawa, T. and Mayumi, T. (2001) Biochem. Biophys. Res. Commun. 282,173–179.

    CAS  Google Scholar 

  139. Garcia-Castro, J., Segovia, J. C., Garcia-Sanchez, F., Lillo, R., Gomez-Navarro, J., Curiel, D. T. and Bueren, J. A. (2001)Mol. Ther. 3, 70–77.

    PubMed  CAS  Google Scholar 

  140. Wesseling, J. G., Bosma, P. J., Krasnykh, V., Kashentseva, E. A., Blackwell, J. L., Reynolds, P. N., Li, H., Parameshwar, M., Vickers, S. M., Jaffee, E. M., Huibregtse, K., Curiel, D. T. and Dmitriev, I. (2001)Gene Ther. 8, 969–976.

    PubMed  CAS  Google Scholar 

  141. Kanerva, A., Wang, M., Bauerschmitz, G. J., Lam, J. T., Desmond, R. A., Bhoola, S. M., Barnes, M. N., Alvarez, R. D., Siegal, G. P., Curiel, D. T. and Hemminki, A. (2002)Mol. Ther. 5, 695–704.

    PubMed  CAS  Google Scholar 

  142. Nakamura, T., Sato, K. and Hamada, H. (2002)Hum. Gene Ther. 13, 613–626.

    PubMed  CAS  Google Scholar 

  143. Hay, C. M., De Leon, H., Jafari, J. D., Jakubczak, J. L., Mech, C. A., Hallenbeck, P. L., Powell, S. K., Liau, G. and Stevenson, S. C. (2001)J. Vase. Res. 38, 315–323.

    CAS  Google Scholar 

  144. Vigne, E., Mahfouz, I., Dedieu, J.-F., Brie, A., Perricaudet, M. and Yeh, P. (1999)J. Virol. 73, 5156–5161.

    PubMed  CAS  Google Scholar 

  145. Jakubczak, J. L., Rollence, M. L., Stewart, D. A., Jafari, J. D., Von Seggern, D. J., Nemerow, G. R., Stevenson, S. C. and Hallenbeck, P. L. (2001)J. Virol. 75, 2972–2981.

    PubMed  CAS  Google Scholar 

  146. Leissner, P., Legrand, V., Schlesinger, Y., Hadji, D. A., van Raaij, M., Cusack, S., Pavirani, A. and Mehtali, M. (2001)Gene Ther. 8, 49–57.

    PubMed  CAS  Google Scholar 

  147. Alemany, R. and Curiel, D. T. (2001)Gene Ther. 8, 1347–1353.

    PubMed  CAS  Google Scholar 

  148. Einfeld, D. A., Schroeder, R., Roelvink, P. W., Lizonova, A., King, C. R., Kovesdi, I. and Wickham, T. J. (2001)J. Virol. 75, 11284–11291.

    PubMed  CAS  Google Scholar 

  149. Reynolds, P. N., Dmitriev, I. and Curiel, D. T. (1999)Gene Ther. 6, 1336–1339.

    PubMed  CAS  Google Scholar 

  150. Smith, T. A., Marshall-Neff, J., Idamakanti, N., Rolence, M. L., Kylefjord, H., Mulgrew, K., Theurer, M., Dinges, L., Kaleko, M. and Stevenson, S. C. (2002)Mol. Ther. 5, S208.

    Google Scholar 

  151. Halbert, C. L., Allen, J. M. and Miller, A. D. (2001)J. Virol. 75, 6615–6624.

    PubMed  CAS  Google Scholar 

  152. Kaludov, N., Brown, K. E., Walters, R. W., Zabner, J. and Chiorini, J. A. (2001)J. Virol.75,6884–6893.

    PubMed  CAS  Google Scholar 

  153. Hildinger, M., Auricchio, A., Gao, G., Wang, L., Chirmule, N. and Wilson, J. M. (2001)J. Virol. 75, 6199–6203.

    PubMed  CAS  Google Scholar 

  154. Auricchio, A., Kobinger, G., Anand, V., Hildinger, M., O’Connor, E., Maguire, A. M.,Wilson, J. M. and Bennett, J. (2001)Hum. Mol. Gen. 10, 3075–3081.

    PubMed  CAS  Google Scholar 

  155. Davidson, B. L., Stein, C. S., Heth, J. A., Martins, I., Kotin, R. M., Derksen, T. A., Zabner, J., Ghodis, A. and Chiorini, J. A. (2000) Proc. Nat. Acad. Sci. U.S.A. 97, 3428–3432.

    CAS  Google Scholar 

  156. Yan, Z., Zak, R., Luxton, G. W. G., Ritchie, T. C., Bantel-Schaal, U. and Engelhardt, J.F. (2002)J. Virol. 76, 2043–2053.

    PubMed  CAS  Google Scholar 

  157. Gao, G.-P., Alvira, M. R., Calcedo, R., Johnston, J. and Wilson, J. M. (2002) Proc. Nat. Acad. Sci. U.S.A. 99, 11854–11859.

    CAS  Google Scholar 

  158. Summerford, C. and Samulski, R. J. (1998)J. Virol. 72, 1438–1445.

    PubMed  CAS  Google Scholar 

  159. Qing, K., Mah, C., Hansen, J., Zhou, S., Dwarki, V. and Srivastava, A. (1999)Nature Med. 5, 71–77.

    PubMed  CAS  Google Scholar 

  160. Summerford, C., Bartlett, J. S. and Samulski, R.-J. (1999)Nat. Med. 5, 78–82.

    PubMed  CAS  Google Scholar 

  161. Passini, M. A., and Wolfe, J. H. (2001)J. Virol. 75, 12382–12392.

    PubMed  CAS  Google Scholar 

  162. Kessler, P. D., Podsakoff, G. M., Chen, X., McQuiston, S. A., Colosi, P. C., Matelis, L. A., Kurtzman, G. J. and Byrne, B. J. (1996) Proc. Nat. Acad. Sci. U.S.A. 93, 14082–14087.

    CAS  Google Scholar 

  163. Koeberl, D. D., Alexander, I. E., Halbert, C. L., Russell, D. W. and Miller, A. D. (1997) Proc. Nat. Acad. Sci. U.S.A. 94, 1426–1431.

    CAS  Google Scholar 

  164. Ali, R. R., Reichel, M. B., Thrasher, A. J., Levinsky, R. J., Kinnon, C., Kanuga, N., Hunt,D. M. and Bhattacharya, S. S. (1996)Hum. Mol. Gen. 5, 591–594.

    PubMed  CAS  Google Scholar 

  165. Fisher, K. J., Jooss, K., Alston, J., Yang, Y., Ehlen Haecker, S., High, K., Pathak, R.,Raper, S. E. and Wilson, J. M. (1997)Nature Med. 3, 306–312.

    PubMed  CAS  Google Scholar 

  166. McCown, T. J., Xiao, X., Li, J., Breese, G. R. and Samulski, R. J. (1996)Brain Res. 713,99–107.

    PubMed  CAS  Google Scholar 

  167. Duan, D., Yue, Y., Yan, Z. and Engelhardt, J. F. (2000)J. Clin. Invest. 105, 1573–1587.

    PubMed  CAS  Google Scholar 

  168. Hansen, J., Qing, K., Kwon, H.-J., Mah, C. and Srivastava, A. (2000)J. Virol. 74, 992–996.

    Google Scholar 

  169. Hansen, J., Qing, K. and Srivastava, A. (2001)J. Virol. 75, 4080–4090.

    PubMed  CAS  Google Scholar 

  170. Bartlett, J. S., Kleinschmidt, J., Boucher, R. C. and Samulski, R. J. (1999)Nature Biotechnol. 17, 181–186.

    CAS  Google Scholar 

  171. Ried, M. U., Girod, A., Leike, K., Buning, H. and Hallek, M. (2002)J. Virol. 76, 4559–4566.

    Google Scholar 

  172. Girod, A., Ried, M., Wobus, C., Lahm, H., Leike, K., Kleinschmidt, J., Deleage, G. And Hallek, M. (1999)Nature Med. 5, 1052–1056.

    PubMed  CAS  Google Scholar 

  173. Grifman, M., Trepel, M., Speece, P., Gilbert, L. B., Arap, W., Pasqualini, R. And Weitzman, M. D. (2001)Mol. Ther. 3, 964–975.

    PubMed  CAS  Google Scholar 

  174. Shi, W., Arnold, G. S. and Bartlett, J. S. (2001)Hum. Gene Ther. 12, 1697–1711.

    PubMed  CAS  Google Scholar 

  175. Yang, Q. C., Mamounas, M., Yu, G., Kennedy, S., Leaker, B., Merson, J., WongStaal, F.,Yu, M. and Barber, J. R. (1998)Hum. Gene Ther. 9, 1929–1937.

    PubMed  CAS  Google Scholar 

  176. Xie, Q., Bu, W., Bhatia, S., Hare, J., Somasundaram, T., Azzi, A. and Chapman, M. S.(2002) Proc. Nat. Acad. Sci. U.S.A. 99, 10405–10410.

    CAS  Google Scholar 

  177. Tsao, J., Chapman, M. S., Agbandje, M., Keller, W., Smith, K., Wu, H., Luo, M., Smith,T. J., Rossmann, M. G. and Compans, R. W. (1991)Science 251, 1456–1464.

    PubMed  CAS  Google Scholar 

  178. Wistuba, A., Kern, A., Weger, S., Grmm, D. and Kleinschmidt, J. A. (1997)J. Virol. 71, 1929–1937.

    Google Scholar 

  179. Aumailley, M., Gerl, M., Sonnenberg, A., Deutzmann, R. and Timpl, R. (1990)FEBS Letts. 262, 82–86.

    CAS  Google Scholar 

  180. Wistuba, A., Weger, S., Kern, A. and Kleinschmidt, J. (1995)J. Virol. 69, 5311–5319.

    PubMed  CAS  Google Scholar 

  181. Bayer, N., Schober, D., Prchla, E., Murphy, R. F., Blaas, D. and Fuchs, R. (1998)J.Virol. 72, 9645–9655.

    PubMed  CAS  Google Scholar 

  182. Douar, A.-M., Poulard, K., Stockholm, D. and Danos, O. (2001)J. Virol. 75, 1824–1833.

    PubMed  CAS  Google Scholar 

  183. Wilkinson, G. W. G. and Akrigg, A. (1992)Nucl. Acids Res. 20, 2233–2239.

    PubMed  CAS  Google Scholar 

  184. Boshart, M., Weber, F., Jahn, G., Dorsch-Häsler, K., Fleckenstein, B. and Schaffner, W.(1985)Cell 41, 521–530.

    PubMed  CAS  Google Scholar 

  185. Gorman, C. M., Merlino, G. T., Willingham, M. C., Pastan, I. and Howard, B. H. (1982) Proc. Nat. Acad. Sci. U.S.A. 79, 6777–6781.

    CAS  Google Scholar 

  186. Shi, Q., Wang, Y. and Worton, R. (1997)Hum. Gene Ther. 8, 403–410.

    PubMed  CAS  Google Scholar 

  187. Addison, C. L., Hitt, M., Kunsken, D. and Graham, F. L. (1997)J. Gen. Virol. 78, 1653–1661.

    PubMed  CAS  Google Scholar 

  188. Weiler-Guettler, H., Aird, W. C., Husain, M., Rayburn, H. and Rosenberg, R. D. (1996)Circ. Res. 78, 180–187.

    PubMed  CAS  Google Scholar 

  189. Aird, W. C., Jahroudi, N., Weiler-Guettler, H., Rayburn, H. B. and Rosenberg, R. D. (1995) Proc. Nat. Acad. Sci. U.S.A. 92, 4567–4571.

    CAS  Google Scholar 

  190. Schlaeger, T. M., Bartunkova, S., Lawitts, J. A., Teichmann, G., Risau, W., Deutsch, U.and Sato, T. N. (1997)Proc. Nat. Acad. Sci. U.S.A. 94, 3058–3063.

    CAS  Google Scholar 

  191. Neish, A. S., Williams, A. J., Palmer, H. J., Whitley, M. Z. and Collins, T. (1992)J. Exp.Med. 176, 1583–1593.

    PubMed  CAS  Google Scholar 

  192. Cybulsky, M. I. and Gimbrone, M. A. J. (1991)Science 251, 788–91.

    PubMed  CAS  Google Scholar 

  193. Li, H., Cybulsky, M. I., Gimbrone, M. A. J. and Libby, P. (1993)Arterio. Thromb. Vasc.Biol. 13, 197–204.

    Google Scholar 

  194. de Fourgerolles, A.R., Stacker, S.A., Schwarting, R. and Springer, T.A. (1991)J. Exp. Med. 174, 253–267.

    Google Scholar 

  195. Cowan, P. J., Shinkel, T. A., Witwort, E. J., Barlow, H., Pearse, M. J. and D’Apice, A. J.F. (1996)Transplantation 62, 155–160.

    PubMed  CAS  Google Scholar 

  196. Cowan, P. J., Tsang, D., Pedic, C. M., Abbott, L. R., Shinkel, T. A., D’Apice, A. J. F. And Pearse, M. J. (1998)J. Biol. Chem. 273, 11737–11744.

    Google Scholar 

  197. Velasco, B., Ramirez, J. R., Relloso, M., Li, C., Kumar, S., Lopez-Bote, J. P., Perez-Barriocanal, F., Lopez-Novoa, J. M., Cowan, P. J., D’Apice, A. J. F. and Bernabeu, C. (2001)Gene Ther. 8, 897–904.

    PubMed  CAS  Google Scholar 

  198. Marietta, M. A. (1994)Cell 78, 927–930.

    CAS  Google Scholar 

  199. Griffith, O. W. and Stuehr, D. J. (1995)Annu. Rev. Physiol. 57, 707–736.

    PubMed  CAS  Google Scholar 

  200. Marsden, P. A., Schappert, K. T., Chen, H. S., Flowers, M., Sundell, C. L., Wilcox, J.,Lamas, S. and Michel, T. (1992)FEBS Letts. 307, 287–293.

    CAS  Google Scholar 

  201. Marsden, P. A., Heng, H. H. Q., Scherer, S. W., Stewart, R. J., Hall, A. V., Shi, X.-M.,Tsui, L.-C. and Schappert, K. T. (1993)J. Biol. Chem. 268, 17478–17488.

    Google Scholar 

  202. Lamas, S., Marsden, P. A., Li, G. K., Tempst, P. and Michel, T. (1992) Proc. Nat. Acad.Sci. U.S.A. 89, 6348–6352.

    CAS  Google Scholar 

  203. Nishida, K., Harrison, D. G., Navas, J. P., Fisher, A. A., Dockery, S. P., Uematsu, M., Nerem, R. M., Alexander, R. W. and Murphy, T. J. (1992)J. Clin. Invest. 90, 2092–2096.

    PubMed  CAS  Google Scholar 

  204. Piovella, F., Nialli, G., Malamani, G. D., Majolino, I., Frassoni, F., Sitar, G. M., Ruggeri,A., Dell’Orbo, C. and Ascari, E. (1977)Brit. J. Haematol. 39, 209–213.

    Google Scholar 

  205. Ferriera, V., Assouline, Z., Schwachtgen, J.-L., Bahnak, B. R., Meyer, D. and Kerbiriou-Nabias, D. (1993)Biochem. J. 293, 641–646.

    Google Scholar 

  206. Mancuso, D. J., Tuley, E. A., Westfield, L. A., Worall, N. K., Shelton-Inloes, B. B., Sorace, J. M., Alevy, Y. G. and Sadler, J. E. (1989)J. Biol. Chem. 264, 19514–19527.

    PubMed  CAS  Google Scholar 

  207. Bonthron, D. and Orkin, S. H. (1988)Eur. J. Biochem. 171, 51–57.

    PubMed  CAS  Google Scholar 

  208. Collins, C. J., Underdahl, J. P., Levene, R. B., Rayera, C. P., Morin, M. J., Dombalagian, M. J., Ricca, G., Livingston, D. M. and Lynch, D. C. (1987) Proc. Nat. Acad. Sci. U.S.A. 84,4393–4397.

    CAS  Google Scholar 

  209. Jahroudi, N. and Lynch, D. C. (1994)Mol. Cell. Biol. 14, 999–1008.

    PubMed  CAS  Google Scholar 

  210. Ozaki, K., Yoshida, T., Ide, H., Saito, I., Ikeda, Y., Sugimura, T. and Masaaki, T. (1996)Hum. Gene Ther. 7, 1483–1490.

    PubMed  CAS  Google Scholar 

  211. Aird, W. C., Edelberg, J. M., Weiler-Guettler, H., Simmons, W. W., Smith, T. W. and Rosenberg, R. D. (1997)J. Cell Biol. 138, 1117–124.

    PubMed  CAS  Google Scholar 

  212. Jahroudi, N., Ardekani, A. M. and Greenberger, J. S. (1996)Blood 88, 3801–3814.

    PubMed  CAS  Google Scholar 

  213. De Vries, C., Escobedo, J. A., Ueno, H., Houck, K., Ferrara, N. and Williams, L. T. (1992)Science 255, 989–991.

    PubMed  CAS  Google Scholar 

  214. Peters, K. G., De Vries, C. and Williams, L. T. (1993) Proc. Nat. Acad. Sci. U.S.A. 90, 8915–8919.

    CAS  Google Scholar 

  215. Morishata, K., Johnson, D. E. and Williams, L. T. (1995)J. Biol. Chem. 270, 27948–27953.

    Google Scholar 

  216. Wakija, K., Begue, A., Stehelin, D. and Shibuya, M. (1996)J. Biol. Chem. 271, 30823–30828.

    Google Scholar 

  217. Gerber, H.-P., Condorelli, F., Park, J. and Ferrara, N. (1997)J. Biol. Chem. 272, 23659–23667.

    PubMed  CAS  Google Scholar 

  218. Chen, Y.S., Hackett, S. F., Schoenfeld, C.-L., Vinores, M. A., Vinores, S. A. and Campochiaro, P. A. (1997)Brit. J. Opthalmol. 81, 919–926.

    CAS  Google Scholar 

  219. Barleon, B., Sozzani, S., Zhou, D., Weich, H. A., Mantovani, A. and Marme, D. (1996)Blood 87,3336–3343.

    PubMed  CAS  Google Scholar 

  220. Wang, H. and Keiser, J. A. (1998)Circ. Res. 83, 832–840.

    PubMed  CAS  Google Scholar 

  221. Lindner, V. and Reidy, M. A. (1996) Arterio. Thromb. Vasc. Biol. 16, 1399–1405.

    CAS  Google Scholar 

  222. Bauerschmitz, G. J., Nettelbeck, D. M., Kanerva, A., Baker, A. H., Hemminki, A., Reynolds, P. N. and Curiel, D. T. (2002)Cancer Res. 62, 1271–1274.

    PubMed  CAS  Google Scholar 

  223. Mimuro, J., Muramatsu, S., Hakamada, Y., Mori, K., Kikuchi, J., Urabe, M., Madoiwa, S., Ozawa, K. and Sakata, Y. (2001)Gene Ther. 8, 1690–1697.

    PubMed  CAS  Google Scholar 

  224. Prentice, H., Bishopric, N. H., Hicks, M. N., Discher, D. J., Wu, X., Wylie, A. A. and Webster, K. A. (1997)Cardio. Res. 35, 567–574.

    CAS  Google Scholar 

  225. Aikawa, R., Huggins, G. S. and Snyder, R. O. (2002)J. Biol. Chem. 277, 18979–18985.

    PubMed  CAS  Google Scholar 

  226. Su, H., Arakawa-Hoyt, J. and Kan, Y. W. (2002) Proc. Nat. Acad. Sci. U.S.A. 99 (14), 9480–9485.

    CAS  Google Scholar 

  227. Griscelli, F., Gilardi-Hebenstreit, P., Hanania, N., Franz, W.-M., Opolon, P., Perricaudet, M. and Ragout, T. (1998) Hum. Gene Ther. 9, 1919–1928.

    PubMed  CAS  Google Scholar 

  228. Phillips, M. I., Tang, Y., Schmidt-Ott, K., Qian, K. and Kagiyama, S. (2002)Hypertension 39, 651–655.

    PubMed  CAS  Google Scholar 

  229. Moessler, H., Mericskay, M., Li, Z., Nagl, S., Paulin, D. and Small, J. V. (1996)Development 122, 2415–2425.

    PubMed  CAS  Google Scholar 

  230. Ribault, S., Neuville, P., Mechine-Neuville, A., Auge, F., Parlakian, A., Gabbiani, G,Paulin, D. and Calenda, V. (2001)Circ. Res. 88, 468–475.

    PubMed  CAS  Google Scholar 

  231. Keogh, M.-C., Chen, D., Schmitt, J. F., Kakkar, V. V. and Lemoine, N. R. (1999)Gene Ther. 6, 616–628.

    PubMed  CAS  Google Scholar 

  232. Wills, K. N., Mano, T., Avanzini, J. B., Nguyen, T., Antelman, D., Gregory, R. J., Smith, R. C. and Walsh, K. (2001)Gene Ther. 8, 1847–1854.

    PubMed  CAS  Google Scholar 

  233. Li, X., Eastman, E. M., Schwartz, R. J. and Draghia-Akli, R. (1999)Nature Biotechnol.17, 241–245.

    CAS  Google Scholar 

  234. Edelman, G. M., Meech, R., and Jones, F. S. (2000)Proc. Nat. Acad. Sci.U.S.A. 97, 3038–3043.

    CAS  Google Scholar 

  235. Gossen, M. and Bujard, H. (1992) Proc. Nat. Acad. Sci. U.S.A. 89, 5547–5551.

    CAS  Google Scholar 

  236. Gossen, M., Freundlieb, S., Bender, G., Muller, G., Hillen, W. and Bujard, H. (1995)Science 268, 1766–1769.

    PubMed  CAS  Google Scholar 

  237. Ghersa, P., Pescini Gobert, R., Sattonnet-Roche, P., Richards, C. A., Merlo Pic.And Hooft van Huijduijnen, R. (1998)Gene Ther. 5, 1213–1220.

    PubMed  CAS  Google Scholar 

  238. Rubinchik, S., Wang, D., Yu, H., Fan, F., Luo, M., Norris, J. S. and Dong, J.-Y. (2001)Mol. Ther. 4, 416–426.

    PubMed  CAS  Google Scholar 

  239. Smith-Arica, J. R., Morelli, A. E., Larregina, A. T., Smith, J., Lowenstein, P. R. And Castro, M. G. (2000)Mol. Ther. 2, 579–587.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2003 Springer Science+Business Media New York

About this chapter

Cite this chapter

Nicklin, S.A., Baker, A.H. (2003). Development of Targeted Viral Vectors for Cardiovascular Gene Therapy. In: Setlow, J.K. (eds) Genetic Engineering. Genetic Engineering: Principles and Methods, vol 25. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0073-5_2

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-0073-5_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4911-2

  • Online ISBN: 978-1-4615-0073-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics