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Diagnosis and Clinical Evaluation of Nasopharyngeal Carcinoma

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Nasopharyngeal Carcinoma

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 778))

Abstract

Nasopharyngeal carcinoma (NPC) is an epithelial malignant tumor which arises from the mucosa of the nasopharyngeal cavity. NPC usually presents as painless neck lumps. It can also present with nasal, aural and/or opthalmo-neurologic symptoms. Patients in early stage of the disease are often asymptomatic or present with apparently trivial symptoms. Diagnosis is based on histopathological examination of the biopsied tissue obtained through endoscopy of the nasopharynx. Delayed diagnosis remains a problem in NPC. The most common used staging system is the “tumor node metastasis (TNM)” system, jointly developed by the American Joint Committee on Cancer (AJCC) and the Union for International Cancer Control (UICC).

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Author information

Authors and Affiliations

  1. Molecular Pathology Unit, Cancer Research Centre, Institute for Medical Research, Kuala Lumpur, Malaysia

    Alan Soo-Beng Khoo

  2. Department of Otorhinolaryngology, Penang General Hospital, Penang, Malaysia

    Kin-Choo Pua

Authors
  1. Alan Soo-Beng Khoo
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  2. Kin-Choo Pua
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Corresponding author

Correspondence to Alan Soo-Beng Khoo .

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Editors and Affiliations

  1. CNRS and Institut de Cancérologie Gustave Roussy, Université Paris-Sud 11, UMR 8126, Villejuif, France

    Pierre Busson MD, PhD

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© 2013 Landes Bioscience and Springer Science+Business Media, LLC

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Khoo, A.SB., Pua, KC. (2013). Diagnosis and Clinical Evaluation of Nasopharyngeal Carcinoma. In: Busson, P. (eds) Nasopharyngeal Carcinoma. Advances in Experimental Medicine and Biology, vol 778. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-5947-7_1

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