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GER and Aspiration in Interstitial Lung Disease

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Gastroesophageal Reflux and the Lung

Part of the book series: Respiratory Medicine ((RM,volume 2))

Abstract

Many investigations have linked gastroesophageal reflux (GER) to various forms of interstitial lung disease (ILD) including idiopathic pulmonary fibrosis (IPF), scleroderma, and other connective tissue diseases (CTD). However, definitive proof that abnormal GER and microaspiration is a cause of ILD, promotes disease progression, or precipitates acute exacerbation of IPF or other forms of ILD is lacking. Nonetheless, evidence is accumulating that suggests that abnormal GER and microaspiration of refluxed gastroduodenal secretions may play a significant role in IPF, scleroderma, and other ILD. This chapter examines the published evidence and provides an assessment of the current state of knowledge of the role of GER and microaspiration in ILD.

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Authors and Affiliations

  1. Department of Medicine, University of Wisconsin School of Medicine and Public Health, K4/910 CSC, 600 Highland Avenue, Madison, WI, 53792-9988, USA

    Keith C. Meyer M.D., M.S.

  2. Division of Pulmonary & Critical Care Medicine, University of Washington Medical Center, 356175, Seattle, WA, 98195-6522, USA

    Ganesh Raghu M.D., F.C.C.P., F.A.C.P.

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  1. Keith C. Meyer M.D., M.S.
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  2. Ganesh Raghu M.D., F.C.C.P., F.A.C.P.
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Correspondence to Keith C. Meyer M.D., M.S. .

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Editors and Affiliations

  1. , Department of Medicine, University of Wisconsin School of Medici, 600 Highland Avenue, Madison, 53792-9988, Wisconsin, USA

    Keith C. Meyer

  2. , Division of Pulmonary and Critical Care, University of Washington School of Medic, Campus Box 356175, Seatt;e, 98195, Washington, USA

    Ganesh Raghu

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Meyer, K.C., Raghu, G. (2012). GER and Aspiration in Interstitial Lung Disease. In: Meyer, K., Raghu, G. (eds) Gastroesophageal Reflux and the Lung. Respiratory Medicine, vol 2. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4614-5502-8_10

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  • DOI: https://doi.org/10.1007/978-1-4614-5502-8_10

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